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Biology and Biochemistry

D-Index
60
Citations
16632
World Ranking
11776
National Ranking
5065

Overview

Wolfgang G. Junger is affiliated with Beth Israel Deaconess Medical Center in the United States. Their research is primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on several subfields including Physiology, Endocrine and Autonomic Systems, Immunology, Neurology, and Surgery.

Their work covers a variety of topics, notably:

  • Adenosine and Purinergic Signaling
  • Neuroscience of respiration and sleep
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neonatal Respiratory Health Research
  • Fatty Acid Research and Health
  • Sleep and related disorders
  • Neuroscience and Neuropharmacology Research

Junger's publication record includes appearances in venues such as Purinergic Signalling, Journal of Allergy and Clinical Immunology, Brain Behavior and Immunity, Nature, and Science Immunology.

Selected recent papers illustrate the focus and scope of their research:

  • "Negative feedback control of neuronal activity by microglia," 2020, Nature
  • "Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2," 2020, Science Immunology
  • "The purinergic receptor P2Y11 choreographs the polarization, mitochondrial metabolism, and migration of T lymphocytes," 2020, Science Signaling
  • "Mitochondria Synergize With P2 Receptors to Regulate Human T Cell Function," 2020, Frontiers in Immunology
  • "Optimized HPLC method to elucidate the complex purinergic signaling dynamics that regulate ATP, ADP, AMP, and adenosine levels in human blood," 2022, Purinergic Signalling

Frequent co-authors include Carola Ledderose, with whom Junger has collaborated on 19 publications, Simon C. Robson with 5 joint papers, Eleftheria-Angeliki Valsami (4 joint publications), Larissa C. Engert (4 joint publications), and Careen Biniamin (4 joint publications).

Best Publications

  • Circulating mitochondrial DAMPs cause inflammatory responses to injury

    Qin Zhang;Mustafa Raoof;Yu Chen;Yuka Sumi

  • Immune cell regulation by autocrine purinergic signalling

    Wolfgang G. Junger

  • ATP Release Guides Neutrophil Chemotaxis via P2Y2 and A3 Receptors

    Yu Chen;Ross Corriden;Yoshiaki Inoue;Linda Yip

  • Negative feedback control of neuronal activity by microglia

    Ana Badimon;Hayley J. Strasburger;Pinar Ayata;Xinhong Chen

  • CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

    Prakash K. Gupta;Prakash K. Gupta;Jernej Godec;Jernej Godec;David Wolski;Emily Adland

  • Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

    Linda Yip;Tobias Woehrle;Ross Corriden;Mark Hirsh

  • Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

    Tobias Woehrle;Linda Yip;Abdallah Elkhal;Yuka Sumi

  • Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock.

    Niren Angle;David B. Hoyt;Raul Coimbra;Forrest Liu

  • Hypertonic Saline Resuscitation Decreases Susceptibility to Sepsis after Hemorrhagic Shock

    Raul Coimbra;David B. Hoyt;Wolfgang G. Junger;Niren Angle

  • HYPERTONIC SALINE RESUSCITATION: A TOOL TO MODULATE IMMUNE FUNCTION IN TRAUMA PATIENTS?

    Wolfgang G. Junger;Raul Coimbra;Forrest C. Liu;Crystal Herdon-Remelius

  • Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption

    Timo Rieg;Richard A. Bundey;Yu Chen;George Deschenes

  • Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38.

    W G Junger;D B Hoyt;R E Davis;C Herdon-Remelius

  • Purinergic signaling: a fundamental mechanism in neutrophil activation.

    Yu Chen;Yongli Yao;Yuka Sumi;Andrew Li

  • Measurement of oxidative burst in neutrophils.

    Yu Chen;Wolfgang G. Junger

  • Abandon the mouse research ship? Not just yet!

    Marcin F. Osuchowski;Daniel G. Remick;James A. Lederer;Charles H. Lang

  • Hypertonic saline resuscitation reduces neutrophil margination by suppressing neutrophil L selectin expression.

    Niren Angle;David B. Hoyt;Ruy Cabello-Passini;Crystal Herdon-Remelius

  • Leptin acts as a mitogenic and antiapoptotic factor for colonic cancer cells.

    M R Hoda;S J Keely;L S Bertelsen;W G Junger

  • Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation.

    Anna M. Weihs;Christiane Fuchs;Andreas H. Teuschl;Joachim Hartinger

  • Hypertonic Saline Resuscitation Restores Hemorrhage-Induced Immunosuppression by Decreasing Prostaglandin E2and Interleukin-4 Production☆

    Raul Coimbra;Wolfgang G. Junger;David B. Hoyt;Forrest C. Liu

  • Mitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signaling.

    Yi Bao;Carola Ledderose;Thomas Seier;Amelie F. Graf;Amelie F. Graf

Frequent Co-Authors

David B. Hoyt
David B. Hoyt American College of Surgeons
Simon C. Robson
Simon C. Robson Beth Israel Deaconess Medical Center
Yu Chen
Yu Chen Memorial Sloan Kettering Cancer Center
Yu Chen
Yu Chen New York University
Paul A. Insel
Paul A. Insel University of California, San Diego
Raul Coimbra
Raul Coimbra Riverside University Health System - Medical Center
Heinz Redl
Heinz Redl Ludwig Boltzmann Institute for Experimental and Clinical Traumatology
William F. Loomis
William F. Loomis University of California, San Diego
W. Nicholas Haining
W. Nicholas Haining Arsenal Biosciences (United States)
Arlene H. Sharpe
Arlene H. Sharpe Harvard University

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