D-Index & Metrics Best Publications

Edward A. Sausville

University of Maryland, Baltimore
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Medicine D-index 79 Citations 24,766 255 World Ranking 12308 National Ranking 6415

Overview

What is he best known for?

The fields of study Edward A. Sausville is best known for:

Enzyme
Gene
Cyclin-dependent kinase 2

His research ties Endocrinology and Vasopressin together. His Endocrinology study frequently draws connections to other fields, such as Oxytocin. His research is interdisciplinary, bridging the disciplines of Internal medicine and Oxytocin. As part of his studies on Internal medicine, Edward A. Sausville often connects relevant areas like Lung cancer. Edward A. Sausville conducted interdisciplinary study in his works that combined Lung cancer and Cancer research. He combines Cancer research and Genetics in his research. As part of his studies on Genetics, he often connects relevant areas like Vasopressin. Edward A. Sausville performs integrative Cell culture and Molecular biology research in his work. Edward A. Sausville integrates many fields, such as Molecular biology and Gene, in his works.

His most cited work include:

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. (438 citations)
The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line. (288 citations)

What are the main themes of his work throughout his whole career to date

His Toxicity study is within the categories of Phases of clinical research and Neutropenia. As part of his studies on Neutropenia, Edward A. Sausville often connects relevant subjects like Toxicity. Many of his studies on Gene involve topics that are commonly interrelated, such as Cyclin B. In his research, he performs multidisciplinary study on Cyclin B and Cyclin-dependent kinase. He merges Cyclin-dependent kinase with Cyclin D1 in his study. Cyclin D1 and Cell are commonly linked in his work. Cell is closely attributed to Cell cycle in his work. He integrates many fields, such as Cell cycle and CDK inhibitor, in his works. His study on CDK inhibitor is mostly dedicated to connecting different topics, such as Cell biology.

Edward A. Sausville most often published in these fields:

Gene (45.45%)
Genetics (36.36%)
Molecular biology (36.36%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Proteasome Inhibitors: A Novel Class of Potent and Effective Antitumor Agents

Julian Adams;Vito J. Palombella;Edward A. Sausville;Jill Johnson.
Cancer Research (1999)

2215 Citations

Flavopiridol Induces G1 Arrest with Inhibition of Cyclin-dependent Kinase (CDK) 2 and CDK4 in Human Breast Carcinoma Cells

Bradley A. Carlson;Marja M. Dubay;Edward A. Sausville;Leonardo Brizuela.
Cancer Research (1996)

795 Citations

Preclinical and Clinical Development of Cyclin-Dependent Kinase Modulators

Adrian M. Senderowicz;Edward A. Sausville.
Journal of the National Cancer Institute (2000)

746 Citations

Osteonecrosis of the Jaw in Multiple Myeloma Patients: Clinical Features and Risk Factors

Ashraf Badros;Dianna Weikel;Andrew Salama;Olga Goloubeva.
Journal of Clinical Oncology (2006)

735 Citations

Novel Proteasome Inhibitor PS-341 Inhibits Activation of Nuclear Factor-κB, Cell Survival, Tumor Growth, and Angiogenesis in Squamous Cell Carcinoma

John B. Sunwoo;Zhong Chen;Gang Dong;Ning Yeh.
Clinical Cancer Research (2001)

725 Citations

UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53

Qizhi Wang;Saijun Fan;Alan Eastman;Peter J. Worland.
Journal of the National Cancer Institute (1996)

675 Citations

Identification of Small Molecule Inhibitors of Hypoxia-inducible Factor 1 Transcriptional Activation Pathway

Annamaria Rapisarda;Badarch Uranchimeg;Dominic A. Scudiero;Mike Selby.
Cancer Research (2002)

667 Citations

Contributions of Human Tumor Xenografts to Anticancer Drug Development

Edward A. Sausville;Angelika M. Burger.
Cancer Research (2006)

617 Citations

Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation

Sudhir B Kondapaka;Sheo S Singh;Girija P Dasmahapatra;Edward A Sausville.
Molecular Cancer Therapeutics (2003)

552 Citations

Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

A M Senderowicz;D Headlee;S F Stinson;R M Lush.
Journal of Clinical Oncology (1998)

487 Citations

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Frequent Co-Authors

External Links

Personal Website for Edward A. Sausville