World's Best Scientists 2026 revealed!

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Microbiology

D-Index
60
Citations
13011
World Ranking
3123
National Ranking
179

Overview

Philippe Halfon is affiliated with Université Paris Cité in France and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology.

Their primary fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these main disciplines, subfields of study are centered on:

  • Infectious Diseases
  • Epidemiology
  • Molecular Biology
  • Hepatology
  • Neurology

Major research topics covered by Halfon include:

  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Autophagy in Disease and Therapy
  • Long-Term Effects of COVID-19
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Gut microbiota and health

Halfon's publication record involves various journals and repositories, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • PLoS ONE
  • Research Square (Research Square)
  • Viruses

Some recent papers authored or co-authored by Halfon include:

  • "Monocytes and Macrophages, Targets of Severe Acute Respiratory Syndrome Coronavirus 2: The Clue for Coronavirus Disease 2019 Immunoparalysis" (2021, The Journal of Infectious Diseases)
  • "A Granulocytic Signature Identifies COVID-19 and Its Severity" (2020, The Journal of Infectious Diseases)
  • "GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions" (2021, Autophagy)
  • "Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis" (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • "Gut microbiota in systemic lupus erythematosus patients and lupus mouse model: a cross species comparative analysis for biomarker discovery" (2022, Frontiers in Immunology)

The scientist has frequently collaborated with a group of co-authors including:

  • Soraya Mezouar
  • Guillaume Pénaranda
  • Eloïne Bestion
  • Anne Plauzolles
  • Jean-Louis Mège

Best Publications

  • Drug-resistance genotyping in HIV-1 therapy: the VIRAD APT randomi sed controlled trial

    J. Durant;P. Clevenbergh;P. Halfon;P. Delgiudice

  • Meta-analyses of FibroTest diagnostic value in chronic liver disease

    Thierry Poynard;Rachel Morra;Philippe Halfon;Laurent Castera

  • Hepatitis C virus resistance to protease inhibitors.

    Philippe Halfon;Stephen Locarnini

  • CpG methylation controls reactivation of HIV from latency.

    Jana Blazkova;Katerina Trejbalova;Katerina Trejbalova;Françoise Gondois-Rey;Philippe Halfon

  • CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.

    Vivien Béziat;Vivien Béziat;Vivien Béziat;Olav Dalgard;Tarik Asselah;Philippe Halfon

  • HCV direct‐acting antiviral agents: the best interferon‐free combinations

    Raymond Schinazi;Philippe Halfon;Patrick Marcellin;Tarik Asselah

  • Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy: pharmacological data from the Viradapt Study.

    J Durant;P Clevenbergh;R Garraffo;P Halfon

  • Standardization of ROC Curve Areas for Diagnostic Evaluation of Liver Fibrosis Markers Based on Prevalences of Fibrosis Stages

    Thierry Poynard;Philippe Halfon;Laurent Castera;Mona Munteanu

  • SAFE biopsy: A validated method for large-scale staging of liver fibrosis in chronic hepatitis C

    Giada Sebastiani;Philippe Halfon;Laurent Castera;Stanislas Pol

  • Accuracy of hyaluronic acid level for predicting liver fibrosis stages in patients with hepatitis C virus.

    Philippe Halfon;Marc Bourlière;Guillaume Pénaranda;Romaric Deydier

  • Independent Prospective Multicenter Validation of Biochemical Markers (Fibrotest-Actitest) for the Prediction of Liver Fibrosis and Activity in Patients with Chronic Hepatitis C: The Fibropaca Study

    Philippe Halfon;Marc Bourliere;Romaric Deydier;Danielle Botta-Fridlund

  • Discrepancies between Protease Inhibitor Concentrations and Viral Load in Reservoirs and Sanctuary Sites in Human Immunodeficiency Virus-Infected Patients

    Caroline Solas;Alain Lafeuillade;Philippe Halfon;Stéphane Chadapaud

  • Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection

    Etienne Patin;Etienne Patin;Zoltán Kutalik;Zoltán Kutalik;Julien Guergnon;Stéphanie Bibert

  • Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations.

    Jérôme Deval;Kirsten L. White;Michael D. Miller;Neil T. Parkin

  • Prediction of oesophageal varices in hepatic cirrhosis by simple serum non-invasive markers: Results of a multicenter, large-scale study

    Giada Sebastiani;Diego Tempesta;Giovanna Fattovich;Laurent Castera

  • Monocytes and Macrophages, Targets of Severe Acute Respiratory Syndrome Coronavirus 2: The Clue for Coronavirus Disease 2019 Immunoparalysis.

    Asma Boumaza;Soraya Mezouar;Eloïne Bestion

  • Impact of various handling and storage conditions on quantitative detection of hepatitis C virus RNA

    Philippe Halfon;Hacène Khiri;Victoria Gérolami;Marc Bourlière

  • Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid-based cytology in primary cervical cancer screening: the FASE study

    Joseph Monsonego;Michael G. Hudgens;Laurent Zerat;Jean Claude Zerat

  • Changing of hepatitis C virus genotype patterns in France at the beginning of the third millenium: The GEMHEP GenoCII Study.

    C. Payan;F. Roudot-Thoraval;P. Marcellin;N. Bled

  • How to measure the diagnostic accuracy of noninvasive liver fibrosis indices: the area under the ROC curve revisited.

    Jerome Lambert;Philippe Halfon;Guillaume Penaranda;Pierre Bedossa

  • Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C

    Philippe Halfon;Yannick Bacq;Anne De Muret;Guillaume Penaranda

  • Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.

    Jérôme Boursier;Yannick Bacq;Philippe Halfon;Vincent Leroy

Frequent Co-Authors

Marc Bourlière
Marc Bourlière Hôpital Saint Joseph
Patrice Cacoub
Patrice Cacoub Sorbonne University
Stanislas Pol
Stanislas Pol Université Paris Cité
Albert Tran
Albert Tran Inserm : Institut national de la santé et de la recherche médicale
Thierry Poynard
Thierry Poynard Sorbonne University
Patrick Marcellin
Patrick Marcellin Université Paris Cité
Fabrice Carrat
Fabrice Carrat Sorbonne University
Daniel Olive
Daniel Olive Aix-Marseille University
Philippe Colson
Philippe Colson Aix-Marseille University
Isabelle Poizot-Martin
Isabelle Poizot-Martin Aix-Marseille University

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