World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
67
Citations
18471
World Ranking
2653
National Ranking
233

Genetics

D-Index
67
Citations
18118
World Ranking
2520
National Ranking
321

Overview

Derek Middleton is affiliated with the University of Liverpool in the United Kingdom. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on subfields including Immunology, Molecular Biology, Hematology, Infectious Diseases, and Transplantation.

The main scientific topics covered in Middleton's work include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Vaccines and Immunoinformatics Approaches
  • Hematopoietic Stem Cell Transplantation
  • Renal Transplantation Outcomes and Treatments
  • Immune Responses and Vaccinations
  • SARS-CoV-2 and COVID-19 Research

Middleton has published extensively in several academic venues. Frequent publication venues include:

  • International Journal of Immunogenetics
  • Human Immunology
  • Frontiers in Immunology
  • Communications Biology
  • Methods in Molecular Biology

Recent papers authored or co-authored by Middleton include:

  • "Predictive immunogenetic markers in COVID-19" (2021) published in Human Immunology
  • "A Proteome-Wide Immunoinformatics Tool to Accelerate T-Cell Epitope Discovery and Vaccine Design in the Context of Emerging Infectious Diseases: An Ethnicity-Oriented Approach" (2021) published in Frontiers in Immunology
  • "A snapshot of human leukocyte antigen (HLA) diversity using data from the Allele Frequency Net Database" (2020) published in Human Immunology
  • "High resolution allele genotyping and haplotype frequencies for NGS based HLA 11 loci of 5266 Hong Kong Chinese bone marrow donors" (2020) published in Human Immunology
  • "High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation" (2021) published in Communications Biology

Middleton collaborates frequently with several co-authors, notably:

  • Steven G. E. Marsh
  • Australia Dyer
  • W. H. Howell
  • Tokyo Mack
  • Marcelo Fernández-Viña

Best Publications

  • Human NK Cell Education by Inhibitory Receptors for MHC Class I

    Nicolas Anfossi;Pascale André;Sophie Guia;Sophie Guia;Christine S Falk

  • Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002

    Steven G. E. Marsh;Peter Parham;Bo Dupont;Daniel E. Geraghty

  • Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

    Faviel F. Gonzalez-Galarza;Stephen E. Christmas;Derek Middleton;Andrew R Jones

  • Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.

    Faviel F. Gonzalez-Galarza;Louise Y. C. Takeshita;Eduardo José Melo dos Santos;Felicity Kempson

  • Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools.

    Faviel F. Gonzalez-Galarza;Antony McCabe;Eduardo José Melo dos Santos;James Jones

  • The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

    Laurent Abi-Rached;Matthew J. Jobin;Matthew J. Jobin;Subhash Kulkarni;Alasdair McWhinnie

  • Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments

    Omar M.A El-Agnaf;Ross Jakes;Martin D Curran;Derek Middleton;Derek Middleton

  • New allele frequency database: www.allelefrequencies.net

    D. Middleton;L. Menchaca;H. Rood;R. Komerofsky

  • The extensive polymorphism of KIR genes

    Derek Middleton;Faviel Gonzelez

  • Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002: Marsh et al : KIR nomenclature report, 2002

    S.G.E. Marsh;P. Parham;B. Dupont;D.E. Geraghty

  • A DNA-RFLP typing system that positively identifies serologically well-defined and ill-defined HLA-DR and DQ alleles, including DRw10

    Jeffrey L. Bidwell;Elizabeth A. Bidwell;David A. Savage;Derek Middleton

  • Common and well-documented HLA alleles: 2012 update to the CWD catalogue.

    Steven J. Mack;Pedro Cano;Jill A. Hollenbach;Jun He

  • Natural killer cells and their receptors.

    Derek Middleton;Martin Curran;Martin Curran;Lynne Maxwell;Lynne Maxwell

  • Survival of DNA HLA-DR typed and matched cadaver kidney transplants

    G. Opelz;J. Mytilineos;S. Scherer;H. Dunckley

  • Association between polymorphism in regulatory region of gene encoding tumour necrosis factor α and risk of Alzheimer's disease and vascular dementia: a case-control study

    Shauna M McCusker;Martin D Curran;Kevin B Dynan;Catriona D McCullagh

  • Frequency of cytokine polymorphisms in populations from western Europe, Africa, Asia, the Middle East and South America.

    Ashley Meenagh;Fionnuala Williams;Owen A Ross;Chris Patterson

  • Genetic polymorphism of IL-12 p40 gene in immune-mediated disease

    M A Hall;E McGlinn;G Coakley;S A Fisher

  • Mitochondrial DNA polymorphism: its role in longevity of the Irish population.

    Owen A Ross;Owen A Ross;Rose McCormack;Rose McCormack;Martin D Curran;Martin D Curran;R Alistair Duguid

  • Functional Polymorphism of the KIR3DL1/S1 Receptor on Human NK Cells

    Geraldine M. O’Connor;Kieran J. Guinan;Rodat T. Cunningham;Derek Middleton

  • Determination of HLA-A, -C, -B, -DRB1 allele and haplotype frequency in Japanese population based on family study

    N. Ikeda;H. Kojima;M. Nishikawa;K. Hayashi

  • Peptide antagonism as a mechanism for NK cell activation.

    Lena Fadda;Gwenoline Borhis;Parvin Ahmed;Kuldeep Cheent

Frequent Co-Authors

Gottfried Fischer
Gottfried Fischer Medical University of Vienna
Peter Parham
Peter Parham Stanford University
Christopher Patterson
Christopher Patterson Queen's University Belfast
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Steven G.E. Marsh
Steven G.E. Marsh University College London
Pierre-Antoine Gourraud
Pierre-Antoine Gourraud University of Nantes
Owen A. Ross
Owen A. Ross Mayo Clinic
Marcelo Fernandez-Vina
Marcelo Fernandez-Vina Stanford University
Carolyn Katovich Hurley
Carolyn Katovich Hurley Georgetown University
Machteld Oudshoorn
Machteld Oudshoorn Leiden University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in Genetics, there are several related online degrees and career pathways to consider. Many foundational courses, such as biology or medical administration, can be completed through flexible online programs. For instance, those drawn to healthcare data might explore the best accredited medical billing and coding schools online for programs that blend science with administrative skills.

For students aiming to accelerate their studies, fast degree programs allow you to graduate and enter the workforce more quickly. Many schools now offer self-directed learning, and choosing one of the self paced online colleges lets you tailor coursework to your schedule—ideal for balancing work or family commitments.

If application costs are a concern, look into the colleges with free application fees to make the admissions process more affordable. These flexible pathways open doors to varied careers in genetics, healthcare, and beyond, whether you want to work behind the scenes in data or pursue direct scientific research.

Best Scientists Citing Derek Middleton

Trending Scientists

Recently Published Articles