World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
117
Citations
45288
World Ranking
727
National Ranking
462

Medicine

D-Index
117
Citations
45236
World Ranking
4232
National Ranking
2316

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Paul A. Insel is affiliated with the University of California, San Diego in the United States. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology, focusing extensively on receptor mechanisms and signaling, infectious diseases, and immunology.

The scientist's work covers several main fields of study, including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields within their research include:

  • Molecular Biology
  • Infectious Diseases
  • Psychiatry and Mental health
  • Immunology
  • Pharmacology

Paul A. Insel has authored numerous publications, prominently appearing in the following venues:

  • British Journal of Pharmacology
  • The Annual Review of Pharmacology and Toxicology
  • The FASEB Journal
  • Pharmacological Reviews
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers include:

  • "ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020" (2020, British Journal of Pharmacology)
  • "Planning experiments: Updated guidance on experimental design and analysis and their reporting III" (2022, British Journal of Pharmacology)
  • "A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research" (2020, British Journal of Pharmacology)
  • "A hypothesis for pathobiology and treatment of COVID-19: The centrality of ACE1/ACE2 imbalance" (2020, British Journal of Pharmacology)
  • "Risks of ACE Inhibitor and ARB Usage in COVID-19: Evaluating the Evidence" (2020, Clinical Pharmacology & Therapeutics)

Their research topics also reflect current medical challenges and methodology, highlighting:

  • Receptor Mechanisms and Signaling
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Cancer, Stress, Anesthesia, and Immune Response
  • Long-Term Effects of COVID-19
  • Mast cells and histamine
  • Computational Drug Discovery Methods

Frequent collaborators include:

  • Krishna Sriram
  • Cristina Salmerón
  • Amrita Ahluwalia
  • Giuseppe Cirino
  • Gary J. Stephens

Paul A. Insel has received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2005 and is a member of the Association of American Physicians.

Best Publications

  • Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

    Michael J Curtis;Steve Alexander;Giuseppe Cirino;James R Docherty

  • G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

    Krishna Sriram;Paul A. Insel

  • Experimental design and analysis and their reporting: new guidance for publication in BJP.

    Michael J Curtis;Richard A Bond;Domenico Spina;Amrita Ahluwalia

  • Protein kinase C isozymes and the regulation of diverse cell responses

    Edward C. Dempsey;Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields

  • ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020.

    Elliott Lilley;S. Clare Stanford;David E. Kendall;Stephen P.H. Alexander

  • ATP Release Guides Neutrophil Chemotaxis via P2Y2 and A3 Receptors

    Yu Chen;Ross Corriden;Yoshiaki Inoue;Linda Yip

  • A Single Amino Acid Mutation Contributes to Adaptive Beach Mouse Color Pattern

    Hopi E. Hoekstra;Rachel J. Hirschmann;Richard A. Bundey;Paul A. Insel

  • REGULATION AND INHIBITION OF PHOSPHOLIPASE A2

    Jesús Balsinde;María A. Balboa;Paul A. Insel;Edward A. Dennis

  • Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology.

    Steve P H Alexander;Richard E Roberts;Brad R S Broughton;Christopher G Sobey

  • A Model of the Kinetics of Insulin in Man

    Robert S. Sherwin;Karl J. Kramer;Jordan D. Tobin;Paul A. Insel

  • Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling.

    Brian P. Head;Hemal H. Patel;Paul A. Insel

  • Adrenergic Receptors in Man

    Harvey J. Motulsky;Paul A. Insel

  • Caveolae as Organizers of Pharmacologically Relevant Signal Transduction Molecules

    Hemal H. Patel;Fiona Murray;Paul A. Insel

  • The evolving role of lipid rafts and caveolae in G protein‐coupled receptor signaling: implications for molecular pharmacology

    Rennolds S Ostrom;Paul A Insel

  • Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation

    Ross Corriden;Paul A. Insel

  • Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

    Vladimir Vacic;Vladimir Vacic;Shane McCarthy;Dheeraj Malhotra;Dheeraj Malhotra;Fiona Murray

  • Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

    Linda Yip;Tobias Woehrle;Ross Corriden;Mark Hirsh

  • Are there multiple imidazoline binding sites

    Martin C. Michel;Paul A. Insel

  • Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

    Tobias Woehrle;Linda Yip;Abdallah Elkhal;Yuka Sumi

  • EB2000 symposium report Protein kinase C isozymes and the regulation of diverse cell responses

    Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields

Frequent Co-Authors

Hemal H. Patel
Hemal H. Patel University of California, San Diego
David M. Roth
David M. Roth University of California San Diego
Daniel T. O'Connor
Daniel T. O'Connor University of California, San Diego
Volker Vallon
Volker Vallon University of California, San Diego
Wolfgang G. Junger
Wolfgang G. Junger Beth Israel Deaconess Medical Center
Alan S. Maisel
Alan S. Maisel University of California, San Diego
Henry R. Bourne
Henry R. Bourne University of California, San Francisco
Michael G. Ziegler
Michael G. Ziegler University of California, San Diego
Andrew M. Lowy
Andrew M. Lowy University of California, San Diego
Philip Coffino
Philip Coffino Rockefeller University

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