Jean-Marc Pascussi

Overview

Best Publications

• Expression of CYP3A4, CYP2B6, andCYP2C9 Is Regulated by the Vitamin D Receptor Pathway in Primary Human Hepatocytes

  Lionel Drocourt;Jean-Claude Ourlin;Jean-Marc Pascussi;Patrick Maurel

  440
  Citations

• Induction of CYP2C genes in human hepatocytes in primary culture.

  Sabine Gerbal-Chaloin;Jean-Marc Pascussi;Lydiane Pichard-Garcia;Martine Daujat

  418
  Citations

• Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes

  Jean‐Marc Pascussi;Lionel Drocourt;Sabine Gerbal‐Chaloin;Jean‐Michel Fabre

  414
  Citations

• Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.

  Jean-Marc Pascussi;Lionel Drocourt;Jean-Michel Fabre;Patrick Maurel

  412
  Citations

• The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors

  J.M. Pascussi;S. Gerbal-Chaloin;L. Drocourt;P. Maurel

  410
  Citations

• Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia.

  Jean Marc Pascussi;Agnes Robert;Minh Nguyen;Odile Walrant-Debray

  355
  Citations

• Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor.

  Sabine Gerbal-Chaloin;Martine Daujat;Jean-Marc Pascussi;Lydiane Pichard-Garcia

  331
  Citations

• The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

  Jean-Marc Pascussi;Sabine Gerbal-Chaloin;Cédric Duret;Martine Daujat-Chavanieu

  319
  Citations

• Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.

  Jean-Marc Pascussi;Sabine Gerbal-Chaloin;Lydiane Pichard-Garcia;Martine Daujat

  314
  Citations

• Dexamethasone Enhances Constitutive Androstane Receptor Expression in Human Hepatocytes: Consequences on Cytochrome P450 Gene Regulation

  Jean-Marc Pascussi;Sabine Gerbal-Chaloin;Jean-Michel Fabre;Patrick Maurel

  296
  Citations

• Xenoreceptors CAR and PXR Activation and Consequences on Lipid Metabolism, Glucose Homeostasis, and Inflammatory Response

  Amelie Carla Moreau;Marie José Vilarem;Patrick Maurel;Jean-Marc Pascussi

  283
  Citations

• Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system.

  Géraldine Lemaire;Wissem Mnif;Jean-Marc Pascussi;Arnaud Pillon

  214
  Citations

• Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent

  Sonia Molina;Valerie Castet;Lydiane Pichard-Garcia;Czeslaw Wychowski

  202
  Citations

• Interleukin 1β inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance

  Eric Assenat;Sabine Gerbal-Chaloin;Dominique Larrey;Jean Saric

  193
  Citations

• Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture

  Fanny Grillet;Elsa Bayet;Elsa Bayet;Elsa Bayet;Olivia Villeronce;Olivia Villeronce;Olivia Villeronce;Luke Zappia

  192
  Citations

• Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds

  Vanessa Delfosse;Vanessa Delfosse;Vanessa Delfosse;Béatrice Dendele;Tiphaine Huet;Tiphaine Huet;Tiphaine Huet;Marina Grimaldi

  167
  Citations

• Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study†

  Pascal G. P. Martin;Hervé Guillou;Frédéric Lasserre;Sébastien Déjean

  164
  Citations

• Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck.

  M Pelosi;V Di Bartolo;V Mounier;D Mège

  160
  Citations

• Evidence for the Presence of a Functional Pregnane X Receptor Response Element in the CYP3A7 Promoter Gene

  Jean-Marc Pascussi;Youssef Jounaidi;Lionel Drocourt;Jacques Domergue

  157
  Citations

• The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity.

  Jean Claude Ourlin;Fredéric Lasserre;Thierry Pineau;Jean Michel Fabre

  155
  Citations