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Molecular Biology

D-Index
48
Citations
6542
World Ranking
2699
National Ranking
183

Overview

Sigmar Stricker is affiliated with Freie Universität Berlin in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant focus on Molecular Biology, Genetics, Oncology, Pulmonary and Respiratory Medicine, and Surgery.

The scientist's work covers key topics including Muscle Physiology and Disorders, Congenital Heart Defects Research, Adipose Tissue and Metabolism, Developmental Biology and Gene Regulation, Lymphatic System and Diseases, Neurogenetic and Muscular Disorders Research, and Neurofibromatosis and Schwannoma Cases.

Recent publications illustrate their contributions to the understanding of muscle biology and immune responses. Notable papers include:

  • Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair, 2021, Science Advances
  • Pre-activated anti-viral innate immunity in the upper airways controls early SARS-CoV-2 infection in children, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Tissue cross talks governing limb muscle development and regeneration, 2020, Seminars in Cell and Developmental Biology
  • Local retinoic acid signaling directs emergence of the extraocular muscle functional unit, 2020, PLoS Biology
  • Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors, 2023, npj Regenerative Medicine

Their frequent co-authors include Pedro Vallecillo-García, Sophie Pöhle-Kronawitter, Bernd Timmermann, Georgios Kotsaris, and Claudia Giesecke-Thiel. Collaboration is a significant aspect of their research, contributing to a range of multidisciplinary studies.

Publishing frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, SSRN Electronic Journal, Development, and Genetics in Medicine, the scientist demonstrates a broad engagement with both preprint platforms and peer-reviewed journals.

Best Publications

  • BMP signaling controls muscle mass

    Roberta Sartori;Elija Schirwis;Bert Blaauw;Sergia Bortolanza

  • Role of Runx Genes in Chondrocyte Differentiation

    Sigmar Stricker;Reinald Fundele;Andrea Vortkamp;Stefan Mundlos

  • Mutations in WNT7A Cause a Range of Limb Malformations, Including Fuhrmann Syndrome and Al-Awadi/Raas-Rothschild/Schinzel Phocomelia Syndrome

    C. G. Woods;S. Stricker;P. Seemann;R. Stern

  • Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

    Petra Seemann;Raphaela Schwappacher;Klaus W. Kjaer;Deborah Krakow

  • Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

    Florian Witte;Janine Dokas;Franziska Neuendorf;Stefan Mundlos

  • Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2.

    Katarina Lehmann;Petra Seemann;Sigmar Stricker;Marai Sammar

  • A molecular pathogenesis for transcription factor associated poly-alanine tract expansions.

    Andrea N. Albrecht;Uwe Kornak;Annett Böddrich;Kathrin Süring

  • PDE3A mutations cause autosomal dominant hypertension with brachydactyly

    Philipp G Maass;Atakan Aydin;Friedrich C Luft;Carolin Schächterle

  • Escobar Syndrome Is a Prenatal Myasthenia Caused by Disruption of the Acetylcholine Receptor Fetal γ Subunit

    Katrin Hoffmann;Juliane S. Müller;Sigmar Stricker;Andre Megarbane

  • Multiple roles for neurofibromin in skeletal development and growth

    Mateusz Kolanczyk;Nadine Kossler;Jirko Kühnisch;Liron Lavitas

  • Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders

    Anne Michalk;Sigmar Stricker;Jutta Becker;Rosemarie Rupps

  • Duplications of noncoding elements 5' of SOX9 are associated with brachydactyly-anonychia.

    Ingo Kurth;Eva Klopocki;Sigmar Stricker;Jolieke van Oosterwijk

  • Faulty Initiation of Proteoglycan Synthesis Causes Cardiac and Joint Defects

    Sevjidmaa Baasanjav;Lihadh Al-Gazali;Taishi Hashiguchi;Shuji Mizumoto

  • Mutations in PVRL4, Encoding Cell Adhesion Molecule Nectin-4, Cause Ectodermal Dysplasia-Syndactyly Syndrome

    Francesco Brancati;Francesco Brancati;Paola Fortugno;Irene Bottillo;Marc Lopez

  • A misplaced lncRNA causes brachydactyly in humans

    Philipp G. Maass;Andreas Rump;Herbert Schulz;Sigmar Stricker

  • Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2

    Marei Sammar;Sigmar Stricker;Georg C. Schwabe;Christina Sieber

  • Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN

    Petra Seemann;Petra Seemann;Anja Brehm;Jana König;Jana König;Jana König;Carsten Reissner

  • Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development

    Pedro Vallecillo-García;Pedro Vallecillo-García;Mickael Orgeur;Sophie vom Hofe-Schneider;Jürgen Stumm;Jürgen Stumm

  • Copy-Number Variations Involving the IHH Locus Are Associated with Syndactyly and Craniosynostosis

    Eva Klopocki;Silke Lohan;Silke Lohan;Silke Lohan;Francesco Brancati;Francesco Brancati;Randi Koll

  • A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range

    Bo Gao;Jianxin Hu;Jianxin Hu;Sigmar Stricker;Martin Cheung

Frequent Co-Authors

Stefan Mundlos
Stefan Mundlos Max Planck Society
Delphine Duprez
Delphine Duprez Université Paris Cité
Jochen Hecht
Jochen Hecht Centre for Genomic Regulation
Eva Klopocki
Eva Klopocki University of Würzburg
Bernd Timmermann
Bernd Timmermann Max Planck Society
Petra Knaus
Petra Knaus Freie Universität Berlin
Francesco Brancati
Francesco Brancati University of L'Aquila
Peter N. Robinson
Peter N. Robinson The Jackson Laboratory
Walter Sebald
Walter Sebald University of Würzburg
Aris N. Economides
Aris N. Economides Regeneron (United States)

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