What is he best known for?
The fields of study he is best known for:
Paavo Honkakoski mainly investigates Biochemistry, Molecular biology, Cytochrome P450, Gene expression and Nuclear receptor.
His Molecular biology study combines topics in areas such as Enhancer, Transcription, Messenger RNA and Phenobarbital.
Paavo Honkakoski has included themes like Drug metabolism, Microsome, Isozyme, Pharmacology and Cytochrome P450 reductase in his Cytochrome P450 study.
His Gene expression research is multidisciplinary, incorporating elements of Heparan sulfate, Regulation of gene expression, Intracellular and Transfection.
His research in the fields of Constitutive androstane receptor and Retinoid X receptor overlaps with other disciplines such as Receptor Cross-Talk.
His Constitutive androstane receptor research includes themes of Pregnane X receptor and Nuclear receptor co-repressor 1.
His most cited work include:
- THE NUCLEAR ORPHAN RECEPTOR CAR-RETINOID X RECEPTOR HETERODIMER ACTIVATES THE PHENOBARBITAL-RESPONSIVE ENHANCER MODULE OF THE CYP2B GENE (644 citations)
- The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. (604 citations)
- Regulation of cytochrome P450 (CYP) genes by nuclear receptors (426 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Biochemistry, Cytochrome P450, Molecular biology, Constitutive androstane receptor and Nuclear receptor.
Biochemistry connects with themes related to Androstane in his study.
The Cytochrome P450 study combines topics in areas such as Enzyme inducer, Drug metabolism, Microsome, Isozyme and Pharmacology.
His research on Molecular biology also deals with topics like
- Gene expression and related Transfection and Regulation of gene expression,
- Phenobarbital which connect with Benzphetamine.
His research in Constitutive androstane receptor intersects with topics in Retinoid X receptor, Cell biology, Pregnane X receptor, Computational biology and Corepressor.
His research integrates issues of Receptor, Ligand and Docking in his study of Nuclear receptor.
He most often published in these fields:
- Biochemistry (47.33%)
- Cytochrome P450 (33.59%)
- Molecular biology (27.48%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (16.79%)
- Biochemistry (47.33%)
- Drug metabolism (16.79%)
In recent papers he was focusing on the following fields of study:
Paavo Honkakoski focuses on Cell biology, Biochemistry, Drug metabolism, Constitutive androstane receptor and Nuclear receptor.
His Biochemistry research incorporates elements of Phenacetin and Drug.
His biological study spans a wide range of topics, including Regulation of gene expression and Pregnane X receptor.
His Regulation of gene expression research is multidisciplinary, relying on both Cell signaling, Gene expression and Epidermal growth factor receptor.
Paavo Honkakoski has researched Pregnane X receptor in several fields, including Drug development, Reverse transfection, Transfection, Molecular biology and Reporter gene.
A large part of his Nuclear receptor studies is devoted to Retinoid X receptor.
Between 2013 and 2021, his most popular works were:
- Regulation of gene expression by CAR: an update. (47 citations)
- Regulation of gene expression by CAR: an update. (47 citations)
- Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation. (42 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cell biology, Inflammation, Biochemistry, Retinal pigment epithelium and Cell culture.
His Cell biology study integrates concerns from other disciplines, such as Molecular biology and In vitro, Matrigel.
His Inflammation research focuses on subjects like Oxidative stress, which are linked to Fisetin, Luteolin, Proinflammatory cytokine and Pharmacology.
His is doing research in Cytochrome P450 and Receptor, both of which are found in Biochemistry.
His Cytochrome P450 research includes elements of Nuclear receptor, Constitutive androstane receptor, Regulation of gene expression and Epidermal growth factor receptor.
His studies deal with areas such as Intestinal absorption, Isozyme, Androstane and Intestinal epithelium as well as Cell culture.
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