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D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
33043
World Ranking
4002
National Ranking
1976

Overview

Christopher A. Bradfield is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily focuses on the broad field of Biochemistry, Genetics and Molecular Biology, with 26 publications contributing to this area.

Their work spans several subfields, including Molecular Biology, Immunology, Cancer Research, Physiology, and Endocrine and Autonomic Systems. Notably, Molecular Biology represents the largest share with 17 publications. Their research topics reflect a concentration in Gene Regulatory Network Analysis, Cancer, Hypoxia, and Metabolism, Circadian rhythm and melatonin, Immune cells in cancer, Dietary Effects on Health, Genetics, Aging, and Longevity in Model Organisms, as well as Mass Spectrometry Techniques and Applications.

Christopher A. Bradfield has contributed to multiple scientific journals and publication venues. Frequent venues for their work include bioRxiv (Cold Spring Harbor Laboratory) with four publications, Chemical Research in Toxicology and Toxicology Reports with two publications each, along with contributions to the Journal of Clinical Investigation and Environment International.

Their recent papers illustrate the range and interdisciplinary nature of their research:

  • The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model (2020, Chemical Research in Toxicology)
  • Circadian disruption, clock genes, and metabolic health (2024, Journal of Clinical Investigation)
  • Diverse mechanisms by which chemical pollutant exposure alters gut microbiota metabolism and inflammation (2024, Environment International)
  • The circadian clock is disrupted in pancreatic cancer (2023, PLoS Genetics)
  • The aryl hydrocarbon receptor as a model PAS sensor (2021, Toxicology Reports)

Collaborations figure largely in their scientific output. Frequent coauthors include Sean M. Ronnekleiv-Kelly, Manabu Nukaya, Patrick R. Carney, Patrick B. Schwartz, and Mark E. Berres, indicating ongoing partnerships with researchers contributing to related fields.

Best Publications

  • Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals

    Maureen K. Bunger;Lisa D. Wilsbacher;Susan M. Moran;Cynthia Clendenin

  • Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

    Biliana Marcheva;Kathryn Moynihan Ramsey;Ethan D. Buhr;Yumiko Kobayashi

  • An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

    Joshua D. Mezrich;John H. Fechner;Xiaoji Zhang;Brian P. Johnson

  • AH RECEPTOR SIGNALING PATHWAYS

    Jennifer V. Schmidt;Christopher A. Bradfield

  • The PAS Superfamily: Sensors of Environmental and Developmental Signals

    Yi-Zhong Gu;John B. Hogenesch;Christopher A. Bradfield

  • Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.

    Kristine M. Burbach;Alan Poland;Christopher A. Bradfield

  • Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

    J. V. Schmidt;G. H.-T. Su;J. K. Reddy;M. C. Simon

  • THE BASIC-HELIX-LOOP-HELIX-PAS ORPHAN MOP3 FORMS TRANSCRIPTIONALLY ACTIVE COMPLEXES WITH CIRCADIAN AND HYPOXIA FACTORS

    John B. Hogenesch;Yi-Zhong Gu;Sanjay Jain;Christopher A. Bradfield

  • Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT

    Emin Maltepe;Jennifer V. Schmidt;David Baunoch;Christopher A. Bradfield

  • The search for endogenous activators of the aryl hydrocarbon receptor.

    Linh P. Nguyen;Christopher A. Bradfield

  • AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

    Jacob S Lee;Marina Cella;Keely G McDonald;Cecilia Garlanda

  • Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha.

    Gu Yz;Moran Sm;Hogenesch Jb;Wartman L

  • Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

    Leonard F. Bjeldanes;Jin-Young Kim;Karl R. Grose;James C. Bartholomew

  • Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway

    John B. Hogenesch;John B. Hogenesch;William K. Chan;Victoria H. Jackiw;R. Clark Brown

  • Ligand-dependent Interaction of the Aryl Hydrocarbon Receptor With a Novel Immunophilin Homolog in Vivo

    Lucy A. Carver;Christopher A. Bradfield

  • The AH-receptor: Genetics, Structure and Function

    Hollie I. Swanson;Christopher A. Bradfield

  • The aryl hydrocarbon receptor: a perspective on potential roles in the immune system.

    Emily A. Stevens;Joshua D. Mezrich;Christopher A. Bradfield

  • DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins

    Hollie I. Swanson;William K. Chan;Christopher A. Bradfield

  • Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

    Garet P. Lahvis;Susanne L. Lindell;Russell S. Thomas;Robert S. McCuskey

  • Obesity in mice with adipocyte-specific deletion of clock component Arntl

    Georgios K Paschos;Salam Ibrahim;Wen-Liang Song;Takeshige Kunieda

Frequent Co-Authors

E.W.N. Glover
E.W.N. Glover Durham University
John B. Hogenesch
John B. Hogenesch Cincinnati Children's Hospital Medical Center
Mark Craven
Mark Craven University of Wisconsin–Madison
Joseph S. Takahashi
Joseph S. Takahashi The University of Texas Southwestern Medical Center
Janardan K. Reddy
Janardan K. Reddy Northwestern University
Garret A. FitzGerald
Garret A. FitzGerald University of Pennsylvania
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Leonard F. Bjeldanes
Leonard F. Bjeldanes University of California, Berkeley
James J. Schauer
James J. Schauer University of Wisconsin–Madison
M. Celeste Simon
M. Celeste Simon University of Pennsylvania

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