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Immunology

D-Index
42
Citations
10854
World Ranking
4872
National Ranking
406

Overview

Salim I. Khakoo is affiliated with the University of Southampton in the United Kingdom. Their work primarily spans the fields of Medicine and Immunology and Microbiology, with significant focus on subfields including Immunology, Epidemiology, Hepatology, Oncology, and Molecular Biology.

Their research focuses on multiple core topics such as Hepatitis C virus research, Immune Cell Function and Interaction, Liver Disease Diagnosis and Treatment, Hepatitis B Virus Studies, T-cell and B-cell Immunology, CAR-T cell therapy research, and Immunotherapy and Immune Responses.

Salim I. Khakoo has published numerous papers across several notable venues. Frequent publication outlets include the Journal of Hepatology, bioRxiv (Cold Spring Harbor Laboratory), Journal of Viral Hepatitis, Frontiers in Immunology, and Frontiers in Oncology.

Recent publications by this scientist cover a range of topics related to hepatology and immune responses in cancer and liver disease:

  • MASLD and the Development of HCC: Pathogenesis and Therapeutic Challenges (2024) in Cancers
  • Natural Killer Cells and Regulatory T Cells Cross Talk in Hepatocellular Carcinoma: Exploring Therapeutic Options for the Next Decade (2021) in Frontiers in Immunology
  • Disruption of the NKG2A:HLA-E Immune Checkpoint Axis to Enhance NK Cell Activation against Cancer (2022) in Vaccines
  • UK-Wide Multicenter Evaluation of Second-line Therapies in Primary Biliary Cholangitis (2022) in Clinical Gastroenterology and Hepatology
  • Identifying the immune interactions underlying HLA class I disease associations (2020) in eLife

Collaboration is a part of their research activities, with frequent co-authors including Tingyan Wang, Theresa Noble, Gail Roadknight, Ben Glampson, and Louise English, each having contributed to at least 17 joint publications.

Best Publications

  • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

    David L. Thomas;Chloe L Thio;Maureen P. Martin;Ying Qi

  • HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection

    Salim I. Khakoo;Chloe L. Thio;Maureen P. Martin;Collin R. Brooks

  • MAIT cells are activated during human viral infections

    B van Wilgenburg;I Scherwitzl;E C Hutchinson;T Leng

  • HIV-1 adaptation to NK-cell-mediated immune pressure

    Galit Alter;David Heckerman;Arne Schneidewind;Lena Fadda

  • KIR and disease: a model system or system of models?

    Salim I. Khakoo;Mary Carrington

  • Rapid Evolution of NK Cell Receptor Systems Demonstrated by Comparison of Chimpanzees and Humans

    Salim I Khakoo;Raja Rajalingam;Benny P Shum;Kristin Weidenbach

  • Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts

    Priya Duggal;Chloe L. Thio;Genevieve L. Wojcik;James J. Goedert

  • Activation of natural killer cells during acute infection with hepatitis C virus.

    Barbara Amadei;Simona Urbani;Angelica Cazaly;Paola Fisicaro

  • Immunotherapy for hepatocellular carcinoma: Current and future.

    Michael P Johnston;Salim I Khakoo

  • Consistent Beneficial Effects of Killer Cell Immunoglobulin-Like Receptor 2DL3 and Group 1 Human Leukocyte Antigen-C Following Exposure to Hepatitis C Virus

    Susanne Knapp;Usama Warshow;Doha Hegazy;Louise Brackenbury

  • The unique profile of cord blood natural killer cells balances incomplete maturation and effective killing function upon activation.

    Martha Luevano;Mehri Daryouzeh;Rehab Alnabhan;Sergio Querol;Sergio Querol

  • Peptide antagonism as a mechanism for NK cell activation.

    Lena Fadda;Gwenoline Borhis;Parvin Ahmed;Kuldeep Cheent

  • Natural killer cells: integrating diversity with function

    Kuldeep Cheent;Salim I. Khakoo

  • Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions

    Salim Khakoo;Paul Glue;Leonie Grellier;Beverley Wells

  • Hanging in the balance: KIR and their role in disease

    Anthony P. Williams;Andrew R. Bateman;Salim I. Khakoo

  • Natural Killer Cell Responses during Viral Infections: Flexibility and Conditioning of Innate Immunity by Experience

    Silvia M Vidal;Salim I Khakoo;Christine A Biron

  • Increased degranulation of natural killer cells during acute HCV correlates with the magnitude of virus-specific T cell responses.

    Sandy Pelletier;Christian Drouin;Nathalie Bédard;Salim I. Khakoo

  • KIR/HLA Interactions and Pathogen Immunity

    Khaleel M. Jamil;Salim I. Khakoo

  • Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

    M A Ansari;E Aranday-Cortes;Ip Clc.;A da Silva Filipe

  • Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes

    Benny P. Shum;Laura R. Flodin;David G. Muir;Raja Rajalingam

  • Natural killer cells and hepatitis C: action and reaction

    Kuldeep Cheent;Salim I Khakoo

  • A Polymorphism in IL28B Distinguishes Exposed, Uninfected Individuals From Spontaneous Resolvers of HCV Infection

    Susanne Knapp;Usama Warshow;K.M. Alexander Ho;Doha Hegazy

Frequent Co-Authors

Graeme J. M. Alexander
Graeme J. M. Alexander University College London
Gregory D. Kirk
Gregory D. Kirk Johns Hopkins University
Chloe L. Thio
Chloe L. Thio Johns Hopkins University
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
David L. Thomas
David L. Thomas Johns Hopkins University
Michael P. Busch
Michael P. Busch University of California, San Francisco
Arthur Y. Kim
Arthur Y. Kim Harvard University
James J. Goedert
James J. Goedert National Institutes of Health
Georg M. Lauer
Georg M. Lauer Harvard University
Mark Thursz
Mark Thursz Imperial College London

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