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Matti Poutanen

Matti Poutanen

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
16217
World Ranking
5432
National Ranking
44

Overview

Matti Poutanen is affiliated with the University of Turku in Finland and specializes in medicine, with a significant focus on biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including molecular biology, reproductive medicine, endocrinology, diabetes and metabolism, pulmonary and respiratory medicine, and genetics.

The scientist's primary research topics cover prostate cancer treatment and research, hormonal and reproductive studies, estrogen and related hormone effects, reproductive system and pregnancy, hypothalamic control of reproductive hormones, endometriosis research and treatment, and ovarian function and disorders.

Among their recent publications are the following papers:

  • Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer, 2020, Nature Communications
  • A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions, 2020, Scientific Data
  • Glycovariant-based lateral flow immunoassay to detect ovarian cancer-associated serum CA125, 2020, Communications Biology
  • Erbb4 regulates the oocyte microenvironment during folliculogenesis, 2020, Human Molecular Genetics
  • The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation, 2021, EMBO Reports

Poutanen has frequently collaborated with other researchers, including Claes Ohlsson, Laura L. Elo, Leena Strauss, Manuel Tena-Sempere, and Henrik Ryberg.

The scientist's work has been published in various venues, with the most common publication venues being Zenodo (CERN European Organization for Nuclear Research), bioRxiv (Cold Spring Harbor Laboratory), Endocrinology, The FASEB Journal, and Nature Communications.

Best Publications

  • Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice.

    Fu-Ping Zhang;Matti Poutanen;Johannes Wilbertz;Ilpo Huhtaniemi

  • Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior

    Gloria K Mak;Emeka K Enwere;Emeka K Enwere;Christopher Gregg;Christopher Gregg;Tomi Pakarainen

  • Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

    Sofia Movérare-Skrtic;Petra Henning;Xianwen Liu;Kenichi Nagano

  • Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

    Minna M. Miettinen;Mika V. J. Mustonen;Matti H. Poutanen;Veli V. Isomaa

  • Aromatase and 17 beta-hydroxysteroid dehydrogenase type 1 in human breast carcinoma

    Hironobu Sasano;Andra R. Frost;Ryuta Saitoh;Nobuhiro Harada

  • Estrogen-specific 17 beta-hydroxysteroid oxidoreductase type 1 (E.C. 1.1.1.62) as a possible target for the action of phytoestrogens.

    S Mäkelä;M Poutanen;J Lehtimäki;M L Kostian

  • The Transcriptional Corepressor RIP140 Regulates Oxidative Metabolism in Skeletal Muscle

    Asha Seth;Jennifer H. Steel;Donna Nichol;Victoria Pocock

  • Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium

    Sarah Berndt;Sophie Perrier d'Hauterive;Silvia Blacher;Christel Péqueux

  • Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase.

    Xiangdong Li;Elina Nokkala;Wei Yan;Tomi Streng

  • Inhibition of 17beta-hydroxysteroid oxidoreductase by flavonoids in breast and prostate cancer cells

    S. Mäkelä;M. Poutanen;M. L. Kostian;N. Lehtimäki

  • Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex

    Jukka Kero;Matti Poutanen;Fu Ping Zhang;Nafis Rahman

  • The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis.

    Fu-Ping Zhang;Tomi Pakarainen;Matti Poutanen;Jorma Toppari

  • Immunological analysis of 17β-hydroxysteroid dehydrogenase in benign and malignant human breast tissue

    M. Poutanen;V. Isomaa;V.-P. Lehto;R. Vihko

  • Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin.

    Susana B Rulli;Aino Kuorelahti;Oznur Karaer;Lauri J Pelliniemi

  • Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice.

    Tomi Pakarainen;Fu-Ping Zhang;Fu-Ping Zhang;Sari Mäkelä;Matti Poutanen

  • Molecular Characterization of Postnatal Development of Testicular Steroidogenesis in Luteinizing Hormone Receptor Knockout Mice

    Fu-ping Zhang;Tomi Pakarainen;Fei Zhu;Matti Poutanen

  • Loss of Heterozygosity at 16q24.1–q24.2 Is Significantly Associated with Metastatic and Aggressive Behavior of Prostate Cancer

    Jussi P. Elo;Päivi Härkönen;Atte P. Kyllönen;Olavi Lukkarinen

  • Peroxisomal multifunctional enzyme of beta-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization.

    Y M Qin;M H Poutanen;H M Helander;A P Kvist

  • Mouse Cysteine-Rich Secretory Protein 4 (CRISP4): A Member of the Crisp Family Exclusively Expressed in the Epididymis in an Androgen-Dependent Manner

    Jenni Jalkanen;Ilpo Huhtaniemi;Matti Poutanen

  • Site-directed mutagenesis of the putative active site of human 17 beta-hydroxysteroid dehydrogenase type 1.

    T J Puranen;M H Poutanen;H E Peltoketo;P T Vihko

Frequent Co-Authors

Ilpo Huhtaniemi
Ilpo Huhtaniemi Imperial College London
Claes Ohlsson
Claes Ohlsson University of Gothenburg
Tero Aittokallio
Tero Aittokallio University of Helsinki
Jorma Toppari
Jorma Toppari University of Turku
Manuel Tena-Sempere
Manuel Tena-Sempere University of Córdoba
Pirkko Vihko
Pirkko Vihko University of Helsinki
Seppo Auriola
Seppo Auriola University of Eastern Finland
Pirkko Härkönen
Pirkko Härkönen University of Turku
Olli Carpén
Olli Carpén University of Helsinki
Kim Pettersson
Kim Pettersson University of Turku

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