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Biology and Biochemistry

D-Index
73
Citations
15255
World Ranking
6068
National Ranking
2856

Overview

Trygve O. Tollefsbol is affiliated with the University of Alabama at Birmingham in the United States. Their research spans a broad range of topics primarily within the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine.

The scientist's work is concentrated in several subfields including Molecular Biology, Genetics, Cancer Research, Oncology, and Pathology and Forensic Medicine. Their main research topics encompass:

  • Epigenetics and DNA Methylation
  • Genomics, phytochemicals, and oxidative stress
  • RNA modifications and cancer
  • Nutrition, Genetics, and Disease
  • Gut microbiota and health
  • Diet and metabolism studies
  • Tea Polyphenols and Effects

Tollefsbol has published extensively on subjects related to DNA methylation, epigenetic mechanisms, and the intersection of nutrition and genetics. Some of their recent papers include:

  • "DNA methylation methods: Global DNA methylation and methylomic analyses" (2020), published in Methods
  • "The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes" (2020), published in Frontiers in Genetics
  • "Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition" (2022), published in Experimental Cell Research
  • "The Epigenetic Link between Polyphenols, Aging and Age-Related Diseases" (2020), published in Genes
  • "Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications" (2020), published in Methods

The venues where Trygve O. Tollefsbol frequently publishes include:

  • Nutrients
  • Methods
  • International Journal of Molecular Sciences
  • Scientific Reports
  • Cancer Research

Collaboration is a notable aspect of their research, with frequent co-authors including Shizhao Li, Itika Arora, Manvi Sharma, Huixin Wu, and Yuanyuan Li. These collaborations highlight a diverse research network contributing to studies in epigenetics and related fields.

Best Publications

  • Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT).

    Joseph C Poole;Lucy G Andrews;Trygve O Tollefsbol

  • Epigenetic diet: impact on the epigenome and cancer

    Tabitha M Hardy;Trygve O Tollefsbol

  • The impact of metabolism on DNA methylation

    Clayton L. Ulrey;Liang Liu;Lucy G. Andrews;Trygve O. Tollefsbol

  • Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.

    Syed M. Meeran;Shweta N. Patel;Trygve O. Tollefsbol

  • DNA methylation detection: bisulfite genomic sequencing analysis

    Yuanyuan Li;Trygve O. Tollefsbol

  • Gene-Environment Interactions and Epigenetic Basis of Human Diseases

    Liang Liu;Yuanyuan Li;Trygve O. Tollefsbol

  • Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases

    Bidisha Paul;Stephen Barnes;Wendy Demark-Wahnefried;Casey Morrow

  • Regulation of the human catalytic subunit of telomerase (hTERT).

    Michael Daniel;Gregory W. Peek;Trygve O. Tollefsbol

  • Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components.

    Yuanyuan Li;Trygve O. Tollefsbol

  • Epigenetic targets of bioactive dietary components for cancer prevention and therapy

    Syed M. Meeran;Amiya Ahmed;Trygve O. Tollefsbol

  • Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG

    Joel B. Berletch;Canhui Liu;William K. Love;Lucy G. Andrews

  • Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis.

    Yan Y. Sanders;Annie Pardo;Moisés Selman;Gerard J. Nuovo

  • Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts.

    Mark A. Casillas;Nadejda Lopatina;Lucy G. Andrews;Trygve O. Tollefsbol

  • Aging, cancer and nutrition: the DNA methylation connection

    Liang Liu;Rebecca C. Wylie;Lucy G. Andrews;Trygve O. Tollefsbol

  • EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis.

    Anshu Mittal;Mitchell S Pate;Rebecca C Wylie;Trygve O Tollefsbol

  • Epigenetic regulation of caloric restriction in aging

    Yuanyuan Li;Michael Daniel;Trygve O Tollefsbol

  • Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms.

    Yuanyuan Li;Liang Liu;Lucy G. Andrews;Trygve O. Tollefsbol

  • Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells

    Yuanyuan Li;Yih-Ying Yuan;Syed M Meeran;Trygve O Tollefsbol

  • Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts.

    Nadejda Lopatina;Joyce F. Haskell;Lucy G. Andrews;Joseph C. Poole

  • Polyphenols and Aging

    Brannon L Queen;Trygve O Tollefsbol

Frequent Co-Authors

Harvey J. Cohen
Harvey J. Cohen Duke University
Santosh K. Katiyar
Santosh K. Katiyar University of Alabama at Birmingham
Clyde A. Hutchison
Clyde A. Hutchison J. Craig Venter Institute
Casey D. Morrow
Casey D. Morrow University of Alabama at Birmingham
Stephen Barnes
Stephen Barnes University of Alabama at Birmingham
Ronald D. Alvarez
Ronald D. Alvarez Vanderbilt University Medical Center
Ali Ahmed
Ali Ahmed Georgetown University
Charles N. Landen
Charles N. Landen University of Virginia
James S. Hagood
James S. Hagood University of North Carolina at Chapel Hill
Toshikazu Ushijima
Toshikazu Ushijima National Cancer Centre

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