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Chemistry

D-Index
73
Citations
13782
World Ranking
5136
National Ranking
1592

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1993 - Fellow of Alfred P. Sloan Foundation

Overview

Pradip K. Mascharak is affiliated with the University of California, Santa Cruz in the United States. Their research spans the fields of Materials Science, Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on subfields including Materials Chemistry, Molecular Biology, Biomedical Engineering, Oncology, and Pediatrics, Perinatology and Child Health.

Their scholarly work covers various scientific topics such as Heme Oxygenase-1 and Carbon Monoxide, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Nanoplatforms for cancer theranostics, Neonatal Health and Biochemistry, Cancer, Hypoxia, and Metabolism, and Pharmacogenetics and Drug Metabolism.

Among the recent publications bearing their influence are:

  • Light-assisted and remote delivery of carbon monoxide to malignant cells and tissues: Photochemotherapy in the spotlight, 2020, Journal of Photochemistry and Photobiology C Photochemistry Reviews
  • Carbon Monoxide Inhibits Cytochrome P450 Enzymes CYP3A4/2C8 in Human Breast Cancer Cells, Increasing Sensitivity to Paclitaxel, 2021, Journal of Medicinal Chemistry
  • Gold Drugs with {Au(PPh3)}+ Moiety: Advantages and Medicinal Applications, 2020, ChemMedChem
  • Reaction of Carbon Monoxide with Cystathionine β-Synthase: Implications on Drug Efficacies in Cancer Chemotherapy, 2020, Future Medicinal Chemistry
  • Nitric oxide delivery platforms derived from a photoactivatable Mn(II) nitrosyl complex: Entry to photopharmacology, 2022, Journal of Inorganic Biochemistry

Frequent co-authors of Mascharak include Jenny Stenger-Smith, Indranil Chakraborty, Ramatoulaye Ouattara, Mireille Kamariza, and Carolyn R. Bertozzi. Their collaborative work has contributed to research across several notable publication venues.

They have multiple publications in these venues:

  • The Cambridge Structural Database (5 publications)
  • Journal of Photochemistry and Photobiology C Photochemistry Reviews (1 publication)
  • Journal of Medicinal Chemistry (1 publication)
  • ChemMedChem (1 publication)
  • Future Medicinal Chemistry (1 publication)

Throughout their career, Mascharak has received recognition including election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008 and as a Fellow of the Alfred P. Sloan Foundation in 1993.

Best Publications

  • X-ray spectroscopic studies of nickel complexes, with application to the structure of nickel sites in hydrogenases

    G. J. Colpas;M. J. Maroney;C. Bagyinka;M. Kumar

  • Photoactive Ruthenium Nitrosyls: Effects of Light and Potential Application as NO Donors.

    Michael J. Rose;Pradip K. Mascharak

  • Photoactive ruthenium nitrosyls as NO donors: how to sensitize them toward visible light.

    Nicole L. Fry;Pradip K. Mascharak

  • Structural and functional models of nitrile hydratase

    Pradip K Mascharak

  • Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets

    Indranil Chakraborty;Samantha J. Carrington;Pradip K. Mascharak

  • Sensitization of ruthenium nitrosyls to visible light via direct coordination of the dye resorufin: trackable NO donors for light-triggered NO delivery to cellular targets.

    Michael J Rose;Nicole L Fry;Rebecca Marlow;Lindsay Hinck

  • [Fe(PMA)]n+ (n = 1,2): good models of iron-bleomycins and examples of mononuclear non-heme iron complexes with significant oxygen-activation capabilities

    Richard J. Guajardo;Samuel E. Hudson;Steven J. Brown;Pradip K. Mascharak

  • Fe(III) and Co(III) centers with carboxamido nitrogen and modified sulfur coordination: lessons learned from nitrile hydratase.

    Todd C. Harrop;Pradip K. Mascharak

  • Near-infrared light activated release of nitric oxide from designed photoactive manganese nitrosyls: strategy, design, and potential as NO donors.

    Aura A. Eroy-Reveles;Yvonne Leung;Christine M. Beavers;Marilyn M. Olmstead

  • Nickel L-Edge Soft X-ray Spectroscopy of Nickel−Iron Hydrogenases and Model CompoundsEvidence for High-Spin Nickel(II) in the Active Enzyme

    Hongxin Wang;C. Y. Ralston;D. S. Patil;R. M. Jones

  • A Synthetic Analogue of the Active Site of Fe-Containing Nitrile Hydratase with Carboxamido N and Thiolato S as Donors: Synthesis, Structure, and Reactivities

    Juan C. Noveron;Marilyn M. Olmstead;Pradip K. Mascharak

  • Fiat Lux: selective delivery of high flux of nitric oxide (NO) to biological targets using photoactive metal nitrosyls.

    Michael J Rose;Pradip K Mascharak

  • Coordination of carboxamido nitrogen to tervalent iron:insight into a new chapter of iron chemistry

    Dana S. Marlin;Pradip K. Mascharak

  • Co(III)-alkylperoxo complexes: syntheses, structure-reactivity correlations, and use in the oxidation of hydrocarbons.

    Ferman A. Chavez;Pradip K. Mascharak

  • Photoactive metal carbonyl complexes as potential agents for targeted CO delivery.

    Margarita A. Gonzales;Pradip K. Mascharak

  • Syntheses, structures, and properties of new manganese carbonyls as photoactive CO-releasing molecules: design strategies that lead to CO photolability in the visible region.

    Margarita A. Gonzalez;Samantha J. Carrington;Nicole L. Fry;Jose L. Martinez

  • Photolabile Ruthenium Nitrosyls with Planar Dicarboxamide Tetradentate N4 Ligands: Effects of In-Plane and Axial Ligand Strength on NO Release

    Apurba K. Patra;Michael J. Rose;Karen A. Murphy;Marilyn M. Olmstead

  • Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules

    Margarita A. Gonzalez;Melanie A. Yim;Stephanie Cheng;Amie Moyes

  • The First Non‐Heme Iron(III) Complex with a Ligated Carboxamido Group That Exhibits Photolability of a Bound NO Ligand

    Apurba K. Patra;Raman Afshar;Marilyn M. Olmstead;Pradip K. Mascharak

  • Toward Functional Models of the Nickel Sites in [FeNi] and [FeNiSe] Hydrogenases: Syntheses, Structures, and Reactivities of Nickel(II) Complexes Containing [NiN3S2] and [NiN3Se2] Chromophores

    Christine A. Marganian;Haresh Vazir;Narayan Baidya;Marilyn M. Olmstead

Frequent Co-Authors

Marilyn M. Olmstead
Marilyn M. Olmstead University of California, Davis
Indranil Chakraborty
Indranil Chakraborty Purdue University West Lafayette
Douglas W. Stephan
Douglas W. Stephan University of Toronto
Animesh Chakravorty
Animesh Chakravorty Indian Association for the Cultivation of Science
Edward I. Solomon
Edward I. Solomon Stanford University
Keith O. Hodgson
Keith O. Hodgson Stanford University
Britt Hedman
Britt Hedman SLAC National Accelerator Laboratory
Stephen P. Cramer
Stephen P. Cramer Search for Extraterrestrial Intelligence
Michael W. W. Adams
Michael W. W. Adams University of Georgia

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