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Immunology

D-Index
68
Citations
14120
World Ranking
2623
National Ranking
27

Overview

Carlos López-Larrea is affiliated with the Central University Hospital of Asturias in Spain. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a notable focus on Infectious Diseases, Immunology, and Molecular Biology as significant subfields.

The scientist has contributed extensively to research topics related to COVID-19 Clinical Research Studies and SARS-CoV-2 and COVID-19 Research. Other main topics in their work include the Complement system in diseases, Protein Degradation and Inhibitors, Autophagy in Disease and Therapy, Endoplasmic Reticulum Stress and Disease, and Multiple Myeloma Research and Treatments.

Frequent publication venues for their work include:

  • Nephrology Dialysis Transplantation
  • Preprints.org
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences

Carlos López-Larrea has collaborated frequently with several coauthors, including:

  • Beatriz Suárez-Álvarez
  • María Laura Sáiz
  • Marta Ruiz-Ortega
  • Viviana Corte-Iglesias
  • Raúl R. Rodrigues-Díez

Among recent publications, notable papers include:

  • "Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome," 2020, Gene
  • "Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization," 2020, Frontiers in Immunology
  • "The Interferon-induced transmembrane protein 3 gene (IFITM3) rs12252 C variant is associated with COVID-19," 2020, Cytokine
  • "Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity," 2021, Clinical Epigenetics
  • "Variant-genetic and transcript-expression analysis showed a role for the chemokine-receptor CCR5 in COVID-19 severity," 2021, International Immunopharmacology

Best Publications

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D M Evans;Spencer Cca.;J J Pointon;Z Su

  • Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.

    A Cortes;J Hadler;J P Pointon

  • The Inflammatory Cytokines TWEAK and TNFα Reduce Renal Klotho Expression through NFκB

    Juan A. Moreno;Maria C. Izquierdo;Maria D. Sanchez-Niño;Beatriz Suárez-Alvarez

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D.M. Evans;C.C.A. Spencer;J.J. Pointon;Z. Su

  • Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.

    Adrian Cortes;Sara L. Pulit;Paul J. Leo;Jenny J. Pointon

  • NKG2D ligands: key targets of the immune response

    Segundo González;Alejandro López-Soto;Beatriz Suarez-Alvarez;Antonio López-Vázquez

  • HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis

    S. Gonzalez-Roces;M. V. Alvarez;S. Gonzalez;A. Dieye

  • When Aging Reaches CD4+ T-Cells: Phenotypic and Functional Changes

    Marco Antonio Moro-García;Rebeca Alonso-Arias;Carlos Lopez-Larrea

  • Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome.

    Juan Gómez;Guillermo M. Albaiceta;Marta García-Clemente;Carlos López-Larrea

  • The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis.

    Segundo Gonzalez;J. Martinez‐Borra;J. C. Torre‐Alonso;S. Gonzalez‐Roces

  • Sirtuin 1 regulation of developmental genes during differentiation of stem cells

    Vincenzo Calvanese;Ester Lara;Beatriz Suárez-Álvarez;Raed Abu Dawud

  • Protective Effect of the HLA-Bw4I80 Epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 Gene against the Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection

    Antonio López-Vázquez;Luis Rodrigo;Jesús Martínez-Borra;Ramón Pérez

  • TNF-α −308A promoter polymorphism is associated with enhanced TNF-α production and inflammatory activity in Crohn’s patients with fistulizing disease

    Segundo González;Luis Rodrigo;Jesús Martínez-Borra;Antonio López-Vázquez

  • DNA methylation: a promising landscape for immune system-related diseases.

    Beatriz Suarez-Alvarez;Ramon M. Rodriguez;Mario F. Fraga;Carlos López-Larrea

  • The NKG2D receptor: sensing stressed cells.

    Carlos López-Larrea;Beatriz Suárez-Alvarez;Alejandro López-Soto;Antonio López-Vázquez

  • Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization.

    Paula Díaz-Bulnes;María Laura Saiz;Carlos López-Larrea;Ramón M. Rodríguez

  • High serum tumor necrosis factor-α levels are associated with lack of response to infliximab in fistulizing Crohn’s disease

    Jesús Martínez-Borra;Carlos López-Larrea;Segundo González;Dolores Fuentes

  • Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects

    Marco Antonio Moro-García;Rebeca Alonso-Arias;Maria Baltadjieva;Carlos Fernández Benítez

  • The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection.

    B. Suárez-Álvarez;A. López-Vázquez;M. Zapico Gonzalez;J. L. Fdez-Morera

  • MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201

    A Lopez-Vazquez;L Rodrigo;D Fuentes;S Riestra

  • Mobilization and homing of hematopoietic stem cells.

    Beatriz Suárez-Álvarez;Antonio López-Vázquez;Carlos López-Larrea

  • Polymorphism in MICA rather than HLA-B/C genes is associated with psoriatic arthritis in the Jewish population.

    Segundo González;Chaim Brautbar;J Martı́nez-Borra;A López-Vazquez

  • Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

    A. Cortes;J. Hadler;J.P. Pointon;P.C. Robinson

Frequent Co-Authors

Segundo González
Segundo González University of Oviedo
Eliecer Coto
Eliecer Coto University of Oviedo
Victoria Alvarez
Victoria Alvarez University of Oviedo
Marta Ruiz-Ortega
Marta Ruiz-Ortega Autonomous University of Madrid
Mario F. Fraga
Mario F. Fraga University of Oviedo
Francisco Ortega
Francisco Ortega Institució Catalana de Recerca i Estudis Avançats
Alberto Ortiz
Alberto Ortiz Autonomous University of Madrid
Agustín F. Fernández
Agustín F. Fernández University of Oviedo
Jesús Egido
Jesús Egido Autonomous University of Madrid
David Evans
David Evans University of Bristol

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Related Online Degrees & Career Pathways

For those interested in Immunology, pursuing related healthcare degrees can broaden career opportunities in research, patient care, and specialized clinical roles. Many professionals start with foundational nursing programs before advancing into more focused fields, such as immunology research or clinical immunology practice.

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Advanced practice nurses can specialize further by enrolling in accelerated NP programs online, allowing for accelerated transition into nurse practitioner roles. Specifically, those aiming to work in acute settings related to immunology research or care might pursue an FNP to acute care certification, which facilitates specialization in managing complex patients with immune system disorders.

Overall, exploring these pathways alongside Immunology studies can open doors to rewarding careers bridging scientific research and patient-centered healthcare.

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