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Biology and Biochemistry

D-Index
66
Citations
18801
World Ranking
8543
National Ranking
627

Overview

Helmut Blum is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on several subfields including Molecular Biology, Infectious Diseases, Immunology, Genetics, and Epidemiology.

The scientist's main research topics cover areas with considerable relevance to public health and molecular science. These topics include SARS-CoV-2 and COVID-19 Research, SARS-CoV-2 detection and testing, COVID-19 Clinical Research Studies, Biosensors and Analytical Detection, CRISPR and Genetic Engineering, Acute Myeloid Leukemia Research, and RNA Research and Splicing.

Helmut Blum has published a number of papers with significant contributions to the understanding of infectious diseases and molecular biology. Some recent notable publications are:

  • "Swarm Learning for decentralized and confidential clinical machine learning" (2021, Nature)
  • "Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern" (2022, Nature Medicine)
  • "Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19" (2021, Immunity)
  • "Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy" (2020, Nature Medicine)
  • "Impaired detection of omicron by SARS-CoV-2 rapid antigen tests" (2022, Medical Microbiology and Immunology)

The scientist has frequently collaborated with other researchers in their field. The most frequent coauthors include:

  • Stefan Krebs
  • Alexander Graf
  • Oliver T. Keppler
  • Maximilian Muenchhoff
  • Julia Philippou-Massier

Publication activity shows a tendency to appear regularly in several academic journals and platforms. These venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Medical Microbiology and Immunology
  • Scientific Reports
  • Nature Communications
  • Infection

Helmut Blum's work intersects with ongoing global challenges, especially in the context of infectious diseases and molecular biology, providing data and findings related to SARS-CoV-2, genetic engineering techniques, and clinical applications. The combination of fields and topics reflects multidisciplinary research integral to public health and molecular research.

Best Publications

  • LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

    Irina Solovei;Audrey S. Wang;Katharina Thanisch;Christine S. Schmidt

  • Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells

    Sylvia Heink;Nir Yogev;Christoph Garbers;Marina Herwerth

  • Fine mapping of genome activation in bovine embryos by RNA sequencing.

    Alexander Graf;Stefan Krebs;Valeri Zakhartchenko;Björn Schwalb

  • Whole exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

    Martin Neumann;Sandra Heesch;Cornelia Schlee;Stefan Schwartz

  • The endometrium responds differently to cloned versus fertilized embryos

    Stefan Bauersachs;Susanne E. Ulbrich;Valeri Zakhartchenko;Megan Minten

  • Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity

    Stefan Bauersachs;Susanne E Ulbrich;Karin Gross;Susanne E M Schmidt

  • Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling

    Andreas Herbst;Vindi Jurinovic;Stefan Krebs;Susanne E Thieme

  • Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

    Benjamin Krämer;Rainer Knoll;Lorenzo Bonaguro;Michael ToVinh

  • Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

    Stefan Wiemann;Bernd Weil;Ruth Wellenreuther;Johannes Gassenhuber

  • Embryo-Maternal Communication in Bovine – Strategies for Deciphering a Complex Cross-Talk

    Wolf E;Arnold Gj;Bauersachs S;Beier Hm

  • Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020.

    Erik Alm;Eeva K Broberg;Thomas Connor;Emma B Hodcroft

  • Comparative Kinetics of Escherichia coli- and Staphylococcus aureus-Specific Activation of Key Immune Pathways in Mammary Epithelial Cells Demonstrates That S. aureus Elicits a Delayed Response Dominated by Interleukin-6 (IL-6) but Not by IL-1A or Tumor Necrosis Factor Alpha

    Juliane Günther;Kathrin Esch;Norbert Poschadel;Wolfram Petzl

  • Monozygotic Twin Model Reveals Novel Embryo-Induced Transcriptome Changes of Bovine Endometrium in the Preattachment Period

    Claudia Klein;Stefan Bauersachs;Susanne E. Ulbrich;Ralf Einspanier

  • Roquin Paralogs 1 and 2 Redundantly Repress the Icos and Ox40 Costimulator mRNAs and Control Follicular Helper T Cell Differentiation

    Katharina U. Vogel;Stephanie L. Edelmann;Katharina M. Jeltsch;Arianna Bertossi

  • Gene expression profiling of bovine endometrium during the oestrous cycle: detection of molecular pathways involved in functional changes

    Stefan Bauersachs;Susanne E Ulbrich;Karin Gross;Susanne E M Schmidt

  • Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

    A. Moretti;L. Fonteyne;F. Giesert;P. Hoppmann

  • Monitoring gene expression changes in bovine oviduct epithelial cells during the oestrous cycle

    S Bauersachs;S Rehfeld;SE Ulbrich;S Mallok

  • GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia

    Philipp A. Greif;Annika Dufour;Nikola P. Konstandin;Bianka Ksienzyk

  • Bovine Polledness - An Autosomal Dominant Trait with Allelic Heterogeneity

    Ivica Medugorac;Doris Seichter;Alexander Graf;Ingolf Russ

  • Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

    Nikolai Klymiuk;Andreas Blutke;Alexander Graf;Sabine Krause

Frequent Co-Authors

Eckhard Wolf
Eckhard Wolf Ludwig-Maximilians-Universität München
Stefan Bauersachs
Stefan Bauersachs University of Zurich
Stefan K. Bohlander
Stefan K. Bohlander University of Auckland
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Valeri Zakhartchenko
Valeri Zakhartchenko Ludwig-Maximilians-Universität München
Wolfgang E. Berdel
Wolfgang E. Berdel University of Münster
Andreas Jung
Andreas Jung University of Zurich
Fred Sinowatz
Fred Sinowatz Ludwig-Maximilians-Universität München
Jochen Hecht
Jochen Hecht Centre for Genomic Regulation

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