D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 12,192 119 World Ranking 9334 National Ranking 320

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His main research concerns Receptor, Aryl hydrocarbon receptor, Internal medicine, Biochemistry and Cytosol. His work deals with themes such as Exon, Stereochemistry, Binding site and Cell biology, which intersect with Receptor. His studies deal with areas such as Xenobiotic and CYP1B1 as well as Aryl hydrocarbon receptor.

His study focuses on the intersection of Internal medicine and fields such as Endocrinology with connections in the field of Hydroxylation, 3,3'-Diindolylmethane and Microsome. His research in Biochemistry is mostly concerned with Enzyme inducer. The concepts of his Cytosol study are interwoven with issues in Inducer, Methylcholanthrene and Molecular biology.

His most cited work include:

  • Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer (946 citations)
  • Enzyme induction in the cytochrome P-450 system. (574 citations)
  • Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation. (356 citations)

What are the main themes of his work throughout his whole career to date?

Allan B. Okey mainly investigates Receptor, Internal medicine, Biochemistry, Cytosol and Aryl hydrocarbon receptor. His Receptor research is multidisciplinary, relying on both Cell culture, Nuclear receptor, Stereochemistry and Mechanism of action. His Internal medicine study combines topics from a wide range of disciplines, such as Endocrinology and Downregulation and upregulation.

His studies in Cytosol integrate themes in fields like Benzopyrene, Molecular mass, Tetrachlorodibenzo-p-dioxin, Receptor complex and Steroid. His research integrates issues of Molecular biology, Transcriptome, Toxicity and CYP1B1 in his study of Aryl hydrocarbon receptor. In his work, Cell biology is strongly intertwined with Xenobiotic, which is a subfield of Toxicity.

He most often published in these fields:

  • Receptor (48.85%)
  • Internal medicine (32.06%)
  • Biochemistry (29.01%)

What were the highlights of his more recent work (between 2008-2019)?

  • Aryl hydrocarbon receptor (29.01%)
  • Transcriptome (15.27%)
  • Toxicity (23.66%)

In recent papers he was focusing on the following fields of study:

Allan B. Okey mostly deals with Aryl hydrocarbon receptor, Transcriptome, Toxicity, Gene and Molecular biology. His work carried out in the field of Aryl hydrocarbon receptor brings together such families of science as Receptor, Xenobiotic and CYP1B1. His Toxicity research includes themes of Cytochrome b5, type A, Microarray and Endocrinology.

His study in the field of Messenger RNA is also linked to topics like Chemokine receptor and Glutamate dehydrogenase 1. His Messenger RNA study results in a more complete grasp of Biochemistry. His Molecular biology study incorporates themes from Monooxygenase and Cycloheximide.

Between 2008 and 2019, his most popular works were:

  • Systematic evaluation of medium-throughput mRNA abundance platforms. (61 citations)
  • Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities (49 citations)
  • Hepatic transcriptomic responses to TCDD in dioxin-sensitive and dioxin-resistant rats during the onset of toxicity. (41 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Aryl hydrocarbon receptor, Molecular biology, Transcriptome, Toxicity and Receptor. His studies link CYP1B1 with Aryl hydrocarbon receptor. His Molecular biology study integrates concerns from other disciplines, such as Aryl hydrocarbon receptor nuclear translocator, Messenger RNA and Methylcholanthrene.

To a larger extent, Allan B. Okey studies Biochemistry with the aim of understanding Messenger RNA. His Transcriptome research incorporates themes from Microarray and Transactivation. His work in Toxicity covers topics such as CYP1A2 which are related to areas like Xenobiotic, NFE2L2 and CYP2S1.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer

Daniel W. Nebert;Timothy P. Dalton;Allan B. Okey;Frank J. Gonzalez.
Journal of Biological Chemistry (2004)

1277 Citations

Enzyme induction in the cytochrome P-450 system.

Allan B. Okey.
Pharmacology & Therapeutics (1990)

865 Citations

The Ah receptor: Mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds

Allan B. Okey;David S. Riddick;Patricia A. Harper.
Toxicology Letters (1994)

486 Citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

A B Okey;G P Bondy;M E Mason;G F Kahl.
Journal of Biological Chemistry (1979)

457 Citations

Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries

Nathalie Tijet;Paul C Boutros;Ivy D Moffat;Allan B Okey.
Molecular Pharmacology (2006)

393 Citations

Genetic Mechanisms Controlling the Induction of Polysubstrate Monooxygenase (P-450) Activities

D. W. Nebert;H. J. Eisen;M. Negishi;M. A. Lang.
Annual Review of Pharmacology and Toxicology (1981)

374 Citations

Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptor

S. Bandiera;S. Safe;A.B. Okey.
Chemico-Biological Interactions (1982)

298 Citations

Molecular biology of the aromatic hydrocarbon (dioxin) receptor

Allan B. Okey;David S. Riddick;Patricia A. Harper.
Trends in Pharmacological Sciences (1994)

292 Citations

Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation

Jellinck Ph;Forkert Pg;Riddick Ds;Okey Ab.
Biochemical Pharmacology (1993)

286 Citations

An Aryl Hydrocarbon Receptor Odyssey to the Shores of Toxicology: The Deichmann Lecture, International Congress of Toxicology-XI

Allan B. Okey.
Toxicological Sciences (2007)

282 Citations

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