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Genetics

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45
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10105
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4213
National Ranking
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Overview

Jochen Hecht is affiliated with the Centre for Genomic Regulation in Spain and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including infectious diseases, molecular biology, periodontics, ecology, and genetics.

Hecht's research interests focus on topics such as SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, SARS-CoV-2 detection and testing, gut microbiota and health, genomics and phylogenetic studies, oral microbiology and periodontitis research, as well as epigenetics and DNA methylation.

The scientist has published work in a variety of venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Oral Microbiology
  • Cell
  • Nature Medicine

Key recent papers by Jochen Hecht include:

  • Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital (2020, Nature Communications)
  • A global metagenomic map of urban microbiomes and antimicrobial resistance (2021, Cell)
  • Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment (2020, Nature Medicine)
  • Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • SARS-CoV-2 Seroprevalence and Antibody Kinetics Among Health Care Workers in a Spanish Hospital After 3 Months of Follow-up (2020, The Journal of Infectious Diseases)

Jochen Hecht has collaborated with several frequent coauthors, including:

  • Carlo Carolis
  • Alberto L. García-Basteiro
  • Gemma Moncunill
  • Marta Tortajada
  • Marta Vidal

Their research contributions show an interdisciplinary approach, combining clinical and molecular approaches to infectious disease study and genomic surveillance. This is reflected in their publication record emphasizing viruses, antibody response, microbial environments, and antimicrobial resistance.

Best Publications

  • Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

    Darío G. Lupiáñez;Darío G. Lupiáñez;Katerina Kraft;Katerina Kraft;Verena Heinrich;Peter Krawitz;Peter Krawitz

  • Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

    Alexander Hruscha;Peter Krawitz;Peter Krawitz;Alexandra Rechenberg;Verena Heinrich

  • European sea bass genome and its variation provide insights into adaptation to euryhalinity and speciation

    Mbaye Tine;Heiner Kuhl;Pierre-Alexandre Gagnaire;Bruno Louro

  • Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome

    Peter M Krawitz;Peter M Krawitz;Michal R Schweiger;Michal R Schweiger;Christian Rödelsperger;Christian Rödelsperger;Carlo Marcelis

  • A global metagenomic map of urban microbiomes and antimicrobial resistance

    David Danko;Daniela Bezdan;Evan E. Afshin;Sofia Ahsanuddin

  • Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming

    Ralph Stadhouders;Ralph Stadhouders;Enrique Vidal;François Serra;Bruno Di Stefano;Bruno Di Stefano

  • Mutations in WNT1 Cause Different Forms of Bone Fragility

    Katharina Keupp;Filippo Beleggia;Hülya Kayserili;Aileen M. Barnes

  • Whole exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

    Martin Neumann;Sandra Heesch;Cornelia Schlee;Stefan Schwartz

  • Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

    Daniel Kotlarz;Natalia Ziętara;Gulbu Uzel;Thomas Weidemann

  • Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome

    Tomasz Zemojtel;Sebastian Köhler;Luisa Mackenroth;Marten Jäger

  • PDE3A mutations cause autosomal dominant hypertension with brachydactyly

    Philipp G Maass;Atakan Aydin;Friedrich C Luft;Carolin Schächterle

  • TCR repertoire analysis by next generation sequencing allows complex differential diagnosis of T cell-related pathology.

    M Dziubianau;J Hecht;Leon Kuchenbecker;A Sattler

  • Mutations in PIGO, a member of the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation.

    Peter M. Krawitz;Peter M. Krawitz;Yoshiko Murakami;Jochen Hecht;Jochen Hecht;Ulrike Krüger

  • High-throughput polymorphism detection and genotyping in Brassica napus using next-generation RAD sequencing

    Anja Bus;Jochen Hecht;Bruno Huettel;Richard Reinhardt

  • Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus

    Malte Spielmann;Francesco Brancati;Francesco Brancati;Peter M. Krawitz;Peter N. Robinson

  • Deep Sequencing of MYC DNA-Binding Sites in Burkitt Lymphoma

    Volkhard Seitz;Peter Butzhammer;Burkhard Hirsch;Jochen Hecht

  • PGAP2 Mutations, Affecting the GPI-Anchor-Synthesis Pathway, Cause Hyperphosphatasia with Mental Retardation Syndrome

    Peter M. Krawitz;Yoshiko Murakami;Angelika Rieß;Marja Hietala

  • Mutational spectrum of adult T-ALL

    Martin Neumann;Sebastian Vosberg;Cornelia Schlee;Sandra Heesch

  • Delineation of a contiguous gene syndrome with multiple exostoses, enlarged parietal foramina, craniofacial dysostosis, and mental retardation, caused by deletions on the short arm of chromosome 11

    O. Bartsch;Wim Wuyts;W. Van Hul;J. T. Hecht

  • Copy-Number Variations Involving the IHH Locus Are Associated with Syndactyly and Craniosynostosis

    Eva Klopocki;Silke Lohan;Silke Lohan;Silke Lohan;Francesco Brancati;Francesco Brancati;Randi Koll

Frequent Co-Authors

Stefan Mundlos
Stefan Mundlos Max Planck Society
Peter N. Robinson
Peter N. Robinson The Jackson Laboratory
Sigmar Stricker
Sigmar Stricker Freie Universität Berlin
Uwe Kornak
Uwe Kornak University of Göttingen
Helmut Blum
Helmut Blum Ludwig-Maximilians-Universität München
Eva Klopocki
Eva Klopocki University of Würzburg
Bernd Timmermann
Bernd Timmermann Max Planck Society
Francesco Brancati
Francesco Brancati University of L'Aquila
Taroh Kinoshita
Taroh Kinoshita Osaka University
Petra Reinke
Petra Reinke Berlin-Brandenburger Centrum für Regenerative Therapien

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