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Biology and Biochemistry

D-Index
54
Citations
11553
World Ranking
15546
National Ranking
1092

Overview

Valeri Zakhartchenko is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research spans multiple scientific disciplines, primarily focusing on biochemistry, genetics, and molecular biology as well as medicine.

The main fields of study associated with Valeri Zakhartchenko include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work further extends into several subfields such as:

  • Molecular Biology
  • Surgery
  • Genetics
  • Physiology
  • Biomedical Engineering

Valeri Zakhartchenko's research topics cover a variety of areas, including:

  • CRISPR and Genetic Engineering
  • Muscle Physiology and Disorders
  • Xenotransplantation and immune response
  • Pluripotent Stem Cells Research
  • Virus-based gene therapy research
  • Animal Genetics and Reproduction
  • Pancreatic function and diabetes

Frequent publication venues where Valeri Zakhartchenko's work has appeared include:

  • International Journal of Molecular Sciences
  • Xenotransplantation
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Medicine

Valeri is also known for collaboration with several coauthors, notably:

  • Eckhard Wolf
  • Mayuko Kurome
  • Barbara Keßler
  • Elisabeth Kemter
  • Nikolai Klymiuk

Their recent papers reflect a focus on genetic engineering, transplantation biology, and disease modeling:

  • Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy, 2020, Nature Medicine
  • Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation?, 2020, The Journal of Heart and Lung Transplantation
  • Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies, 2020, Xenotransplantation
  • Cas9-expressing chickens and pigs as resources for genome editing in livestock, 2021, Proceedings of the National Academy of Sciences
  • A scalable, clinically severe pig model for Duchenne muscular dystrophy, 2021, Disease Models & Mechanisms

Best Publications

  • Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos.

    Wendy Dean;Fátima Santos;Miodrag Stojkovic;Valeri Zakhartchenko

  • 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

    Mark Wossidlo;Toshinobu Nakamura;Konstantin Lepikhov;C. Joana Marques

  • Mitochondrial distribution and adenosine triphosphate content of bovine oocytes before and after in vitro maturation: correlation with morphological criteria and developmental capacity after in vitro fertilization and culture.

    Miodrag Stojkovic;Sergio A. Machado;Petra Stojkovic;Valeri Zakhartchenko

  • Epigenetic Marking Correlates with Developmental Potential in Cloned Bovine Preimplantation Embryos

    Fátima Santos;Valeri Zakhartchenko;Miodrag Stojkovic;Antoine Peters

  • Consistent success in life-supporting porcine cardiac xenotransplantation

    Matthias Längin;Tanja Mayr;Bruno Reichart;Sebastian Michel

  • Fine mapping of genome activation in bovine embryos by RNA sequencing.

    Alexander Graf;Stefan Krebs;Valeri Zakhartchenko;Björn Schwalb

  • The endometrium responds differently to cloned versus fertilized embryos

    Stefan Bauersachs;Susanne E. Ulbrich;Valeri Zakhartchenko;Megan Minten

  • Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

    Ralf Steinborn;Pamela Schinogl;Valeri Zakhartchenko;Roland Achmann

  • Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts.

    V. Zakhartchenko;G. Durcova-Hills;M. Stojkovic;W. Schernthaner

  • Adult cloning in cattle: potential of nuclei from a permanent cell line and from primary cultures.

    Valeri Zakhartchenko;Ramiro Alberio;Miodrag Stojkovic;Katja Prelle

  • Generation of Transgenic Cattle by Lentiviral Gene Transfer into Oocytes

    Andreas Hofmann;Valeri Zakhartchenko;Myriam Weppert;Heidi Sebald

  • Methylation Reprogramming and Chromosomal Aneuploidy in In Vivo Fertilized and Cloned Rabbit Preimplantation Embryos

    Wei Shi;Fatma Dirim;Eckhard Wolf;Valeri Zakhartchenko

  • Epigenetic reprogramming in mammalian nuclear transfer

    Wei Shi;Valeri Zakhartchenko;Eckhard Wolf

  • Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

    A. Moretti;L. Fonteyne;F. Giesert;P. Hoppmann

  • Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

    Nikolai Klymiuk;Andreas Blutke;Alexander Graf;Sabine Krause

  • Genome activation in bovine embryos: Review of the literature and new insights from RNA sequencing experiments

    Alexander Graf;Stefan Krebs;Mari Heininen-Brown;Valeri Zakhartchenko

  • Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing

    Konrad Fischer;Simone Kraner-Scheiber;Björn Petersen;Beate Rieblinger

  • Mammalian oocyte activation: lessons from the sperm and implications for nuclear transfer.

    Ramiro Alberio;Valeri Zakhartchenko;Jan Motlik;Eckhard Wolf

  • Tissue-Specific Elevated Genomic Cytosine Methylation Levels Are Associated with an Overgrowth Phenotype of Bovine Fetuses Derived by In Vitro Techniques

    Stefan Hiendleder;Cora Mund;Horst Dieter Reichenbach;Hendrik Wenigerkind

  • Effects of high concentrations of hyaluronan in culture medium on development and survival rates of fresh and frozen-thawed bovine embryos produced in vitro

    M Stojkovic;S Kolle;S Peinl;P Stojkovic

Frequent Co-Authors

Eckhard Wolf
Eckhard Wolf Ludwig-Maximilians-Universität München
Gottfried Brem
Gottfried Brem University of Veterinary Medicine Vienna
Miodrag Stojkovic
Miodrag Stojkovic University of Kragujevac
Thomas Cremer
Thomas Cremer Ludwig-Maximilians-Universität München
Helmut Blum
Helmut Blum Ludwig-Maximilians-Universität München
Mathias Müller
Mathias Müller University of Veterinary Medicine Vienna
Fred Sinowatz
Fred Sinowatz Ludwig-Maximilians-Universität München
Bruno Reichart
Bruno Reichart Ludwig-Maximilians-Universität München

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