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Theodore R. Holman

D-Index & Metrics

Chemistry

D-Index
45
Citations
6889
World Ranking
16508
National Ranking
4104

Theodore R. Holman publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Theodore R. Holman sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 129 publications — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Theodore R. Holman D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Theodore R. Holman sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 45 D-Index — 10th percentile

10% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Theodore R. Holman is affiliated with the University of California, Santa Cruz in the United States. Their research primarily focuses on biochemical and molecular biology aspects related to lipoxygenase enzymes, eicosanoids, and their implications in health and disease.

Their work spans the fields of biochemistry, genetics, molecular biology, and medicine, with notable contributions in subfields including biochemistry, molecular biology, nutrition and dietetics, pharmacology, and cardiology and cardiovascular medicine.

The main topics covered in Holman's research are:

  • Eicosanoids and Hypertension Pharmacology
  • Fatty Acid Research and Health
  • Inflammatory mediators and NSAID effects
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism

Recent papers authored or co-authored by Holman include:

  • Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis (2020, Redox Biology)
  • 15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5 (2020, Journal of Lipid Research)
  • Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death (2024, Angewandte Chemie International Edition)
  • Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators (2020, Biochemistry)
  • DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway (2020, Journal of Thrombosis and Haemostasis)

Frequent collaborators in Holman's research include:

  • Michael Holinstat
  • Adriana Yamaguchi
  • Chakrapani Kalyanaraman
  • Matthew P. Jacobson
  • Steve Perry

Holman's publications are commonly found in several scientific venues. Most frequent publication venues include:

  • Biochemistry
  • Blood
  • Archives of Biochemistry and Biophysics
  • Journal of Clinical and Translational Science
  • Journal of Lipid Research

Best Publications

  • PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

    Sally E. Wenzel;Yulia Y. Tyurina;Jinming Zhao;Claudette M. St. Croix

  • N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice.

    Saravanan S. Karuppagounder;Lauren Alin;Yingxin Chen;David Brand

  • Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.

    Joshua D. Deschamps;Victor A. Kenyon;Theodore R. Holman

  • Purification and characterization of VanR and the cytosolic domain of VanS: a two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147.

    Gerard D. Wright;Theodore R. Holman;Christopher T. Walsh

  • Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.

    Diana R. Tomchick;Phuc Phan;Marcin Cymborowski;Wladek Minor

  • Structure−Activity Relationship Studies of Nordihydroguaiaretic Acid Inhibitors toward Soybean, 12-Human, and 15-Human Lipoxygenase

    Stephanie Whitman;Mikail Gezginci;Barbara N Timmermann;Theodore R Holman

  • A Re(V)-catalyzed C-N bond-forming route to human lipoxygenase inhibitors.

    Rachana V Ohri;Alexander T Radosevich;K James Hrovat;Christine Musich

  • Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium

    Theodore R. Holman;Zhen Wu;Barry L. Wanner;Christopher T. Walsh

  • Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

    Taro Amagata;Stephanie Whitman;Tyler A. Johnson;Chad C. Stessman

  • Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis.

    Tamil S. Anthonymuthu;Yulia Y. Tyurina;Wan-Yang Sun;Karolina Mikulska-Ruminska

  • Reactions of NO with Mn(II) and Mn(III) centers coordinated to carboxamido nitrogen: synthesis of a manganese nitrosyl with photolabile NO.

    Kaushik Ghosh;Aura A Eroy-Reveles;Belem Avila;Theodore R Holman

  • Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.

    Yesseny Vasquez-Martinez;Rachana V. Ohri;Victor Kenyon;Theodore R. Holman

  • Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors.

    Jennifer Carroll;Erika N. Jonsson;Rainer Ebel;Michael S. Hartman

  • Models for diferrous forms of iron-oxo proteins. Structure and properties of [Fe2BPMP(O2CR)2]BPh4 complexes

    A. S. Borovik;M. P. Hendrich;T. R. Holman;E. Munck

  • Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.

    Ganesha Rai;Netra Joshi;Joo Eun Jung;Yu Liu

  • Synthesis and Structure–Activity Relationship Studies of 4-((2-Hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase

    Diane K. Luci;J. Brian Jameson;Adam Yasgar;Giovanni Diaz

  • Novel human lipoxygenase inhibitors discovered using virtual screening with homology models.

    Victor Kenyon;Ilya Chorny;Wendy J. Carvajal;Theodore R. Holman

  • Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation

    Kenneth N. Ikei;Jennifer Yeung;Patrick L. Apopa;Jesús Ceja

  • Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.

    Jennifer Yeung;Benjamin E. Tourdot;Pilar Fernandez-Perez;Joanne Vesci

  • Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

    Robert H. Cichewicz;Victor A. Kenyon;Stephanie Whitman;Nancy M. Morales

  • Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis.

    Robert H. Cichewicz;Laura J. Clifford;Peter R. Lassen;Xiaolin Cao

  • Discovery of Platelet-Type 12-Human Lipoxygenase Selective Inhibitors by High-Throughput Screening of Structurally Diverse Libraries

    Joshua D. Deschamps;Jeffrey T. Gautschi;Stephanie Whitman;Tyler A. Johnson

Frequent Co-Authors

Ajit Jadhav
Ajit Jadhav Pfizer (Germany)
Anton Simeonov
Anton Simeonov National Institutes of Health
Matthew P. Jacobson
Matthew P. Jacobson University of California, San Francisco
Phillip Crews
Phillip Crews University of California, Santa Cruz
Jerry L. Nadler
Jerry L. Nadler New York Medical College
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Hülya Bayır
Hülya Bayır University of Pittsburgh
Wilfred A. van der Donk
Wilfred A. van der Donk University of Illinois at Urbana-Champaign
Rajiv R. Ratan
Rajiv R. Ratan Cornell University
Eng H. Lo
Eng H. Lo Harvard University

External Links

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