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Microbiology

D-Index
75
Citations
19439
World Ranking
1505
National Ranking
124

Overview

Ian Clark is a researcher affiliated with Rothamsted Research in the United Kingdom, specializing in the field of Biochemistry, Genetics and Molecular Biology. Their work predominantly focuses on Cancer Research and Molecular Biology, with additional involvement in Rheumatology, Oncology, and Public Health, Environmental and Occupational Health.

Their research topics cover a range of areas related to molecular and cellular mechanisms, including:

  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Osteoarthritis Treatment and Mechanisms
  • Genomics, phytochemicals, and oxidative stress
  • RNA Research and Splicing
  • Bone Metabolism and Diseases

Ian Clark has published extensively, contributing to several frequent publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • International Journal of Molecular Sciences
  • eLife
  • RNA

Some of the recent papers authored or coauthored by Ian Clark include:

  • MicroRNA-Based Diagnosis and Therapy, 2022, International Journal of Molecular Sciences
  • microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs, 2020, RNA
  • HDAC6 regulates NF-κB signalling to control chondrocyte IL-1-induced MMP and inflammatory gene expression, 2022, Scientific Reports
  • The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer's Disease, 2022, International Journal of Molecular Sciences
  • TimiRGeN: R/Bioconductor package for time series microRNA-mRNA integration and analysis, 2021, Bioinformatics

Their frequent collaborators include:

  • David A. Young
  • Matt J. Barter
  • Jamie Soul
  • T.E. Swingler
  • Katarzyna A. Piróg

Best Publications

  • The ADAMTS metalloproteinases.

    Sarah Porter;Ian M. Clark;Lara Kevorkian;Dylan R. Edwards

  • Land use driven change in soil pH affects microbial carbon cycling processes

    Ashish A. Malik;Jeremy Puissant;Kate M. Buckeridge;Tim Goodall

  • Soil pH Determines Microbial Diversity and Composition in the Park Grass Experiment

    Kateryna Zhalnina;Raquel Dias;Patricia Dörr de Quadros;Patricia Dörr de Quadros;Austin Davis-Richardson

  • The regulation of matrix metalloproteinases and their inhibitors

    Ian M. Clark;Tracey E. Swingler;Clara L. Sampieri;Dylan R. Edwards

  • The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells

    Lee Tuddenham;Guy Wheeler;Sofia Ntounia-Fousara;Jasmine Waters

  • Expression profiling of metalloproteinases and their inhibitors in cartilage.

    Lara Kevorkian;David A. Young;Clare Darrah;Simon T. Donell

  • Hypoxia promotes fibrogenesis in human renal fibroblasts.

    Jill T. Norman;Ian M. Clark;Patricia L. Garcia

  • The role of chondrocyte senescence in osteoarthritis

    Jo S. Price;Jasmine G. Waters;Clare Darrah;Caroline Pennington

  • Matrix metalloproteinases in arthritic disease.

    Gillian Murphy;Vera Knäuper;Susan Atkinson;George Butler

  • Controls on soil nitrogen cycling and microbial community composition across land use and incubation temperature

    W. R. Cookson;M. Osman;P. Marschner;D. A. Abaye

  • Accessing the soil metagenome for studies of microbial diversity.

    Tom O. Delmont;Patrick Robe;Sébastien Cecillon;Ian M. Clark

  • Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.

    Rose K Davidson;Jasmine G Waters;Lara Kevorkian;Clare Darrah

  • Culture-independent molecular techniques for soil microbial ecology

    Penny R. Hirsch;Tim H. Mauchline;Ian M. Clark

  • The expression and function of microRNAs in chondrogenesis and osteoarthritis.

    Tracey E Swingler;Guy Wheeler;Virginia Carmont;Hannah R Elliott

  • Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease

    Jenny L Scott;Christos Gabrielides;Rose K Davidson;Tracey E Swingler

  • Metatranscriptomic census of active protists in soils.

    Stefan Geisen;Alexander T Tveit;Ian M Clark;Andreas Richter

  • The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: A time‐course study using real‐time quantitative reverse transcription–polymerase chain reaction

    P. J. T. Koshy;C. J. Lundy;A. D. Rowan;S. Porter

  • Structure, Fluctuation and Magnitude of a Natural Grassland Soil Metagenome

    Tom O Delmont;Emmanuel Prestat;Kevin P Keegan;Michael Faubladier;Michael Faubladier

  • Data analysis for 16S microbial profiling from different benchtop sequencing platforms.

    Victor S. Pylro;Victor S. Pylro;Luiz Fernando W. Roesch;Daniel K. Morais;Daniel K. Morais;Ian M. Clark

  • The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

    T. E. Cawston;V. A. Curry;C. A. Summers;I. M. Clark

  • Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours.

    Robert E. Hewitt;Iain H. Leach;Desmond G. Powe;Ian M. Clark

Frequent Co-Authors

Penny R. Hirsch
Penny R. Hirsch Rothamsted Research
Tim E. Cawston
Tim E. Cawston Newcastle University
Dylan R. Edwards
Dylan R. Edwards University of East Anglia
Brian R. Kerry
Brian R. Kerry Rothamsted Research
Steve P. McGrath
Steve P. McGrath Rothamsted Research
Tamas Dalmay
Tamas Dalmay University of East Anglia
Andrew D. Rowan
Andrew D. Rowan Newcastle University
Aedin Cassidy
Aedin Cassidy Queen's University Belfast
Jizhong Zhou
Jizhong Zhou University of Oklahoma
Alex J. MacGregor
Alex J. MacGregor University of East Anglia

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