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Segundo González

Segundo González

D-Index & Metrics

Immunology

D-Index
51
Citations
7890
World Ranking
4174
National Ranking
47

Overview

Segundo González is affiliated with the University of Oviedo in Spain. Their research primarily focuses on fields related to Medicine and Immunology and Microbiology, contributing notably to both areas with 33 and 21 publications respectively. Within these domains, their subfields of study include Immunology, Oncology, Molecular Biology, Pathology and Forensic Medicine, and Genetics.

The research topics Segundo González addresses encompass several important areas of biomedical science. These include:

  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Chronic Lymphocytic Leukemia Research
  • CAR-T cell therapy research
  • Lymphoma Diagnosis and Treatment
  • Lung Cancer Research Studies
  • T-cell and B-cell Immunology

Segundo González has contributed to multiple papers in prominent journals. Notable recent publications include:

  • "Chemo-Immunotherapy: A New Trend in Cancer Treatment" (2023) in Cancers
  • "Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer" (2020) in International Journal of Molecular Sciences
  • "LAG-3 Blockade with Relatlimab (BMS-986016) Restores Anti-Leukemic Responses in Chronic Lymphocytic Leukemia" (2021) in Cancers
  • "Beyond the anti-PD-1/PD-L1 era: promising role of the BTLA/HVEM axis as a future target for cancer immunotherapy" (2023) in Molecular Cancer
  • "Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance" (2020) in Molecular Cancer Therapeutics

The scientist frequently publishes in journals such as Cancers, Biomarker Research, Methods in Molecular Biology, International Journal of Molecular Sciences, and Molecular Cancer.

Frequent collaborators of Segundo González include Christian Sordo-Bahamonde, Seila Lorenzo-Herrero, Alejandra Martínez-Pérez, Ana Pilar González, and Candelaria Aguilar-García. These partnerships highlight ongoing efforts within collaborative research networks focusing on related biomedical topics.

Best Publications

  • Control of Metastasis by NK Cells

    Alejandro López-Soto;Segundo Gonzalez;Mark J. Smyth;Lorenzo Galluzzi;Lorenzo Galluzzi

  • Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands

    Brett K Kaiser;Daesong Yim;I-Ting Chow;Segundo Gonzalez;Segundo Gonzalez

  • NKG2D ligands: key targets of the immune response

    Segundo González;Alejandro López-Soto;Beatriz Suarez-Alvarez;Antonio López-Vázquez

  • Immunobiology of human NKG2D and its ligands.

    S González;V Groh;T Spies

  • HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis

    S. Gonzalez-Roces;M. V. Alvarez;S. Gonzalez;A. Dieye

  • The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis.

    Segundo Gonzalez;J. Martinez‐Borra;J. C. Torre‐Alonso;S. Gonzalez‐Roces

  • Protective Effect of the HLA-Bw4I80 Epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 Gene against the Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection

    Antonio López-Vázquez;Luis Rodrigo;Jesús Martínez-Borra;Ramón Pérez

  • TNF-α −308A promoter polymorphism is associated with enhanced TNF-α production and inflammatory activity in Crohn’s patients with fistulizing disease

    Segundo González;Luis Rodrigo;Jesús Martínez-Borra;Antonio López-Vázquez

  • NKG2D signaling in cancer immunosurveillance

    Alejandro López-Soto;Leticia Huergo-Zapico;Andrea Acebes-Huerta;Mónica Villa-Alvarez

  • The NKG2D receptor: sensing stressed cells.

    Carlos López-Larrea;Beatriz Suárez-Alvarez;Alejandro López-Soto;Antonio López-Vázquez

  • High serum tumor necrosis factor-α levels are associated with lack of response to infliximab in fistulizing Crohn’s disease

    Jesús Martínez-Borra;Carlos López-Larrea;Segundo González;Dolores Fuentes

  • Chemo-Immunotherapy: A New Trend in Cancer Treatment

    Unknown

  • MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201

    A Lopez-Vazquez;L Rodrigo;D Fuentes;S Riestra

  • HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer.

    A López-Soto;A R Folgueras;E Seto;S Gonzalez

  • Polymorphism in MICA rather than HLA-B/C genes is associated with psoriatic arthritis in the Jewish population.

    Segundo González;Chaim Brautbar;J Martı́nez-Borra;A López-Vazquez

  • Epithelial–Mesenchymal Transition Induces an Antitumor Immune Response Mediated by NKG2D Receptor

    Alejandro López-Soto;Leticia Huergo-Zapico;José Alberto Galván;Luis Rodrigo

  • New insights regarding HLA‐B27 diversity in the Asian population

    S. García‐Fernández;S. Gonzalez;A. Miña Blanco;J. Martinez‐Borra

  • 17β-Estradiol Activates Glucose Uptake via GLUT4 Translocation and PI3K/Akt Signaling Pathway in MCF-7 Cells

    Pablo Garrido;Javier Morán;Ana Alonso;Segundo González

  • Association of ankylosing spondylitis with HLA-B*1403 in a West African population.

    Carlos López-Larrea;Moustafa Mijiyawa;Segundo González;J. Luis Fernández-Morera

  • Interaction between KIR3DL1 and HLA-B*57 supertype alleles influences the progression of HIV-1 infection in a Zambian population.

    A. López-Vázquez;A. Miña-Blanco;J. Martínez-Borra;P.D. Njobvu

  • Prognostic significance of CD8 and CD4 T cells in chronic lymphocytic leukemia

    Ana P Gonzalez-Rodriguez;Juan Contesti;Leticia Huergo-Zapico;Alejandro Lopez-Soto

  • MICA rather than MICB, TNFA, or HLA-DRB1 is associated with susceptibility to psoriatic arthritis.

    Segundo González;Jesús Martínez-Borra;Antonio López-Vázquez;Sonia García-Fernández

  • HLA-B27 alone rather than B27-related class I haplotypes contributes to ankylosing spondylitis susceptibility.

    J Martinez-Borra;Segundo Gonzalez;A López-Vazquez;M.A Gelaz

Frequent Co-Authors

Carlos López-Larrea
Carlos López-Larrea Central University Hospital of Asturias
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Massimo Vitale
Massimo Vitale University of Genoa
Eliecer Coto
Eliecer Coto University of Oviedo
Chaim Brautbar
Chaim Brautbar Hebrew University of Jerusalem
Veronika Groh
Veronika Groh Fred Hutchinson Cancer Research Center
Claudia Cantoni
Claudia Cantoni University of Genoa
Guido Kroemer
Guido Kroemer Université Paris Cité
Thomas Spies
Thomas Spies Fred Hutchinson Cancer Research Center
Manuel S. Rodriguez
Manuel S. Rodriguez Centre national de la recherche scientifique, CNRS

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