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Immunology

D-Index
44
Citations
10297
World Ranking
4755
National Ranking
2137

Overview

John M. Routes is affiliated with the Medical College of Wisconsin in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with contributions spanning 25 publications in each area.

Routes' work delves into several subfields, including Immunology, Pulmonary and Respiratory Medicine, Hematology, Genetics, and Infectious Diseases. Central topics covered in their research include Immunodeficiency and Autoimmune Disorders, Blood disorders and treatments, Cystic Fibrosis Research Advances, Immune Cell Function and Interaction, Blood groups and transfusion, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, and T-cell and B-cell Immunology.

Frequent coauthors collaborating with Routes include:

  • James Verbsky
  • Kathleen E. Sullivan
  • Charlotte Cunningham-Rundles
  • Jennifer M. Puck
  • Shanmuganathan Chandrakasan

Their research has appeared in several venues, notably:

  • Journal of Clinical Immunology
  • Journal of Allergy and Clinical Immunology
  • American Journal of Tropical Medicine and Hygiene
  • The Lancet
  • The Journal of Experimental Medicine

Key recent papers include:

  • "All together to Fight COVID-19" (2020) published in the American Journal of Tropical Medicine and Hygiene
  • "Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium" (2023) published in The Lancet
  • "Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients" (2021) published in The Journal of Experimental Medicine
  • "Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency" (2020) published in the Journal of Allergy and Clinical Immunology
  • "Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies" (2020) published in Blood

Best Publications

  • International consensus document (icon): common variable immunodeficiency disorders

    Francisco A. Bonilla;Isil Barlan;Helen Chapel;Beatriz Tavares Costa-Carvalho

  • Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.

    Elizabeth A Worthey;Alan N Mayer;Alan N Mayer;Grant D Syverson;Daniel Helbling

  • Practice parameter for the diagnosis and management of primary immunodeficiency

    Francisco A. Bonilla;David A. Khan;Zuhair K. Ballas;Javier Chinen

  • Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States

    Antonia Kwan;Roshini S. Abraham;Robert Currier;Amy Brower

  • Practice parameter for the diagnosis and management of primary immunodeficiency.

    Francisco A. Bonilla;I. Leonard Bernstein;David A. Khan;Zuhair K. Ballas

  • Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency

    Christopher A. Bates;Misoo C. Ellison;David A. Lynch;Carlyne D. Cool

  • Expression of human herpesvirus 8 in primary pulmonary hypertension.

    Carlyne D Cool;Pradeep R Rai;Michael E Yeager;Daniel Hernandez-Saavedra

  • Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

    Chao Yang;Jason R. Siebert;Robert Burns;Zachary J. Gerbec

  • Statewide Newborn Screening for Severe T-Cell Lymphopenia

    John M. Routes;William J. Grossman;James Verbsky;Ronald H. Laessig

  • Development of a routine newborn screening protocol for severe combined immunodeficiency

    Mei W. Baker;William J. Grossman;Ronald H. Laessig;Gary L. Hoffman

  • Use of Combination Chemotherapy for Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease (GLILD) in Patients with Common Variable Immunodeficiency (CVID)

    Nicole M. Chase;James W. Verbsky;Mary K. Hintermeyer;Jill K. Waukau

  • Possible role of human herpesvirus 8 in the lymphoproliferative disorders in common variable immunodeficiency

    William H. Wheat;Carlyne D. Cool;Yoshikazu Morimoto;Pradeep R. Rai

  • Global study of primary immunodeficiency diseases (PI)—diagnosis, treatment, and economic impact: an updated report from the Jeffrey Modell Foundation

    Vicki Modell;Bonnie Gee;David B. Lewis;Jordan S. Orange

  • Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract.

    Anil Nanda;Maeve O'Connor;Miriam Anand;Stephen C. Dreskin

  • Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts

    William T. Shearer;Thomas A. Fleisher;Rebecca H. Buckley;Zuhair Ballas

  • Newborn screening for severe combined immunodeficiency; the Wisconsin experience (2008-2011).

    James W. Verbsky;Mei W. Baker;William J. Grossman;Mary Hintermeyer

  • Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation

    M. Teresa de la Morena;David Leonard;Troy R. Torgerson;Otavio Cabral-Marques

  • Granulomatous disease in common variable immunodeficiency.

    Yoshikazu Morimoto;John M Routes

  • Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.

    Claire Aguilar;Christelle Lenoir;Christelle Lenoir;Nathalie Lambert;Bernadette Bègue

  • Granulomatous and lymphocytic interstitial lung disease: a spectrum of pulmonary histopathologic lesions in common variable immunodeficiency—histologic and immunohistochemical analyses of 16 cases

    Nagarjun Rao;A. Craig Mackinnon;John M. Routes

Frequent Co-Authors

Charlotte Cunningham-Rundles
Charlotte Cunningham-Rundles Icahn School of Medicine at Mount Sinai
Francisco A. Bonilla
Francisco A. Bonilla Boston Children's Hospital
Hans D. Ochs
Hans D. Ochs University of Washington
Jennifer M. Puck
Jennifer M. Puck University of California, San Francisco
Jordan S. Orange
Jordan S. Orange University of Pennsylvania
William T. Shearer
William T. Shearer Baylor College of Medicine
Larry Borish
Larry Borish University of Virginia
Kevin K. Brown
Kevin K. Brown National Jewish Health
Carlyne D. Cool
Carlyne D. Cool University of Colorado Denver
Ulrich Broeckel
Ulrich Broeckel Medical College of Wisconsin

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