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Mikko J. Lammi

Mikko J. Lammi

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8897
World Ranking
17216
National Ranking
272

Overview

Mikko J. Lammi is affiliated with Umeå University in Sweden. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to subfields including Molecular Biology, Rheumatology, Nutrition and Dietetics, Nephrology, and Cancer Research.

The scientist's work investigates several main topics, notably in Osteoarthritis Treatment and Mechanisms, Selenium in Biological Systems, Bone Metabolism and Diseases, Gout, Hyperuricemia, Uric Acid, Connective Tissue Growth Factor Research, Protease and Inhibitor Mechanisms, and Trace Elements in Health.

Frequent publication venues for their research include Frontiers in Genetics, Cell Death and Disease, International Journal of Molecular Sciences, Bioengineering, and Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature.

Among recent papers authored or co-authored by Mikko J. Lammi are:

  • Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis (2021, Cell Death and Disease)
  • Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration (2024, Annals of the Rheumatic Diseases)
  • Alterations in the gut microbiota and metabolite profiles of patients with Kashin-Beck disease, an endemic osteoarthritis in China (2021, Cell Death and Disease)
  • Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China (2022, Arthritis Research & Therapy)
  • Proteomic analysis of knee cartilage reveals potential signaling pathways in pathological mechanism of Kashin-Beck disease compared with osteoarthritis (2020, Scientific Reports)

Mikko J. Lammi collaborates frequently with several researchers, including Xiong Guo, Yujie Ning, Chengjuan Qu, Xi Wang, and Yanan Zhang. Collaborations with these coauthors have resulted in multiple joint publications.

Best Publications

  • Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants.

    Jyrki Parkkinen;Jorma Ikonen;Mikko Lammi;Jukka Laakkonen

  • Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro.

    Jyrki J. Parkkinen;Mikko J. Lammi;Heikki J. Helminen;Markku Tammi

  • Epidermal growth factor activates hyaluronan synthase 2 in epidermal keratinocytes and increases pericellular and intracellular hyaluronan.

    Juha-Pekka Pienimäki;Kirsi Rilla;Csaba Fülöp;Reijo K. Sironen

  • EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation.

    Sanna Pasonen-Seppänen;Susanna Karvinen;Kari Törrönen;Juha M.T. Hyttinen

  • Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation

    Kai Kaarniranta;Mika Elo;Reijo Sironen;Mikko Lammi

  • Recent advances in the research of an endemic osteochondropathy in China: Kashin-Beck disease

    Xiong Guo;Wei-Juan Ma;Feng Zhang;Feng-Lin Ren

  • Remobilization does not fully restore immobilization induced articular cartilage atrophy.

    Jussi Haapala;Jari P.a. Arokoski;Mika M. Hyttinen;Mikko Lammi

  • Speed of sound in normal and degenerated bovine articular cartilage.

    Juha Töyräs;Mikko S Laasanen;Simo Saarakkala;Mikko J Lammi

  • Influence of short-term hydrostatic pressure on organization of stress fibers in cultured chondrocytes.

    Jyrki J. Parkkinen;Mikko J. Lammi;Ritva Inkinen;Matti Jortikka

  • Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2a1 gene for Type II collagen.

    Janne Sahlman;Ritva Inkinen;Teemu Hirvonen;Mikko J. Lammi

  • Regular joint loading in youth assists in the establishment and strengthening of the collagen network of articular cartilage and contributes to the prevention of osteoarthrosis later in life: a hypothesis.

    Heikki J. Helminen;Mika M. Hyttinen;Mikko J. Lammi;Jari P. A. Arokoski

  • Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage

    Petro Julkunen;Terhi Harjula;Jarkko Iivarinen;Juho Marjanen

  • Stress–relaxation of human patellar articular cartilage in unconfined compression: Prediction of mechanical response by tissue composition and structure

    Petro Julkunen;Wouter Wilson;Jukka S. Jurvelin;Jarno Rieppo

  • Expression of reduced amounts of structurally altered aggrecan in articular cartilage chondrocytes exposed to high hydrostatic pressure.

    Mikko Lammi;Ritva Inkinen;Jyrki Parkkinen;Tomi Häkkinen

  • Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage

    Matti O Jortikka;Ritva I Inkinen;Markku I Tammi;Jyrki J Parkkinen

  • Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin‐Beck disease

    Chen Duan;Xiong Guo;Xiao-Dong Zhang;Han-Jie Yu

  • Relative increase of biglycan and decorin and altered chondroitin sulfate epitopes in the degenerating human intervertebral disc.

    Ritva I. Inkinen;Mikko J. Lammi;Sirpa Lehmonen;Kaija Puustjarvi

  • Densitometric assay of nanogram quantities of proteoglycans precipitated on nitrocellulose membrane with Safranin O.

    Mikko Lammi;Markku Tammi

  • Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis

    Wei-Zhou Wang;Xiong Guo;Chen Duan;Wei Juan Ma

  • Contrast agent enhanced pQCT of articular cartilage.

    Antti Kallioniemi;Jukka Jurvelin;Miika Nieminen;Mikko Lammi

Frequent Co-Authors

Markku Tammi
Markku Tammi University of Eastern Finland
Heikki J. Helminen
Heikki J. Helminen University of Eastern Finland
Jukka S. Jurvelin
Jukka S. Jurvelin University of Eastern Finland
Kai Kaarniranta
Kai Kaarniranta University of Eastern Finland
Juha Töyräs
Juha Töyräs University of Eastern Finland
Simo Saarakkala
Simo Saarakkala University of Oulu
Raija Tammi
Raija Tammi University of Eastern Finland
Rami K. Korhonen
Rami K. Korhonen University of Eastern Finland
Heikki Kröger
Heikki Kröger University of Eastern Finland

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