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Lisbeth A. Guethlein

Lisbeth A. Guethlein

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
12567
World Ranking
16018
National Ranking
6648

Overview

Lisbeth A. Guethlein is affiliated with Stanford University in the United States. Their research spans several areas within immunology, molecular biology, and related biomedical sciences, as reflected in their extensive publication record and collaborations.

Guethlein's recent scholarly output includes notable papers published in recognized scientific journals. These include:

  • KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation, 2020, Blood Advances
  • Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets, 2022, Nature Computational Science
  • Insulin-Responsive Transcription Factors, 2021, Biomolecules
  • Adaptive Admixture of HLA Class I Allotypes Enhanced Genetically Determined Strength of Natural Killer Cells in East Asians, 2021, Molecular Biology and Evolution
  • Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures, 2023, HLA

Guethlein frequently collaborates with certain researchers, indicating long-term scientific partnerships. Frequent co-authors include:

  • Peter Parham
  • Paul J. Norman
  • Alexander Dilthey
  • Nicholas R. Pollock
  • Neda Nemat-Gorgani

Their work has appeared most often in several specific venues, which are prominent within the fields of immunology and molecular biology. These venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • HLA
  • Frontiers in Immunology
  • Nature Communications

Guethlein's primary fields of study comprise immunology and microbiology, along with biochemistry, genetics, and molecular biology. Within these broader fields, their research subfields include:

  • Immunology
  • Molecular Biology
  • Cancer Research
  • Hematology
  • Plant Science

The scientist's main research topics focus on immune system functioning and related molecular mechanisms. Their areas of emphasis cover:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Reproductive System and Pregnancy
  • Single-cell and spatial transcriptomics
  • RNA Research and Splicing
  • Cancer-related molecular mechanisms research

Best Publications

  • Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002

    Steven G. E. Marsh;Peter Parham;Bo Dupont;Daniel E. Geraghty

  • Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

    Sarah Cooley;Daniel J. Weisdorf;Lisbeth A. Guethlein;John P. Klein

  • The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

    Laurent Abi-Rached;Matthew J. Jobin;Matthew J. Jobin;Subhash Kulkarni;Alasdair McWhinnie

  • Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry

    Amir Horowitz;Dara M. Strauss-Albee;Michael Leipold;Jessica Kubo

  • Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

    Sarah A Cooley;Elizabeth Trachtenberg;Tracy L. Bergemann;Koy Saeteurn

  • Allelic Polymorphism Synergizes with Variable Gene Content to Individualize Human KIR Genotype

    Heather G. Shilling;Lisbeth A. Guethlein;Nathalie W. Cheng;Clair M. Gardiner

  • Different NK Cell Surface Phenotypes Defined by the DX9 Antibody Are Due to KIR3DL1 Gene Polymorphism

    Clair M. Gardiner;Lisbeth A. Guethlein;Heather G. Shilling;Marcelo Pando

  • The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

    Cemalettin Bekpen;Julia P Hunn;Christoph Rohde;Iana Parvanova

  • Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT

    Jeffery S. Miller;Sarah Cooley;Peter Parham;Sherif S. Farag

  • Two families of GTPases dominate the complex cellular response to IFN-gamma.

    Ulrich Boehm;Lisbeth Guethlein;Thorsten Klamp;Kural Ozbek

  • A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

    Sarah Cooley;Feng Xiao;Michelle Pitt;Michelle Gleason

  • Genetic control of human NK cell repertoire

    Heather G Shilling;Neil Thomas Young;Lisbeth A Guethlein;Nathalie W Cheng

  • Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression.

    Makoto Yawata;Nobuyo Yawata;Karina L. McQueen;Nathalie W. Cheng

  • KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.

    Thorsten Graef;Achim K. Moesta;Paul J. Norman;Laurent Abi-Rached

  • Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

    Chul Woo Pyo;Lisbeth A. Guethlein;Quyen Vu;Ruihan Wang

  • Human-specific Evolution of Killer Cell Immunoglobulin-Like Receptor Recognition of Major Histocompatibility Complex Class I Molecules

    Peter Parham;Paul J. Norman;Laurent Abi-Rached;Lisbeth A. Guethlein

  • Class I HLA haplotypes form two schools that educate NK cells in different ways

    Amir Horowitz;Zakia Djaoud;Neda Nemat-Gorgani;Jeroen Blokhuis

  • IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex

    Giuseppe Maccari;Giuseppe Maccari;James Robinson;Keith Ballingall;Lisbeth A. Guethlein

  • Donor-recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell transplantation.

    Karina L. McQueen;Kristel M. Dorighi;Lisbeth A. Guethlein;Ruby Wong

  • Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia

    Sarah A Cooley;Daniel J Weisdorf;Lisbeth A. Guethlein;John P. Klein

Frequent Co-Authors

Peter Parham
Peter Parham Stanford University
Steven G.E. Marsh
Steven G.E. Marsh University College London
Jeffrey S. Miller
Jeffrey S. Miller University of Minnesota
Ronald E. Bontrop
Ronald E. Bontrop Utrecht University
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
Beatrice H. Hahn
Beatrice H. Hahn University of Pennsylvania
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Raja Rajalingam
Raja Rajalingam University of California, San Francisco
Mostafa Ronaghi
Mostafa Ronaghi Dynamics Special Purpose Corp.
Stephen R. Spellman
Stephen R. Spellman Medical College of Wisconsin

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