World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
47265
World Ranking
833
National Ranking
56

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2013 - Member of Academia Europaea

Overview

Martin J. Lohse is affiliated with the ISAR Bioscience Institute in Germany. Their research spans several interconnected fields within biochemistry, genetics, molecular biology, medicine, and neuroscience. Over their career, they have produced a substantial body of work focusing primarily on receptor mechanisms and signaling.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Within these broader disciplines, Lohse's work delves into specific subfields such as:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Infectious Diseases
  • Radiology, Nuclear Medicine and Imaging
  • Oncology

Their research topics cover a range of molecular and cellular biology questions, including:

  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Monoclonal and Polyclonal Antibodies Research
  • Phosphodiesterase Function and Regulation
  • Advanced Fluorescence Microscopy Techniques
  • Photoreceptor and Optogenetics Research
  • Mass Spectrometry Techniques and Applications

Lohse's publication record includes works published in multiple scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Cell
  • Molecular Pharmacology
  • Methods in Molecular Biology

Recent selected papers include:

  • "Optical Mapping of cAMP Signaling at the Nanometer Scale" (2020, Cell)
  • "Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling" (2022, Cell)
  • "Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors" (2020, Nature Chemical Biology)
  • "Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists" (2020, Proceedings of the National Academy of Sciences)
  • "Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes" (2021, Proceedings of the National Academy of Sciences)

Frequent co-authors collaborating with Lohse include:

  • Paolo Annibale
  • Ali Işbilir
  • Andreas Böck
  • Ulrike Zabel
  • Isabella Maiellaro

Martin J. Lohse was recognized as a Member of Academia Europaea in 2013, reflecting their involvement and standing within the broader scientific community.

Best Publications

  • Beta-arrestin: a protein that regulates beta-adrenergic receptor function

    Martin J. Lohse;Jeffrey L. Benovic;Juan Codina;Marc G. Caron

  • Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

    M Ungerer;M Böhm;J S Elce;E Erdmann

  • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

    Stefan Engelhardt;Lutz Hein;Frank Wiesmann;Martin J. Lohse

  • What Is the Role of β-Adrenergic Signaling in Heart Failure?

    Martin J. Lohse;Stefan Engelhardt;Thomas Eschenhagen

  • The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT 1A receptor

    Annick Fargin;John R. Raymond;Martin J. Lohse;Brian K. Kobilka

  • Novel single chain cAMP sensors for receptor-induced signal propagation.

    Viacheslav O. Nikolaev;Moritz Bünemann;Lutz Hein;Annette Hannawacker

  • Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells

    K N Klotz;J Hessling;J Hegler;Christer Owman

  • β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

    Viacheslav O. Nikolaev;Viacheslav O. Nikolaev;Alexey Moshkov;Alexander R. Lyon;Michele Miragoli

  • Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.

    Davide Calebiro;Viacheslav O. Nikolaev;Maria Cristina Gagliani;Tiziana de Filippis

  • Molecular mechanisms of membrane receptor desensitization

    Martin J. Lohse

  • A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells.

    Carsten Hoffmann;Guido Gaietta;Moritz Bünemann;Stephen R Adams

  • G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

    Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola

  • Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

    Moritz Bünemann;Monika Frank;Martin J. Lohse

  • Fluorescence Resonance Energy Transfer–Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases

    Marco Mongillo;Theresa McSorley;Sandrine Evellin;Arvind Sood

  • Neural cell adhesion molecules influence second messenger systems

    Ulrich Schuch;Martin J. Lohse;Melitta Schachner

  • Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.

    M J Lohse;J L Benovic;M G Caron;R J Lefkowitz

  • Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.

    Jean-Pierre Vilardaga;Moritz Bünemann;Cornelius Krasel;Mariàn Castro

  • Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization.

    S Pippig;S Andexinger;M J Lohse

  • 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors.

    Martin J. Lohse;Karl-Norbert Klotz;Jutta Lindenborn-Fotinos;Martin Reddington

  • Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2.

    Kristina Lorenz;Martin J. Lohse;Ursula Quitterer

Frequent Co-Authors

Viacheslav O. Nikolaev
Viacheslav O. Nikolaev Universität Hamburg
Karl-Norbert Klotz
Karl-Norbert Klotz University of Würzburg
Jean-Pierre Vilardaga
Jean-Pierre Vilardaga University of Pittsburgh
Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Marc G. Caron
Marc G. Caron Duke University
Georg Ertl
Georg Ertl University of Würzburg
Michel Bouvier
Michel Bouvier University of Montreal
Graeme Milligan
Graeme Milligan University of Glasgow
Jean-Philippe Pin
Jean-Philippe Pin University of Montpellier
Sauro Vittori
Sauro Vittori University of Camerino

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students of Biology and Biochemistry have a variety of flexible online degree and career pathways to consider in the healthcare field. One popular option is health information management, which allows graduates to work with patient data, electronic records, and healthcare analytics. Many health information management schools online now offer affordable programs with strong career placement rates.

Medical coding and billing are also in-demand careers that do not require years of clinical training. Those interested in salary potential can reference current trends in medical coding jobs salary. The medical coding job outlook remains strong, with many positions available in hospitals, clinics, and remote work environments.

For students who want to apply their biology background to wellness and science-based nutrition careers, consider earning an online nutrition masters. These programs can prepare you for roles in dietetics, health education, and research—expanding your options beyond the laboratory.

Best Scientists Citing Martin J. Lohse

Trending Scientists

Recently Published Articles