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Roderick H. Dashwood

Roderick H. Dashwood

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
18508
World Ranking
4170
National Ranking
2042

Overview

Roderick H. Dashwood is affiliated with Texas A&M University in the United States. Their research spans key areas within Biochemistry, Genetics and Molecular Biology as well as Medicine, with a total of 56 and 45 publications respectively in these fields. Within these disciplines, they focus on subfields including Molecular Biology, Oncology, Pathology and Forensic Medicine, Pulmonary and Respiratory Medicine, and Surgery.

The scientific work of Roderick H. Dashwood covers several important topics in cancer research and related biomedical sciences. Main areas of study include Colorectal Cancer Treatments and Studies, Protein Degradation and Inhibitors, Histone Deacetylase Inhibitors Research, Epigenetics and DNA Methylation, Genetic factors in colorectal cancer, Cancer Immunotherapy and Biomarkers, and Gut microbiota and health.

Roderick H. Dashwood has contributed research published in a variety of notable scientific journals. Frequent publication venues where their work appears include Cancer Research, Journal of Cancer Prevention, Cancer Prevention Research, Cancers, and Nutrients.

Recent papers demonstrate the breadth of their research focus:

  • "Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals" (2020), published in Antioxidants
  • "Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma" (2020), published in Science Advances
  • "Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7" (2022), published in Frontiers in Immunology
  • "Emerging crosstalk between long non-coding RNAs and Nrf2 signaling" (2020), published in Cancer Letters
  • "Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics" (2021), published in Gut Microbes

Collaborations form a significant part of Roderick H. Dashwood's research activities. Frequent co-authors include Praveen Rajendran, Sabeeta Kapoor, Wan Mohaiza Dashwood, Jorge Enrique Tovar Perez, and Altaf Mohammed.

Best Publications

  • Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

    Jane V. Higdon;Barbara Delage;David E. Williams;Roderick H. Dashwood

  • Multi-targeted prevention of cancer by sulforaphane.

    John D. Clarke;Roderick H. Dashwood;Emily Ho

  • A Novel Mechanism of Chemoprotection by Sulforaphane: Inhibition of Histone Deacetylase

    Melinda C. Myzak;P. Andrew Karplus;Fung-Lung Chung;Roderick H. Dashwood

  • Protection of conjugated linoleic acids against 2-amino-3- methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms.

    C. Liew;H.A.J Schut;S.F. Chin;M.W. Pariza

  • Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice

    Melinda C. Myzak;W. Mohaiza Dashwood;Gayle A. Orner;Emily Ho

  • Sulforaphane Retards the Growth of Human PC-3 Xenografts and Inhibits HDAC Activity in Human Subjects

    Melinda C. Myzak;Philip Tong;Wan-Mohaiza Dashwood;Roderick H. Dashwood

  • Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells

    Melinda C. Myzak;Karin Hardin;Rong Wang;Roderick H. Dashwood

  • Concentration and photochemistry of PAHs, NPAHs, and OPAHs and toxicity of PM2.5 during the Beijing Olympic Games.

    Wentao Wang;Narumol Jariyasopit;Jill Schrlau;Yuling Jia

  • Dietary histone deacetylase inhibitors: from cells to mice to man.

    Roderick H. Dashwood;Emily Ho

  • Dietary Sulforaphane, a Histone Deacetylase Inhibitor for Cancer Prevention

    Emily Ho;John D. Clarke;Roderick H. Dashwood

  • Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay

    Gilberto Santana-Rios;Gayle A. Orner;Adams Amantana;Cynthia Provost

  • Chemoprotection by sulforaphane: Keep one eye beyond Keap1

    Melinda C. Myzak;Roderick H. Dashwood

  • Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?

    Roderick H. Dashwood;Melinda C. Myzak;Emily Ho

  • Dietary Phytochemicals, HDAC Inhibition, and DNA Damage/Repair Defects in Cancer Cells

    Praveen Rajendran;Emily Ho;David E Williams;Roderick H Dashwood

  • Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds

    Hui Nian;Barbara Delage;Emily Ho;Roderick H. Dashwood

  • Endurance exercise results in DNA damage as detected by the comet assay.

    Angela Mastaloudis;Tian-Wei Yu;Robert P. O'Donnell;Robert P. O'Donnell;Balz Frei

  • Histone Deacetylases as Targets for Dietary Cancer Preventive Agents: Lessons Learned with Butyrate, Diallyl Disulfide, and Sulforaphane

    Melinda C Myzak;Roderick H Dashwood

  • Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables?

    Roderick H Dashwood

  • MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION: Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f]quinoline-induced DNA adducts and colonic aberrant crypts in the F344 rat

    M. Xu;A.C. Bailey;J.F. Hernaez;C.R. Taoka

  • Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.

    John D. Clarke;Anna Hsu;Zhen Yu;Roderick H. Dashwood

Frequent Co-Authors

David E. Williams
David E. Williams Oregon State University
Emily Ho
Emily Ho Oregon State University
Jan F. Stevens
Jan F. Stevens Oregon State University
Asif Rashid
Asif Rashid The University of Texas MD Anderson Cancer Center
Jeff H. Chang
Jeff H. Chang Oregon State University
Hitoshi Nakagama
Hitoshi Nakagama National Cancer Research Institute, UK
Yingzi Cong
Yingzi Cong The University of Texas Medical Branch at Galveston
Tor C. Savidge
Tor C. Savidge Baylor College of Medicine
Stephen T. Talcott
Stephen T. Talcott Texas A&M University
Staci L. Massey Simonich
Staci L. Massey Simonich Oregon State University

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