World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
14583
World Ranking
12405
National Ranking
5312

Overview

John W. Regan is affiliated with the University of Arizona in the United States. Their research spans several scientific disciplines, primarily focusing on biochemistry, genetics, molecular biology, and medicine. Regan's body of work includes 20 publications in the broader field of Biochemistry, Genetics, and Molecular Biology and 17 publications categorized under Medicine.

The scientist's subfields of study highlight a diverse specialization, including Pharmacology, Genetics, Biochemistry, Astronomy and Astrophysics, and Psychiatry and Mental Health. Regan's research topics are notably varied and cover areas such as inflammatory mediators and NSAID effects, estrogen and related hormone effects, eicosanoids and hypertension pharmacology, intensive care unit cognitive disorders, dementia and cognitive impairment research, aging and gerontology research, and receptor mechanisms and signaling.

Regan has authored and co-authored several research papers, some of which are recognized across multiple academic venues. Notable recent publications include:

  • Astrophysics with the Laser Interferometer Space Antenna, 2022, arXiv (Cornell University)
  • 15-Keto-PGE2 acts as a biased/partial agonist to terminate PGE2-evoked signaling, 2020, Journal of Biological Chemistry
  • Reducing fear and avoidance of memory loss improves mood and social engagement in community-based older adults: a randomized trial, 2023, BMC Geriatrics
  • Validation of the Fear and Avoidance of Memory Loss scale in community-based older adults, 2023, Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring
  • Astrophysics with the Laser Interferometer Space Antenna, 2023, Living Reviews in Relativity

The frequent publication venues for Regan's work include the Proceedings for Annual Meeting of The Japanese Pharmacological Society (6 publications), arXiv (Cornell University) (3 publications), Journal of Biological Chemistry (2 publications), BMC Geriatrics, and Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring.

Regan collaborates regularly with several researchers, highlighting ongoing partnerships and multidisciplinary research efforts. The scientist's frequent co-authors are:

  • Keijo Fukushima (10 collaborative works)
  • Hiromichi Fujino (10 collaborative works)
  • Kanaho Senoo (8 collaborative works)
  • Suzu Endo (4 collaborative works)
  • Masato Mashimo (4 collaborative works)

Best Publications

  • Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

    Brian K. Kobilka;Tong Sun Kobilka;Kiefer Daniel;John W. Regan

  • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

    B. K. Kobilka;H. Matsui;T. S. Kobilka;T. L. Yang-Feng

  • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype

    J W Regan;T S Kobilka;T L Yang-Feng;M G Caron

  • EP2 and EP4 prostanoid receptor signaling.

    John W Regan

  • Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling.

    B F O'Dowd;M Hnatowich;J W Regan;W M Leader

  • Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.

    Masayuki Wada;Cynthia J. DeLong;Yu H. Hong;Caroline J. Rieke

  • Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

    J W Regan;T J Bailey;D J Pepperl;K L Pierce

  • Phosphorylation of Glycogen Synthase Kinase-3 and Stimulation of T-cell Factor Signaling following Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2

    Hiromichi Fujino;Kimberly A. West;John W. Regan

  • Prostaglandin E2 Induced Functional Expression of Early Growth Response Factor-1 by EP4, but Not EP2, Prostanoid Receptors via the Phosphatidylinositol 3-Kinase and Extracellular Signal-regulated Kinases

    Hiromichi Fujino;Wei Xu;John W. Regan

  • Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.

    Jon W. Lomasney;Wulfing Lorenz;Lee F. Allen;Klim King

  • Effector coupling mechanisms of the cloned 5-HT1A receptor.

    Annick Fargin;John R. Raymond;John W. Regan;Susanna Cotecchia

  • Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells.

    S Cotecchia;B K Kobilka;K W Daniel;R D Nolan

  • Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase *

    Rennolds S. Ostrom;Caroline Gregorian;Ryan M. Drenan;Yang Kevin Xiang

  • Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase.

    James J. Onorato;Krzysztof Palczewski;John W. Regan;Marc G. Caron

  • Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles.

    R A Cerione;J W Regan;H Nakata;J Codina

  • Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

    Hiromichi Fujino;Sambhitab Salvi;John W. Regan

  • Cloned human aquaporin-1 is a cyclic GMP-gated ion channel.

    Todd L. Anthony;Heddwen L. Brooks;Daniela Boassa;Sergey Leonov

  • Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

    J. L. Benovic;J. W. Regan;H. Matsui;F. Mayor

  • Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

    L. Tong;C. Pargellis;L. Churchill;P. Cirillo

  • Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic

    Masayuki Wada;Cynthia J. DeLong;Yu H. Hong;Caroline J. Rieke

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Marc G. Caron
Marc G. Caron Duke University
Henry I. Yamamura
Henry I. Yamamura University of Arizona
Brian K. Kobilka
Brian K. Kobilka Stanford University
Susanna Cotecchia
Susanna Cotecchia University of Lausanne
Patricia B. Hoyer
Patricia B. Hoyer University of Arizona
John R. Raymond
John R. Raymond Medical College of Wisconsin
Marilyn Halonen
Marilyn Halonen University of Arizona
Bo R. Rueda
Bo R. Rueda Massachusetts General Hospital
Alvin H. Schmaier
Alvin H. Schmaier University Hospitals of Cleveland

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing John W. Regan

Trending Scientists

Recently Published Articles