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Immunology

D-Index
44
Citations
7117
World Ranking
4793
National Ranking
2149

Overview

Raja Rajalingam is affiliated with the University of California, San Francisco in the United States. Their research spans mainly the fields of Medicine and Immunology and Microbiology, with significant contributions in subfields such as Immunology, Hematology, Transplantation, Molecular Biology, and Surgery.

The scientist's work addresses a range of topics including:

  • Renal Transplantation Outcomes and Treatments
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Hemophilia Treatment and Research
  • Hematopoietic Stem Cell Transplantation
  • Transplantation: Methods and Outcomes
  • Platelet Disorders and Treatments

Recent publications by Raja Rajalingam include the following papers:

  • "Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses," 2023, Cell Reports
  • "Hematopoietic Stem Cell Factors: Their Functional Role in Self-Renewal and Clinical Aspects," 2022, Frontiers in Cell and Developmental Biology
  • "Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression," 2023, Nature Biotechnology
  • "Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19," 2022, Frontiers in Genetics
  • "KIR-HLA gene diversities and susceptibility to lung cancer," 2022, Scientific Reports

Rajalingam frequently publishes in several scientific venues, including:

  • American Journal of Transplantation
  • Human Immunology
  • Frontiers in Genetics
  • Blood
  • Scientific Reports

Collaborations are a significant aspect of their research efforts. Frequent co-authors include:

  • Bernadette W. Luu
  • John Blangero
  • Tom E. Howard
  • Denice Kong
  • Marcio Almeida

This profile reflects a comprehensive research trajectory involving immune system functions, transplantation biology, and hematopoietic studies, combined with both clinical and molecular perspectives across multiple specialized domains.

Best Publications

  • The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

    Laurent Abi-Rached;Matthew J. Jobin;Matthew J. Jobin;Subhash Kulkarni;Alasdair McWhinnie

  • Different NK Cell Surface Phenotypes Defined by the DX9 Antibody Are Due to KIR3DL1 Gene Polymorphism

    Clair M. Gardiner;Lisbeth A. Guethlein;Heather G. Shilling;Marcelo Pando

  • Rapid Evolution of NK Cell Receptor Systems Demonstrated by Comparison of Chimpanzees and Humans

    Salim I Khakoo;Raja Rajalingam;Benny P Shum;Kristin Weidenbach

  • Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: guidelines from the NMDP/CIBMTR

    Jason Dehn;Stephen Spellman;Carolyn K. Hurley;Bronwen E. Shaw

  • Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression.

    Makoto Yawata;Nobuyo Yawata;Karina L. McQueen;Nathalie W. Cheng

  • Distinctive KIR and HLA diversity in a panel of north Indian Hindus

    Raja Rajalingam;Peter Krausa;Heather G. Shilling;Jason B. Stein

  • Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.

    Zinal S. Chheda;Gary Kohanbash;Gary Kohanbash;Kaori Okada;Naznin Jahan

  • Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans

    Zeying Du;David W. Gjertson;Elaine F. Reed;Raja Rajalingam

  • Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing

    Paul J Norman;Jill A Hollenbach;Neda Nemat-Gorgani;Wesley M Marin

  • Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells.

    Yi-Ping Jin;Michael C Fishbein;Jonathan W Said;Peter T Jindra

  • Domain Shuffling Has Been the Main Mechanism Forming New Hominoid Killer Cell Ig-Like Receptors

    Raja Rajalingam;Peter Parham;Laurent Abi-Rached

  • KIR2DL5, a Novel Killer-Cell Receptor with a D0-D2 Configuration of Ig-Like Domains

    Carlos Vilches;Raja Rajalingam;Markus Uhrberg;Clair M. Gardiner

  • KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation.

    Jeanette E. Boudreau;Fabio Giglio;Ted A. Gooley;Philip A. Stevenson

  • Polymerase Chain Reaction-Based Sequence-Specific Oligonucleotide Hybridization Analysis of HLA Class II Antigens in Pulmonary Tuberculosis: Relevance to Chemotherapy and Disease Severity

    R. Rajalingam;N. K. Mehra;R. C. Jain;V. P. Myneedu

  • Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes

    Benny P. Shum;Laura R. Flodin;David G. Muir;Raja Rajalingam

  • Immunogenetics as a tool in anthropological studies.

    Alicia Sanchez-Mazas;Marcelo Fernandez-Viña;Derek Middleton;Jill A Hollenbach

  • Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes.

    Raja Rajalingam;Mei Hong;Erin J. Adams;Benny P. Shum

  • Human diversity of killer cell immunoglobulin-like receptors and disease

    Raja Rajalingam

  • Allele-Level Haplotype Frequencies and Pairwise Linkage Disequilibrium for 14 KIR Loci in 506 European-American Individuals

    Cynthia Vierra-Green;David Roe;Lihua Hou;Carolyn Katovich Hurley

  • Transporter associated with antigen-processing (TAP) genes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis.

    R. Rajalingam;D. P. Singal;N. K. Mehra

  • Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic human migrations.

    Raja Rajalingam;Zeying Du;Ashley Meenagh;Lihui Luo

Frequent Co-Authors

Elaine F. Reed
Elaine F. Reed University of California, Los Angeles
Narinder K. Mehra
Narinder K. Mehra All India Institute of Medical Sciences
Peter Parham
Peter Parham Stanford University
John P. Roberts
John P. Roberts University of California, San Francisco
John Blangero
John Blangero The University of Texas Rio Grande Valley
Lisbeth A. Guethlein
Lisbeth A. Guethlein Stanford University
Jeffrey A. Golden
Jeffrey A. Golden Brigham and Women's Hospital
Eugene Maraskovsky
Eugene Maraskovsky CSL (United Kingdom)
Jonathan Braun
Jonathan Braun Cedars-Sinai Medical Center
Stephen R. Spellman
Stephen R. Spellman Medical College of Wisconsin

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