What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Receptor, Biochemistry, Molecular biology, Prostaglandin E2 receptor and Cell biology.
His study of G protein-coupled receptor is a part of Receptor.
His G protein-coupled receptor research is multidisciplinary, incorporating perspectives in PELP-1 and Immune receptor.
The study incorporates disciplines such as 5-HT5A receptor, Interleukin 5 receptor alpha subunit, Transfection and Interleukin 10 receptor, alpha subunit in addition to Molecular biology.
John W. Regan has included themes like Ophthalmology, Trabecular meshwork and Glaucoma in his Cell biology study.
His Phosphorylation research incorporates elements of Internal medicine and Endocrinology.
His most cited work include:
- Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor (718 citations)
- Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity (681 citations)
- Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype (401 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Receptor, Biochemistry, Cell biology, Molecular biology and Endocrinology.
His research integrates issues of Signal transduction and Prostaglandin in his study of Receptor.
In Cell biology, John W. Regan works on issues like EP4 Receptor, which are connected to CREB and MAPK/ERK pathway.
His Molecular biology research integrates issues from Alpha, Gene expression, Complementary DNA, Protein kinase C and Gene isoform.
While the research belongs to areas of Endocrinology, John W. Regan spends his time largely on the problem of Internal medicine, intersecting his research to questions surrounding Messenger RNA.
His research investigates the link between Adenylyl cyclase and topics such as G protein that cross with problems in Adrenergic receptor.
He most often published in these fields:
- Receptor (64.63%)
- Biochemistry (31.71%)
- Cell biology (29.27%)
What were the highlights of his more recent work (between 2005-2021)?
- Receptor (64.63%)
- Cell biology (29.27%)
- Prostanoid (17.07%)
In recent papers he was focusing on the following fields of study:
John W. Regan focuses on Receptor, Cell biology, Prostanoid, Signal transduction and Internal medicine.
His work carried out in the field of Receptor brings together such families of science as Prostaglandin E, Prostaglandin and Kinase.
Prostaglandin is a subfield of Biochemistry that John W. Regan studies.
The various areas that John W. Regan examines in his Cell biology study include HEK 293 cells, Downregulation and upregulation and EP4 Receptor.
His studies in Signal transduction integrate themes in fields like Molecular biology, Epidermal growth factor, Smooth muscle and Transactivation.
His Internal medicine research incorporates elements of Endocrinology, Ciliary body and Blot.
Between 2005 and 2021, his most popular works were:
- Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. (335 citations)
- EP(4) prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein. (100 citations)
- The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. (75 citations)
In his most recent research, the most cited papers focused on:
John W. Regan mostly deals with Receptor, Signal transduction, Prostanoid, Cell biology and Internal medicine.
His Receptor study necessitates a more in-depth grasp of Biochemistry.
His Signal transduction research is multidisciplinary, relying on both Molecular biology and Cancer research.
In his research, Smooth muscle contraction, Kidney metabolism, Gene isoform and Pertussis toxin is intimately related to Phosphorylation, which falls under the overarching field of Molecular biology.
John W. Regan combines subjects such as Prostaglandin E, Phospholipid, Fatty acid and Arachidonic acid with his study of Prostanoid.
His Internal medicine study which covers Endocrinology that intersects with Epidermal growth factor.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
