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Luis A. Videla

Luis A. Videla

D-Index & Metrics

Medicine

D-Index
74
Citations
15992
World Ranking
19500
National Ranking
5

Overview

Luis A. Videla is affiliated with the University of Chile in Chile and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans critical areas such as liver disease diagnosis and treatment, diet, metabolism, fatty acid health, and lipid metabolism.

The researcher's publication record includes key recent papers focusing on liver and metabolic health. Notable articles include:

  • "Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration" (2020) published in Digestive and Liver Disease
  • "Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver disease" (2022) published in Prostaglandins Leukotrienes and Essential Fatty Acids
  • "Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View" (2020) published in Nutrients
  • "Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency" (2023) published in BioFactors
  • "Perspectives in liver redox imbalance: Toxicological and pharmacological aspects underlying iron overloading, nonalcoholic fatty liver disease, and thyroid hormone action" (2021) published in BioFactors

Videla frequently collaborates with several co-authors, including Rodrigo Valenzuela, Andrea del Campo, Jessica Zúñiga-Hernández, and Alejandra Espinosa. These collaborations have contributed to a substantial body of work in related fields.

Their research outputs have been published across multiple venues, with the highest number in the journals Nutrients (4 publications), Current Medicinal Chemistry (3 publications), International Journal of Molecular Sciences (3 publications), Food & Function (3 publications), and Prostaglandins Leukotrienes and Essential Fatty Acids (2 publications).

In terms of fields of study, Luis A. Videla's primary contributions lie within Medicine, accounting for 49 publications, followed by Biochemistry, Genetics and Molecular Biology with 22 papers. Subfields of study indicate a focus on epidemiology with 19 publications, endocrinology, diabetes and metabolism with 11, nutrition and dietetics also with 11, and physiology and biochemistry with 9 publications each.

The main research topics covered include:

  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Fatty Acid Research and Health
  • Lipid metabolism and biosynthesis
  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Liver Disease and Transplantation

Best Publications

  • Increase in long-chain polyunsaturated fatty acid n − 6/n − 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease

    Julia Araya;Ramón Rodrigo;Luis A. Videla;Lilian Thielemann

  • Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients

    Luis A. Videla;Ramón Rodrigo;Myriam Orellana;Virginia Fernandez

  • Up-Regulation of PPAR-γ mRNA Expression in the Liver of Obese Patients: an Additional Reinforcing Lipogenic Mechanism to SREBP-1c Induction

    Paulina Pettinelli;Luis A. Videla

  • Experimental alcohol-induced hepatic necrosis: suppression by propylthiouracil.

    Y Israel;H Kalant;H Orrego;J M Khanna

  • Alcohol ingestion, liver glutathione and lipoperoxidation: Metabolic interrelations and pathological implications

    Luis A. Videla;Alfonso Valenzuela

  • Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease.

    Luis A. Videla;Ramón Rodrigo;Julia Araya;Jaime Poniachik

  • Enhancement in liver SREBP-1c/PPAR-α ratio and steatosis in obese patients: Correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion

    Paulina Pettinelli;Talía del Pozo;Julia Araya;Ramón Rodrigo

  • Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: Relation to lipid peroxidation

    Virginia Fernandez;Ximena Barrientos;Katina Kipreos;Alfonso Valenzuela

  • Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity.

    L. Videla;J. Bernstein;Y. Israel

  • Factors that modify the metabolism of ethanol in rat liver and adaptive changes produced by its chronic administration

    L. Videla;Y. Israel

  • Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging

    Francisca Echeverría;Macarena Ortiz;Rodrigo Valenzuela;Luis A. Videla

  • N-3 PUFA Supplementation Triggers PPAR-α Activation and PPAR-α/NF-κB Interaction: Anti-Inflammatory Implications in Liver Ischemia-Reperfusion Injury

    Jessica Zúñiga;Milena Cancino;Fernando Medina;Patricia Varela

  • Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications.

    Israel Y;Videla L;Bernstein J

  • Insulin resistance and oxidative stress interdependency in non-alcoholic fatty liver disease

    Luis A. Videla;Ramón Rodrigo;Julia Araya;Jaime Poniachik

  • Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell.

    J. Bernstein;L. Videla;Y. Israel

  • Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat.

    Alfonso Valenzuela;Cristina Lagos;Karen Schmidt;Luis A. Videla

  • The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity.

    Rodrigo Valenzuela;Luis A. Videla

  • Oxidative stress-mediated hepatotoxicity of iron and copper: role of Kupffer cells.

    Luis A Videla;Virginia Fernández;Gladys Tapia;Patricia Varela

  • Antioxidant Properties of the Flavonoids Silybin and (+)-Cyanidanol-3: Comparison with Butylated Hydroxyanisole and Butylated Hydroxytoluene

    A. Valenzuela;R. Guerra;L. A. Videla

  • Oxidative stress signaling underlying liver disease and hepatoprotective mechanisms.

    Luis A Videla

Frequent Co-Authors

Eduardo Lissi
Eduardo Lissi University of Santiago Chile
Yedy Israel
Yedy Israel University of Chile
Susana Puntarulo
Susana Puntarulo University of Buenos Aires
Alberto Boveris
Alberto Boveris University of Buenos Aires
Cesar G. Fraga
Cesar G. Fraga University of California, Davis
Susana Llesuy
Susana Llesuy University of Buenos Aires
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
Cecilia R Giulivi
Cecilia R Giulivi University of California, Davis
Mario Comporti
Mario Comporti University of Siena
Nibaldo C. Inestrosa
Nibaldo C. Inestrosa Pontificia Universidad Católica de Chile

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