World's Best Scientists 2026 revealed!

Overview

Charles N. Landen is affiliated with the University of Virginia in the United States and has contributed extensively to research in medicine, particularly in ovarian cancer. Their work spans several subfields including molecular biology, reproductive medicine, oncology, cancer research, and obstetrics and gynecology. A significant portion of their publications focuses on ovarian cancer diagnosis and treatment, with related topics including PARP inhibition in cancer therapy, galectins and cancer biology, protein tyrosine phosphatases, microRNA in disease regulation, intraperitoneal and appendiceal malignancies, and angiogenesis and VEGF in cancer.

Among recent scholarly publications by Charles N. Landen are:

  • Influence of Genomic Landscape on Cancer Immunotherapy for Newly Diagnosed Ovarian Cancer: Biomarker Analyses from the IMagyn050 Randomized Clinical Trial, 2023, Clinical Cancer Research
  • CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer, 2021, Cancers
  • A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer, 2021, Cells
  • Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer, 2021, Biomolecules
  • Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles, 2023, Nature Communications

Frequent coauthors collaborating with Landen include:

  • Kathleen N. Moore
  • Michael A. Bookman
  • Danielle C. Llaneza
  • Ronald J. Buckanovich
  • Luciana Molinero

Charles N. Landen has published repeatedly in several scientific venues, with notable frequency in:

  • Gynecologic Oncology
  • Clinical Cancer Research
  • Journal of Clinical Oncology
  • Gynecologic Oncology Reports
  • Cancer Research

Their scientific output is grounded predominantly in the fields of medicine, alongside biochemistry, genetics, and molecular biology. The extensive focus on ovarian cancer and related molecular pathways illustrates a significant engagement with both fundamental and applied aspects of cancer biology and treatment research.

Best Publications

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma

    Premal H Thaker;Liz Y Han;Aparna A Kamat;Jesusa M Arevalo

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Therapeutic EphA2 Gene Targeting In vivo Using Neutral Liposomal Small Interfering RNA Delivery

    Charles N. Landen;Arturo Chavez-Reyes;Corazon Bucana;Rosemarie Schmandt

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Paraneoplastic Thrombocytosis in Ovarian Cancer

    Rebecca L. Stone;Alpa M. Nick;Iain A. McNeish;Frances Balkwill

  • Stress hormone-mediated invasion of ovarian cancer cells.

    Anil K. Sood;Robert Bhatty;Aparna A. Kamat;Charles N. Landen

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Early Events in the Pathogenesis of Epithelial Ovarian Cancer

    Charles N. Landen;Michael J. Birrer;Anil K. Sood

  • Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer

    Charles N. Landen;Blake Goodman;Ashwini A. Katre;Adam D. Steg;Adam D. Steg

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

    Adam D. Steg;Kerri S. Bevis;Ashwini A. Katre;Angela Ziebarth

  • In vivo gene therapy of hemophilia B: sustained partial correction in factor IX-deficient dogs

    Mark A. Kay;Steven Rothenberg;Charles N. Landen;Dwight A. Bellinger

  • Focal Adhesion Kinase Targeting Using In vivo Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy

    Jyotsnabaran Halder;Aparna A. Kamat;Charles N. Landen;Liz Y. Han

  • The role of the fallopian tube in the origin of ovarian cancer

    Britt K. Erickson;Michael G. Conner;Charles N. Landen

  • Effect of Interleukin-8 Gene Silencing With Liposome-Encapsulated Small Interfering RNA on Ovarian Cancer Cell Growth

    William M. Merritt;Yvonne G. Lin;Whitney A. Spannuth;Mavis S. Fletcher

  • In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs

    Mark A. Kay;Mark A. Kay;Charles N. Landen;Steven R. Rothenberg;Lesli A. Taylor

  • EphA2 expression is associated with aggressive features in ovarian carcinoma

    Premal H. Thaker;Michael Deavers;Joseph Celestino;Angela Thornton

Frequent Co-Authors

Anil K. Sood
Anil K. Sood The University of Texas MD Anderson Cancer Center
Ronald D. Alvarez
Ronald D. Alvarez Vanderbilt University Medical Center
David M. Gershenson
David M. Gershenson The University of Texas MD Anderson Cancer Center
Robert L. Coleman
Robert L. Coleman The University of Texas MD Anderson Cancer Center
Gabriel Lopez-Berestein
Gabriel Lopez-Berestein The University of Texas MD Anderson Cancer Center
Susan K. Lutgendorf
Susan K. Lutgendorf University of Iowa
William E. Grizzle
William E. Grizzle University of Alabama at Birmingham
Russell Broaddus
Russell Broaddus University of North Carolina at Chapel Hill
Christina Yau
Christina Yau University of California, San Francisco
Maciej Wiznerowicz
Maciej Wiznerowicz Poznan University of Medical Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in healthcare doesn't always mean following the traditional path to becoming a doctor. There are a variety of alternative online programs and flexible careers available for those interested in the medical field. For non-nurses seeking an advanced nursing credential, direct msn programs online offer a streamlined route to a Master of Science in Nursing, opening doors to advanced practice roles.

If you’re just starting out, adn programs provide a quicker pathway into nursing, typically requiring only two years of study. Similarly, aspiring nurses who want to avoid lengthy exam processes can consider an lpn program without teas test as an entry point into the field.

For those interested in non-clinical roles, accredited medical billing and coding schools with financial aid offer career-focused training with support for tuition costs. These programs make healthcare careers more accessible and flexible for students from all backgrounds.

Best Scientists Citing Charles N. Landen

Trending Scientists