World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
25937
World Ranking
2142
National Ranking
12

Overview

Markku Tammi is affiliated with the University of Eastern Finland in Finland. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focused interest in Molecular Biology, Cell Biology, Surgery, Oncology, and Oceanography as subfields of study.

The scientist's work covers various main topics including Proteoglycans and glycosaminoglycans research, Fibroblast Growth Factor Research, Glycosylation and Glycoproteins Research, Esophageal Cancer Research and Treatment, Ion channel regulation and function, Wnt/β-catenin signaling in development and cancer, and Cancer Cells and Metastasis.

Markku Tammi has contributed to several recent publications, reflecting these research interests. Notable papers include:

  • Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer, 2021, Scientific Reports
  • Cellular hyaluronan is associated with a poor prognosis in renal cell carcinoma, 2020, Urologic Oncology Seminars and Original Investigations
  • Zooplankton in relation to cyanobacteria across a geographic gradient in Archipelago Sea, northern Baltic, 2024, Boreal Environment Research Journal Archive
  • The calcium-activated chloride channel-associated protein rCLCA2 is expressed throughout rat epidermis, facilitates apoptosis and is downmodulated by UVB, 2021, Histochemistry and Cell Biology

Markku Tammi has frequently collaborated with several researchers. Frequent coauthors include:

  • Raija Tammi
  • Sanna Pasonen-Seppänen
  • Kyösti Tahkola
  • Maarit Ahtiainen
  • Jukka-Pekka Mecklin

The scientist's research is frequently published in various venues, among which are:

  • Scientific Reports
  • Urologic Oncology Seminars and Original Investigations
  • Histochemistry and Cell Biology
  • Boreal Environment Research Journal Archive

Best Publications

  • Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival.

    Päivi Auvinen;Raija Tammi;Jyrki Parkkinen;Markku Tammi

  • Hyaluronan-cell interactions in cancer and vascular disease.

    Bryan P. Toole;Thomas N. Wight;Markku I. Tammi

  • HYALURONAN BINDING BY CELL SURFACE CD44

    Jayne Lesley;Vincent C. Hascall;Markku Tammi;Robert Hyman

  • Hyaluronan and homeostasis : a balancing act

    Markku I. Tammi;Anthony J. Day;Eva A. Turley

  • Tumor Cell-associated Hyaluronan as an Unfavorable Prognostic Factor in Colorectal Cancer

    Kirsi Ropponen;Markku Tammi;Jyrki Parkkinen;Matti Eskelinen

  • High Levels of Stromal Hyaluronan Predict Poor Disease Outcome in Epithelial Ovarian Cancer

    Maarit A. Anttila;Raija H. Tammi;Markku I. Tammi;Kari J. Syrjänen

  • Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young beagle dogs.

    Ilkka Kiviranta;Markku Tammi;Jukka Jurvelin;Anna‐Marja Säämänen

  • Hyaluronan in human malignancies.

    Sironen Rk;Tammi M;Tammi R;Auvinen Pk

  • Hyaluronan-dependent pericellular matrix.

    Stephen P. Evanko;Markku I. Tammi;Raija H. Tammi;Thomas N. Wight

  • 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

    Anne Kultti;Sanna Pasonen-Seppänen;Marjo Jauhiainen;Kirsi J. Rilla

  • Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants.

    Jyrki Parkkinen;Jorma Ikonen;Mikko Lammi;Jukka Laakkonen

  • Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan.

    Raija H. Tammi;Anne Kultti;Veli-Matti Kosma;Risto Pirinen

  • Hyaluronan Enters Keratinocytes by a Novel Endocytic Route for Catabolism

    Raija H. Tammi;Raija H. Tammi;Kirsi Rilla;Juha-Pekka Pienimäki;Donald K. MacCallum

  • Microspectrophotometric quantitation of glycosaminoglycans in articular cartilage sections stained with Safranin O

    Kiviranta I;Jurvelin J;Tammi M;Säämänen Am

  • Structure of the Regulatory Hyaluronan Binding Domain in the Inflammatory Leukocyte Homing Receptor CD44.

    Peter Teriete;Suneale Banerji;Martin Noble;Charles D. Blundell

  • Microanalysis of enzyme digests of hyaluronan and chondroitin/dermatan sulfate by fluorophore-assisted carbohydrate electrophoresis (FACE).

    Anthony Calabro;Maria Benavides;Markku Tammi;Vincent C Hascall

  • Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro.

    Jyrki J. Parkkinen;Mikko J. Lammi;Heikki J. Helminen;Markku Tammi

  • Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe

    Raija. Tammi;James A. Ripellino;Richard U. Margolis;Markku. Tammi

  • Hyaluronan Metabolism in Skin

    Raija Tammi;Ulla M. Ågren;Anna-Liisa Tuhkanen;Markku Tammi

  • Chapter 25 – The Hyaluronan Synthases

    Paul H. Weigel

Frequent Co-Authors

Raija Tammi
Raija Tammi University of Eastern Finland
Heikki J. Helminen
Heikki J. Helminen University of Eastern Finland
Mikko J. Lammi
Mikko J. Lammi Umeå University
Jukka S. Jurvelin
Jukka S. Jurvelin University of Eastern Finland
Veli-Matti Kosma
Veli-Matti Kosma University of Eastern Finland
Vincent C. Hascall
Vincent C. Hascall Cleveland Clinic
Arto Urtti
Arto Urtti University of Eastern Finland
Carsten Carlberg
Carsten Carlberg University of Eastern Finland
Arto Mannermaa
Arto Mannermaa University of Eastern Finland
Alberto Passi
Alberto Passi University of Insubria

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