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Biology and Biochemistry

D-Index
54
Citations
9644
World Ranking
15712
National Ranking
6546

Overview

James S. Hagood is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on Pulmonary and Respiratory Medicine. They have contributed extensively to subfields such as Molecular Biology, Epidemiology, Surgery, and Pediatrics, Perinatology and Child Health.

The scientist's work spans several main topics, notably:

  • Neonatal Respiratory Health Research
  • Congenital Diaphragmatic Hernia Studies
  • Single-cell and spatial transcriptomics
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Tracheal and airway disorders
  • Respiratory viral infections research
  • Cell Adhesion Molecules Research

James S. Hagood has published in multiple venues, with frequent publications found in:

  • Pediatric Pulmonology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • American Journal of Respiratory and Critical Care Medicine
  • Nature Cell Biology

Key recent papers include:

  • "An integrated cell atlas of the lung in health and disease," 2023, Nature Medicine
  • "Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)," 2023, Nature Cell Biology
  • "SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice," 2022, Science Translational Medicine
  • "Therapeutic Use of Extracellular Vesicles for Acute and Chronic Lung Disease," 2020, International Journal of Molecular Sciences
  • "Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface," 2020, Journal of Clinical Investigation

The scientist has collaborated frequently with colleagues such as William A. Gower, Kenichi Okuda, Richard C. Boucher, Hong Dang, and Raymond J. Pickles. These collaborations have resulted in multiple co-authored publications, demonstrating interdisciplinary connections within pulmonary medicine and molecular biology.

Best Publications

  • Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis

    Tanya A. Rege;James S. Hagood

  • An Official American Thoracic Society Clinical Practice Guideline: Classification, Evaluation, and Management of Childhood Interstitial Lung Disease in Infancy

    Geoffrey Kurland;Robin R. Deterding;James S. Hagood;Lisa R. Young

  • Matrix Metalloproteinases as Therapeutic Targets for Idiopathic Pulmonary Fibrosis

    Vanessa J. Craig;Vanessa J. Craig;Li Zhang;James S. Hagood;James S. Hagood;Caroline A. Owen;Caroline A. Owen

  • STAT3 Acts as a Co-activator of Glucocorticoid Receptor Signaling

    Zhixin Zhang;Simon Jones;James S. Hagood;Nelson L. Fuentes

  • Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.

    Timothy S. Blackwell;Andrew M. Tager;Zea Borok;Bethany B. Moore

  • Loss of Fibroblast Thy-1 Expression Correlates with Lung Fibrogenesis

    James S. Hagood;Priya Prabhakaran;Pallavi Kumbla;Lorena Salazar

  • Emerging Concepts in the Pathogenesis of Lung Fibrosis

    William D. Hardie;Stephan W. Glasser;James S. Hagood

  • Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis.

    Yan Y. Sanders;Annie Pardo;Moisés Selman;Gerard J. Nuovo

  • Extracellular matrix in lung development, homeostasis and disease

    Yong Zhou;Jeffrey C. Horowitz;Alexandra Naba;Namasivayam Ambalavanan

  • Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses.

    Tanya A. Rege;James S. Hagood

  • Altered DNA methylation profile in idiopathic pulmonary fibrosis.

    Yan Y. Sanders;Namasivayam Ambalavanan;Brian Halloran;Xiangyu Zhang

  • The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

    Michael P. Snyder;Shin Lin

  • Myofibroblast differentiation and survival in fibrotic disease.

    Kornelia Kis;Xiaoqiu Liu;James S. Hagood

  • LungMAP: The Molecular Atlas of Lung Development Program

    Maryanne E. Ardini-Poleske;Robert Fred Clark;Charles Ansong;James P Carson

  • Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates.

    Xiao Li;T Prescott Atkinson;James Hagood;Chris Makris

  • Enhanced Myofibroblastic Differentiation and Survival in Thy-1(−) Lung Fibroblasts

    Yan Y. Sanders;Pallavi Kumbla;James S. Hagood

  • Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.

    Yan Y Sanders;James S Hagood;James S Hagood;Hui Liu;Wei Zhang

  • Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype

    John E. Bradley;Gustavo Ramirez;James S. Hagood

  • Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts

    Rui-Ming Liu;Jinah Choi;Jian-He Wu;Kimberly A. Gaston Pravia

  • Thy-1 Expression Regulates the Ability of Rat Lung Fibroblasts to Activate Transforming Growth Factor-β in Response to Fibrogenic Stimuli

    Yong Zhou;James S. Hagood;Joanne E. Murphy-Ullrich

Frequent Co-Authors

Namasivayam Ambalavanan
Namasivayam Ambalavanan University of Alabama at Birmingham
Moisés Selman
Moisés Selman National Autonomous University of Mexico
Annie Pardo
Annie Pardo National Autonomous University of Mexico
Joanne E. Murphy-Ullrich
Joanne E. Murphy-Ullrich University of Alabama at Birmingham
Naftali Kaminski
Naftali Kaminski Yale University
Ziv Bar-Joseph
Ziv Bar-Joseph Carnegie Mellon University
Victor J. Thannickal
Victor J. Thannickal Tulane University
Eric S. White
Eric S. White University of Michigan–Ann Arbor
Trygve O. Tollefsbol
Trygve O. Tollefsbol University of Alabama at Birmingham
jeffrey a whitsett
jeffrey a whitsett Cincinnati Children's Hospital Medical Center

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