World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9641
World Ranking
16696
National Ranking
122

Paavo Honkakoski publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Paavo Honkakoski sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 141 publications — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Paavo Honkakoski D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Paavo Honkakoski sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 52 D-Index — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Paavo Honkakoski is affiliated with the University of Eastern Finland in Finland. Their research spans several interconnected fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, Honkakoski has contributed extensively to pharmacology, health, toxicology, mutagenesis, oncology, molecular biology, and ophthalmology.

The research topics covered by Honkakoski include:

  • Effects and risks of endocrine disrupting chemicals
  • Drug transport and resistance mechanisms
  • Pharmacogenetics and drug metabolism
  • Estrogen and related hormone effects
  • Amino acid enzymes and metabolism
  • Computational drug discovery methods
  • Hepatitis B virus studies

Their publication record comprises numerous papers published in several scientific journals. Frequent publication venues include:

  • Molecular Pharmaceutics
  • Drug Metabolism and Disposition
  • European Journal of Pharmaceutical Sciences
  • Molecular Psychiatry
  • Cells

Some of the recent papers authored or co-authored by Paavo Honkakoski include:

  • "Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches," 2021, Molecular Psychiatry
  • "Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR," 2020, Cells
  • "The EDCMET Project: Metabolic Effects of Endocrine Disruptors," 2020, International Journal of Molecular Sciences
  • "Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations," 2021, International Journal of Pharmaceutics
  • "Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors," 2021, Journal of Pharmacology and Experimental Therapeutics

Paavo Honkakoski collaborates frequently with a number of researchers consistently contributing to their joint scientific outputs. Notable co-authors include:

  • Anam Hammid
  • Jenni Küblbeck
  • Mika Reinisalo
  • Arto Urtti
  • Kim L. R. Brouwer

Best Publications

  • THE NUCLEAR ORPHAN RECEPTOR CAR-RETINOID X RECEPTOR HETERODIMER ACTIVATES THE PHENOBARBITAL-RESPONSIVE ENHANCER MODULE OF THE CYP2B GENE

    Paavo Honkakoski;Igor Zelko;Tatsuya Sueyoshi;Masahiko Negishi

  • The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene.

    Tatsuya Sueyoshi;Takeshi Kawamoto;Igor Zelko;Paavo Honkakoski

  • Inhibition and induction of human cytochrome P450 enzymes: current status.

    Olavi Pelkonen;Miia Turpeinen;Miia Turpeinen;Miia Turpeinen;Jukka Hakkola;Paavo Honkakoski

  • Regulation of cytochrome P450 (CYP) genes by nuclear receptors

    Paavo Honkakoski;Masahiko Negishi

  • Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes.

    Marika Ruponen;Seppo Rönkkö;Paavo Honkakoski;Jukka Pelkonen

  • Drug-activated nuclear receptors CAR and PXR.

    Paavo Honkakoski;Tatsuya Sueyoshi;Masahiko Negishi

  • ACTIVATION BY DIVERSE XENOCHEMICALS OF THE 51-BASE PAIR PHENOBARBITAL-RESPONSIVE ENHANCER MODULE IN THE CYP2B10 GENE

    Paavo Honkakoski;Rick Moore;Kimberly A. Washburn;Masahiko Negishi

  • High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans

    Anne-Marie Camus;Olivier Geneste;Paavo Honkakoski;Jean-Claude Béréziat

  • Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene.

    Paavo Honkakoski;Masahiko Negishi

  • Extracellular and intracellular barriers in non-viral gene delivery

    Marika Ruponen;Paavo Honkakoski;Seppo Rönkkö;Jukka Pelkonen

  • Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse.

    Hannu Raunio;Tuula Syngelmä;Markku Pasanen;Risto Juvonen

  • Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity

    Kati-Sisko Vellonen;Paavo Honkakoski;Arto Urtti

  • Characterization of Phenobarbital-inducible Mouse Cyp2b10 Gene Transcription in Primary Hepatocytes

    Paavo Honkakoski;Rick Moore;Jukka Gynther;Jukka Gynther;Masahiko Negishi

  • Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer.

    Marika Ruponen;Paavo Honkakoski;Markku Tammi;Arto Urtti

  • PEPTIDE-OLIGONUCLEOTIDE PHOSPHOROTHIOATE CONJUGATES WITH MEMBRANE TRANSLOCATION AND NUCLEAR LOCALIZATION PROPERTIES

    Maxim Antopolsky;Elena Azhayeva;Unni Tengvall;Seppo Auriola

  • Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

    Paavo Honkakoski;Masahiko Negishi

  • Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.

    Masahiko Negishi;Raija Lindberg;Barbara Burkhart;Takeshi Ichikawa

  • Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors.

    Pertti Pellinen;Paavo Honkakoski;Frej Stenbäck;Matthias Niemitz

  • Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors.

    Janne Mäkinen;Christian Frank;Johanna Jyrkkärinne;Jukka Gynther

  • Characterization of human cytochrome P450 induction by pesticides.

    Khaled Abass;Virpi Lämsä;Petri Reponen;Jenni Küblbeck

Frequent Co-Authors

Arto Urtti
Arto Urtti University of Eastern Finland
Olavi Pelkonen
Olavi Pelkonen University of Oulu
Hannu Raunio
Hannu Raunio University of Eastern Finland
Masahiko Negishi
Masahiko Negishi National Institutes of Health
Wolfgang Sippl
Wolfgang Sippl Martin Luther University Halle-Wittenberg
Anu Kauppinen
Anu Kauppinen University of Eastern Finland
Kai Kaarniranta
Kai Kaarniranta University of Eastern Finland
Seppo Auriola
Seppo Auriola University of Eastern Finland
Markku Tammi
Markku Tammi University of Eastern Finland
Kim L. R. Brouwer
Kim L. R. Brouwer University of North Carolina at Chapel Hill

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