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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
14560
World Ranking
8724
National Ranking
22

Overview

Richard Mithen is affiliated with the University of Auckland in New Zealand. Their research primarily focuses on biochemistry, genetics, and molecular biology, with notable contributions in medicine. Within these fields, key subfields addressed include molecular biology, plant science, nutrition and dietetics, pharmacology, and physiology.

The scientist's main research topics cover a range of areas such as genomics, phytochemicals, and oxidative stress, Piperaceae chemical and biological studies, nutritional studies and diet, diet and metabolism studies, effects of nitrogen and sulfur on Brassica, epigenetics and DNA methylation, and microRNA in disease regulation.

Recent publications by Richard Mithen include:

  • "Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review" (2021), International Journal of Molecular Sciences
  • "Microbiomes of Urine and the Prostate Are Linked to Human Prostate Cancer Risk Groups" (2022), European Urology Oncology
  • "CRISPR-Cas9-Mediated Gene Editing of MYB28 Genes Impair Glucoraphanin Accumulation of Brassica oleracea in the Field" (2021), The CRISPR Journal
  • "Accumulation of Sulforaphane and Alliin in Human Prostate Tissue" (2022), Nutrients
  • "Effects of in vitro metabolism of a broccoli leachate, glucosinolates and S-methylcysteine sulphoxide on the human faecal microbiome" (2020), European Journal of Nutrition

Frequent publication venues where Richard Mithen has contributed multiple works include:

  • Nutrients
  • Proceedings of The Nutrition Society
  • Journal of Nutrition
  • Molecular Nutrition & Food Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Among their frequent coauthors are Farha Ramzan, Μαρία Τράκα, Perla Troncoso-Rey, Shikha Saha, and Meika Foster, with multiple collaborations documented across various studies.

Best Publications

  • Molecular basis for chemoprevention by sulforaphane: a comprehensive review.

    N. Juge;R. F. Mithen;M. Traka

  • Glucosinolates in Brassica Vegetables - the Influence of the Food Supply Chain on Intake, Bioavailability and Human Health

    Ruud Verkerk;Monika Schreiner;Angelika Krumbein;Ewa Ciska

  • The nutritional significance, biosynthesis and bioavailability of glucosinolates in human foods

    Richard F Mithen;Matthijs Dekker;Ruud Verkerk;Sylvie Rabot

  • Glucosinolates, isothiocyanates and human health

    Maria Traka;Richard Mithen

  • Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

    Colin S Cooper;Colin S Cooper;Rosalind Eeles;Rosalind Eeles;David C Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • The effect of modifying the glucosinolate content of leaves of oilseed rape (Brassica napus ssp. oleifera) on its interaction with specialist and generalist pests

    A. Giamoustaris;R. Mithen

  • Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli

    Amy V Gasper;Ahmed Al-janobi;Julie A Smith;James R Bacon

  • Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

    Y S Ju;L B Alexandrov;M Gerstung;I Martincorena

  • The use of AFLP fingerprinting for the detection of genetic variation in fungi

    Dorothea Majer;Richard Mithen;Brian G. Lewis;Pieter Vos

  • Development of isothiocyanate-enriched broccoli, and its enhanced ability to induce phase 2 detoxification enzymes in mammalian cells

    R. Mithen;K. Faulkner;R. Magrath;P. Rose

  • Glucosinolates – biochemistry, genetics and biological activity

    Richard Mithen

  • Epithiospecifier Protein from Broccoli (Brassica oleracea L. ssp. italica) Inhibits Formation of the Anticancer Agent Sulforaphane

    Nathan V. Matusheski;Ranjan Swarup;John A. Juvik;Richard Mithen

  • Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli.

    Kathy Faulkner;Richard Mithen;Gary Williamson

  • Leaf glucosinolate profiles and their relationship to pest and disease resistance in oilseed rape

    Richard Mithen

  • Growth and mortality of individual plants as a function of "available area".

    Richard Mithen;John L. Harper;Jacob Weiner

  • Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells

    Jana Jakubíková;Ján Sedlák;Richard Mithen;Yongping Bao;Yongping Bao

  • Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate

    Maria Traka;Amy V. Gasper;Antonietta Melchini;Antonietta Melchini;James R. Bacon

  • 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes

    Peter Rose;Kathy Faulkner;Gary Williamson;Richard Mithen

  • Diurnal and light regulation of sulphur assimilation and glucosinolate biosynthesis in Arabidopsis

    Stine Huseby;Anna Koprivova;Bok-Rye Lee;Bok-Rye Lee;Shikha Saha

  • In vitro activity of glucosinolates and their products against Leptosphaeria maculans

    R.F. Mithen;B.G. Lewis;G.R. Fenwick

Frequent Co-Authors

David A. Barrett
David A. Barrett University of Nottingham
Arjan Narbad
Arjan Narbad Norwich Research Park
Gary Williamson
Gary Williamson Monash University
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Ian T. Johnson
Ian T. Johnson Norwich Research Park
Christopher J. Hawkey
Christopher J. Hawkey University of Nottingham
Ian Clark
Ian Clark Rothamsted Research
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research
Caroline Dean
Caroline Dean John Innes Centre
Paul C. Boutros
Paul C. Boutros University of California, Los Angeles

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