World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
58
Citations
11412
World Ranking
10668
National Ranking
60

Biology and Biochemistry

D-Index
60
Citations
12627
World Ranking
11973
National Ranking
85

Overview

Seppo Auriola is affiliated with the University of Eastern Finland in Finland. Their research spans multiple fields with a primary focus on Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist has concentrated work in several subfields including Molecular Biology, Physiology, Oncology, Public Health, Environmental and Occupational Health, and Biochemistry.

Key research topics covered by Seppo Auriola include:

  • Drug Transport and Resistance Mechanisms
  • Metabolomics and Mass Spectrometry Studies
  • Amino Acid Enzymes and Metabolism
  • Alzheimer's disease research and treatments
  • Diet and metabolism studies
  • Lipoproteins and Cardiovascular Health
  • Adipose Tissue and Metabolism

Their frequent coauthors consist of Marko Lehtonen, Kati Hanhineva, Merja R. Häkkinen, Elena Puris, and Anton Klåvus.

Publications by Seppo Auriola have appeared in several recurring venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pharmaceutics
  • Scientific Reports
  • Journal of Controlled Release
  • Metabolomics

Recent papers authored by or involving Seppo Auriola include:

  • L-Type amino acid transporter 1 as a target for drug delivery (2020, Pharmaceutical Research)
  • Biopharmaceutics of Topical Ophthalmic Suspensions: Importance of Viscosity and Particle Size in Ocular Absorption of Indomethacin (2021, Pharmaceutics)
  • L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells (2020, ACS Chemical Neuroscience)
  • Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition (2022, Scientific Reports)
  • Metabolomic, Lipidomic and Proteomic Characterisation of Lipopolysaccharide-induced Inflammation Mouse Model (2022, Neuroscience)

Best Publications

  • Molecular mechanisms of action of bisphosphonates.

    M.J Rogers;J.C Frith;J.C Frith;S.P Luckman;S.P Luckman;F.P Coxon;F.P Coxon

  • Liquid chromatography/atmospheric pressure ionization-mass spectrometry in drug metabolism studies.

    R. Kostiainen;T. Kotiaho;T. Kuuranne;S. Auriola

  • A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.

    Hannu Mönkkönen;Seppo Auriola;Petri Lehenkari;Maarit Kellinsalmi

  • The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: Evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis

    Julie C. Frith;Jukka Mönkkönen;Seppo Auriola;Hannu Mönkkönen

  • Characterization of Paracellular and Aqueous Penetration Routes in Cornea, Conjunctiva and Sclera

    K M Hämäläinen;K Kananen;S Auriola;K Kontturi

  • Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

    Vanessa D. de Mello;Jussi Paananen;Jaana Lindström;Maria A. Lankinen

  • Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

    J. E. Laine;S. Auriola;M. Pasanen;R. O. Juvonen

  • Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs.

    Helena L. Benford;Julie C. Frith;Seppo Auriola;Jukka Mönkkönen

  • Comparison of Tuber Proteomes of Potato Varieties, Landraces, and Genetically Modified Lines

    Satu J. Lehesranta;Howard V. Davies;Louise V.T. Shepherd;Naoise Nunan

  • High-performance liquid chromatography with electrospray ionization mass spectrometry and diode array ultraviolet detection in the identification of flavonol aglycones and glycosides in berries

    Sari Häkkinen;Seppo Auriola

  • Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium.

    H S El-Nezami;A Chrevatidis;S Auriola;S Salminen

  • Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

    Marjo Tuomainen;Jaana Lindström;Marko Lehtonen;Seppo Auriola

  • Pyrrolidine Dithiocarbamate Activates Akt and Improves Spatial Learning in APP/PS1 Mice without Affecting β-Amyloid Burden

    Tarja M. Malm;Henna Iivonen;Gundars Goldsteins;Velta Keksa-Goldsteine

  • Immobilization of protein-coated drug nanoparticles in nanofibrillar cellulose matrices--enhanced stability and release.

    Hanna Katriina Valo;Miia Kovalainen;Päivi Laaksonen;Merja Häkkinen

  • L-Type amino acid transporter 1 as a target for drug delivery

    Elena Puris;Mikko Gynther;Seppo Auriola;Kristiina M. Huttunen

  • Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease and aging brain.

    Minna A. Korolainen;Seppo Auriola;Tuula A. Nyman;Irina Alafuzoff

  • Drug adsorption to plastic containers and retention of drugs in cultured cells under in vitro conditions.

    Joni J Palmgrén;Jukka Mönkkönen;Timo Korjamo;Anssi Hassinen

  • Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro

    Jukka Mönkkönen;Markku Taskinen;Seppo O.K. Auriola;Arto Urtti

  • Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry

    Seppo Auriola;Julie Frith;Michael J Rogers;Antti Koivuniemi

  • Metabolic signature of extracellular vesicles depends on the cell culture conditions.

    Mari Palviainen;Heikki Saari;Olli Kärkkäinen;Jenna Pekkinen

  • Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach.

    Katja Kanninen;Gundars Goldsteins;Seppo Auriola;Irina Alafuzoff

  • PEPTIDE-OLIGONUCLEOTIDE PHOSPHOROTHIOATE CONJUGATES WITH MEMBRANE TRANSLOCATION AND NUCLEAR LOCALIZATION PROPERTIES

    Maxim Antopolsky;Elena Azhayeva;Unni Tengvall;Seppo Auriola

Frequent Co-Authors

Arto Urtti
Arto Urtti University of Eastern Finland
Matti Poutanen
Matti Poutanen University of Turku
Michael J. Rogers
Michael J. Rogers Garvan Institute of Medical Research
Jari Koistinaho
Jari Koistinaho University of Helsinki
Sirpa Kärenlampi
Sirpa Kärenlampi University of Eastern Finland
Risto Kostiainen
Risto Kostiainen University of Helsinki
Tomi Järvinen
Tomi Järvinen University of Eastern Finland
Kaisa Poutanen
Kaisa Poutanen VTT Technical Research Centre of Finland
Tero Aittokallio
Tero Aittokallio University of Helsinki
Hannu Mykkänen
Hannu Mykkänen University of Eastern Finland

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying chemistry in the USA opens doors to diverse fields, including forensic science, where chemical knowledge is crucial. For those interested in applying their chemistry skills to criminal investigations, exploring forensic autopsy technician roles can be a practical starting point. These positions require specialized training that blends chemistry with anatomy and legal procedures.

Many students pursue their passions through accessible programs like online colleges for forensic science, offering flexibility to gain expertise without relocating. These programs often cover analytical techniques and laboratory procedures essential for crime scene analysis and evidence testing.

For those aiming for advanced roles, forensic psychology graduate programs online combine psychology and forensic science, helping students understand criminal behavior, which complements scientific investigations.

Exploring various careers in forensics reveals opportunities ranging from crime lab analysts to legal consultants. By aligning chemistry studies with these career paths, students can contribute meaningfully to the justice system while enjoying dynamic and rewarding work.

Best Scientists Citing Seppo Auriola

Trending Scientists