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Immunology

D-Index
72
Citations
22372
World Ranking
2190
National Ranking
197

Overview

Ashley Moffett is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple areas within medicine, with particular emphasis on immunology and microbiology. The scientist's work primarily focuses on obstetrics and gynecology, reproductive medicine, pediatrics, perinatology, child health, and public health, environmental, and occupational health.

Their recent publications demonstrate engagement with complex topics related to human reproduction and pregnancy. Notable papers include:

  • Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro, 2021, published in Nature Genetics
  • Single-cell roadmap of human gonadal development, 2022, published in Nature
  • Investigation of human trophoblast invasion in vitro, 2020, published in Human Reproduction Update
  • Spatial multiomics map of trophoblast development in early pregnancy, 2023, published in Nature
  • Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women, 2020, published in Nature Communications

Key research topics addressed by Moffett include pregnancy and preeclampsia studies, reproductive system and pregnancy, birth, development and health, global maternal and child health, endometriosis research and treatment, immune cell function and interaction, and neonatal respiratory health research.

Frequent co-authors appearing in collaboration with Moffett are:

  • Margherita Y. Turco
  • Annettee Nakimuli
  • Lucy Gardner
  • Andrew Sharkey
  • Imelda Namagembe

Publication venues where Moffett's work regularly appears include the American Journal of Obstetrics and Gynecology, bioRxiv (Cold Spring Harbor Laboratory), AJOG Global Reports, Placenta, and Nature Communications. These venues reflect the clinical and biological emphasis of their research contributions.

Best Publications

  • Single-cell reconstruction of the early maternal–fetal interface in humans

    Roser Vento-Tormo;Roser Vento-Tormo;Mirjana Efremova;Rachel A. Botting;Margherita Y. Turco

  • Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success

    Susan E. Hiby;James J. Walker;Kevin M. O'Shaughnessy;Christopher W.G. Redman

  • Immunology of placentation in eutherian mammals.

    Ashley Moffett;Charlie Loke

  • Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium

    Margherita Y Turco;Lucy Gardner;Jasmine Hughes;Tereza Cindrova-Davies

  • Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro.

    Luz Garcia-Alonso;Louis-François Handfield;Kenny Roberts;Konstantina Nikolakopoulou;Konstantina Nikolakopoulou

  • Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution

    Peter Parham;Ashley Moffett

  • Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2

    Susan E. Hiby;Richard Apps;Andrew M. Sharkey;Lydia E. Farrell

  • Uterine NK cells: active regulators at the maternal-fetal interface

    Ashley Moffett;Francesco Colucci

  • BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

    Andreia S. Bernardo;Tiago Faial;Tiago Faial;Lucy Gardner;Kathy K. Niakan

  • Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies.

    Richard Apps;Shawn P. Murphy;Raymond Fernando;Lucy Gardner

  • Influence of HLA-C Expression Level on HIV Control

    Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen

  • Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage

    S.E. Hiby;L. Regan;W. Lo;L. Farrell

  • Human uterine leukocytes and pregnancy

    Unknown

  • Dendritic cells in the human decidua.

    Lucy Gardner;Ashley Moffett

  • HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

    Rasmi Thomas;Richard Apps;Ying Qi;Xiaojiang Gao

  • Investigation of human trophoblast invasion in vitro.

    Yassen Abbas;Margherita Y Turco;Graham J Burton;Ashley Moffett

  • What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

    Cheryl Q.E. Lee;Lucy Gardner;Margherita Turco;Nancy Zhao

  • Maternal uterine NK cell–activating receptor KIR2DS1 enhances placentation

    Shiqiu Xiong;Andrew M. Sharkey;Philippa R. Kennedy;Lucy Gardner

  • A critical look at HLA-G

    Richard Apps;Lucy Gardner;Ashley Moffett

  • A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1.

    Richard Apps;Lucy Gardner;Andrew M Sharkey;Nick Holmes

  • First do no harm: uterine natural killer (NK) cells in assisted reproduction

    Ashley Moffett;Norman Shreeve

  • Natural killer cells, miscarriage, and infertility.

    Ashley Moffett;Lesley Regan;Peter Braude

Frequent Co-Authors

Lucy Gardner
Lucy Gardner University of Cambridge
Francesco Colucci
Francesco Colucci University of Cambridge
Myriam Hemberger
Myriam Hemberger University of Calgary
Graham J. Burton
Graham J. Burton University of Cambridge
John Trowsdale
John Trowsdale University of Cambridge
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Peter Parham
Peter Parham Stanford University
Alison M. Elliott
Alison M. Elliott London School of Hygiene & Tropical Medicine
Per Magnus
Per Magnus Norwegian Institute of Public Health
Pontiano Kaleebu
Pontiano Kaleebu London School of Hygiene & Tropical Medicine

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