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D-Index & Metrics

Chemistry

D-Index
77
Citations
16781
World Ranking
4138
National Ranking
1306

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Phillip Crews is affiliated with the University of California, Santa Cruz in the United States. Their research work spans multiple domains within biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular biology and pharmacology as primary subfields.

Their scholarly contributions include notable publications across various scientific journals. Recent papers authored or coauthored by Crews include:

  • Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates, 2020, The Journal of Antibiotics
  • Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2, 2021, Bioorganic & Medicinal Chemistry
  • An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications, 2020, PLoS ONE
  • Assessing the ethnobotanical potential of Carissa opaca berries by merging outcomes from metabolomics profiling, enzyme assays, and in silico docking studies, 2021, Food Chemistry
  • Suppression of MAPK/NF-kB and activation of Nrf2 signaling by Ajugarin-I in EAE model of multiple sclerosis, 2023, Phytotherapy Research

Frequent coauthors collaborating with Crews include:

  • Erin P. McCauley
  • Tyler A. Johnson
  • Joseph D. Morris
  • David Coppage
  • Kashif Bashir

Their research is frequently featured in several scientific journals, notably:

  • Journal of Natural Products
  • ACS Omega
  • The Journal of Antibiotics
  • Bioorganic & Medicinal Chemistry
  • PLoS ONE

Phillip Crews' main fields of study are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study emphasize:

  • Molecular Biology
  • Pharmacology
  • Organic Chemistry
  • Plant Science
  • Biotechnology

Key topics within their body of work include:

  • Microbial Natural Products and Biosynthesis
  • Chemical Synthesis and Analysis
  • Marine Sponges and Natural Products
  • Bioactive Compounds and Antitumor Agents
  • Genomics, phytochemicals, and oxidative stress
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis

Phillip Crews received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

    Maina Lepourcelet;Ying-Nan P. Chen;Huisheng Wang

  • Organic Structure Analysis

    Phillip Crews;Jaime Rodríguez;Marcel Jaspars

  • Jasplakinolide, a cyclodepsipeptide from the marine sponge, Jaspis SP.

    Phillip Crews;Lawrence V Manes;Mark Boehler

  • Psammaplins from the Sponge Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase

    Ivette C Piña;Jeffrey T Gautschi;Gui-Yang-Sheng Wang;Miranda L Sanders

  • Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

    Katja M Fisch;Cristian Gurgui;Nina Heycke;Sonia A van der Sar

  • Psymberin, A Potent Sponge-Derived Cytotoxin from Psammocinia Distantly Related to the Pederin Family

    Robert H. Cichewicz;Frederick A. Valeriote;Phillip Crews

  • Fijianolides, polyketide heterocycles from a marine sponge

    Emilio Quinoa;Yao Kakou;Phillip Crews

  • Jasplakinolide's Inhibition of the Growth of Prostate Carcinoma Cells In Vitro With Disruption of the Actin Cytoskeleton

    Adrian M. J. Senderowicz;Gurmeet Kaur;Eduardo Sainz;Charmaine Laing

  • New and known diketopiperazines from the Caribbean sponge, Calyx cf. podatypa.

    Madeline Adamczeski;Andrea R. Reed;Phillip Crews

  • Novel sponge-derived amino acids. 5. Structures, stereochemistry, and synthesis of several new heterocycles

    Madeline Adamczeski;Emilio Quinoa;Phillip Crews

  • Comparison of fascaplysin and related alkaloids: a study of structures, cytotoxicities, and sources.

    Nathaniel L Segraves;Sarah J Robinson;Daniel Garcia;Sadri A Said

  • The antifouling activity of natural and synthetic phenol acid sulphate esters

    James S. Todd;Richard C. Zimmerman;Phillip Crews;Randall S. Alberte

  • Jasplakinolide induces apoptosis in various transformed cell lines by a caspase-3-like protease-dependent pathway.

    Chikako Odaka;Miranda L. Sanders;Phillip Crews

  • Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products

    Christopher L Ahlbach;Katrina W Lexa;Andrew T Bockus;Valerie Chen

  • Synthesis and study of pseudoaromatic compounds. X. A reevaluation of the question of aromatic character in tropone, tropolone, and substituted heptafulvenes based on the analysis of the nuclear magnetic resonance spectra of these and several related compounds

    Domenick J. Bertelli;Thomas G. Andrews;Phillip O. Crews

  • Highlights of marine invertebrate-derived biosynthetic products: Their biomedical potential and possible production by microbial associants

    Ocky K. Radjasa;Yvette M. Vaske;Gabriel Navarro;Hélène C. Vervoort

  • Enzyme inhibitors: new and known polybrominated phenols and diphenyl ethers from four Indo-Pacific Dysidea sponges.

    Xiong Fu;Francis J. Schmitz;Meledath Govindan;Sayed A. Abbas

  • Phenolic constituents of Psammaplysilla

    Emilio Quiñoà;Phillip Crews

  • Azonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola.

    Quan Xiang Wu;Mitchell S. Crews;Marija Draskovic;Johann Sohn

  • Mycothiazole, a polyketide heterocycle from a marine sponge

    Phillip. Crews;Yao. Kakou;Emilio. Quinoa

Frequent Co-Authors

Emilio Quiñoá
Emilio Quiñoá University of Santiago de Compostela
Jon Clardy
Jon Clardy Harvard University
Emil B. Lobkovsky
Emil B. Lobkovsky Cornell University
Marcel Jaspars
Marcel Jaspars University of Aberdeen
Theodore R. Holman
Theodore R. Holman University of California, Santa Cruz
James H. McKerrow
James H. McKerrow University of California, San Diego
Francis J. Schmitz
Francis J. Schmitz University of Oklahoma
William H. Gerwick
William H. Gerwick University of California, San Diego
Leonard F. Bjeldanes
Leonard F. Bjeldanes University of California, Berkeley
Matthias Platzer
Matthias Platzer Leibniz Association

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