Molecular biology, Diindolylmethane, 3,3'-Diindolylmethane, Biochemistry and Cancer cell are his primary areas of study. His Molecular biology research is multidisciplinary, incorporating elements of Transfection, Receptor and Promoter, Response element, Sp1 transcription factor. His 3,3'-Diindolylmethane research includes elements of Kinase and Mitochondrion.
His Biochemistry study typically links adjacent topics like Guinea pig. Leonard F. Bjeldanes interconnects Cancer research, Cell growth and Cyclin-dependent kinase, Cell cycle, Apoptosis in the investigation of issues within Cancer cell. His Estrogen receptor research is multidisciplinary, relying on both Endocrinology and Cyclin-dependent kinase 6.
His primary areas of study are Biochemistry, Cancer research, Internal medicine, Endocrinology and 3,3'-Diindolylmethane. Biochemistry and Anticarcinogen are commonly linked in his work. The various areas that Leonard F. Bjeldanes examines in his Cancer research study include Cell growth, Cancer cell, Cyclin-dependent kinase, Signal transduction and Estrogen receptor.
In his study, which falls under the umbrella issue of Estrogen receptor, Pharmacology is strongly linked to Agonist. His study in 3,3'-Diindolylmethane is interdisciplinary in nature, drawing from both Molecular biology, Angiogenesis and Diindolylmethane. His studies in Molecular biology integrate themes in fields like Receptor, Endogeny and Cell culture, Transfection.
Leonard F. Bjeldanes mainly focuses on Cancer research, Cancer cell, 3,3'-Diindolylmethane, Biochemistry and Indole-3-carbinol. His studies deal with areas such as Endocrinology, Internal medicine, Signal transduction and Estrogen receptor, Estrogen receptor alpha as well as Cancer research. The Internal medicine study combines topics in areas such as Cell growth and Phosphorylation.
His research integrates issues of Cell cycle, Kinase and Transfection in his study of Cancer cell. He has included themes like Angiogenesis, Diindolylmethane and Immunology, Interferon gamma, Cytokine in his 3,3'-Diindolylmethane study. His work carried out in the field of Biochemistry brings together such families of science as Luciferase and Aspergillus insulicola.
The scientist’s investigation covers issues in Cancer research, Cell biology, Biochemistry, Estrogen receptor alpha and Indole-3-carbinol. Leonard F. Bjeldanes combines subjects such as Cell cycle checkpoint, Cell cycle, CDK inhibitor, Diindolylmethane and 3,3'-Diindolylmethane with his study of Cancer research. In his work, Cancer cell is strongly intertwined with MAPK/ERK pathway, which is a subfield of Cell cycle checkpoint.
His Cell biology research incorporates themes from Molecular biology and Estrogen receptor beta. He has researched Biochemistry in several fields, including Combinatorial chemistry and Tumor cells. His p38 mitogen-activated protein kinases research integrates issues from Carcinogenesis, Endocrinology and Internal medicine.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Leonard F. Bjeldanes;Jin-Young Kim;Karl R. Grose;James C. Bartholomew.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Indole-3-carbinol Inhibits the Expression of Cyclin-dependent Kinase-6 and Induces a G1 Cell Cycle Arrest of Human Breast Cancer Cells Independent of Estrogen Receptor Signaling
Carolyn M. Cover;S. Jean Hsieh;Susan H. Tran;Gunnell Hallden.
Journal of Biological Chemistry (1998)
Lipoxin A4: a new class of ligand for the Ah receptor.
C. M. Schaldach;Jacques Riby;Leonard F. Bjeldanes.
Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells.
Chibo Hong;Gary L. Firestone;Leonard F. Bjeldanes.
Biochemical Pharmacology (2002)
Identification of the mutagens in cooked beef.
James S. Felton;Mark G. Knize;Nancy H. Shen;Brian D. Andresen.
Environmental Health Perspectives (1986)
Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
Ichen Chen;Stephen Safe;Leonard Bjeldanes.
Biochemical Pharmacology (1996)
Oligomerization of indole-3-carbinol in aqueous acid.
Karl R. Grose;Leonard F. Bjeldanes.
Chemical Research in Toxicology (1992)
Plant-derived 3,3′-Diindolylmethane Is a Strong Androgen Antagonist in Human Prostate Cancer Cells
Hien T. Le;Charlene M. Schaldach;Gary L. Firestone;Leonard F. Bjeldanes.
Journal of Biological Chemistry (2003)
Isolation and characterization of new mutagens from fried ground beef.
J. S. Felton;M. G. Knize;C. Wood;B. J. Wuebbles.
3,3'-Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21WAF1/CIP1 expression
Chibo Hong;Hyeon.-A. Kim;Gary L. Firestone;Leonard F. Bjeldanes.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: