David H. Margulies mostly deals with Major histocompatibility complex, Molecular biology, MHC class I, Peptide and Antigen. His Major histocompatibility complex research includes elements of Cytotoxic T cell, CD8, Stereochemistry and T-cell receptor. David H. Margulies focuses mostly in the field of Molecular biology, narrowing it down to matters related to Cell culture and, in some cases, Neoplasm, Tissue culture, Endocrinology and Autoimmunity.
His studies in MHC class I integrate themes in fields like Receptor, Macromolecule and Cell biology. His studies deal with areas such as Epitope, Peptide sequence, Human leukocyte antigen and Monoclonal antibody as well as Peptide. His research in Antigen intersects with topics in Antibody, Gene and Antigen presentation.
David H. Margulies focuses on Major histocompatibility complex, MHC class I, Molecular biology, Antigen and Peptide. His study looks at the relationship between Major histocompatibility complex and fields such as T-cell receptor, as well as how they intersect with chemical problems. The concepts of his MHC class I study are interwoven with issues in Natural killer cell, Receptor, Peptide sequence, Peptide binding and Cell biology.
His study in Molecular biology is interdisciplinary in nature, drawing from both Gene, Epitope, Antibody, Monoclonal antibody and CTL*. His Antigen research includes themes of Recombinant DNA and Transfection. His biological study spans a wide range of topics, including Biophysics, Stereochemistry, Antigen presentation and Binding site.
His scientific interests lie mostly in MHC class I, Major histocompatibility complex, Peptide, Cell biology and Biophysics. His MHC class I research integrates issues from Natural killer cell, Chaperone and Molecular biology. His Major histocompatibility complex research incorporates themes from T cell, Antigen presentation and Virology.
The study incorporates disciplines such as Epitope and Cytotoxic T cell in addition to Virology. His Peptide study is concerned with Biochemistry in general. His Cell biology research is multidisciplinary, relying on both Receptor, Antigen processing, Antigen and T-cell receptor.
His primary scientific interests are in Major histocompatibility complex, MHC class I, Cell biology, Tapasin and Peptide. David H. Margulies has researched Major histocompatibility complex in several fields, including Allosteric regulation, Antigen presentation and Virology. His MHC class I research incorporates elements of Natural killer cell and Function.
David H. Margulies has included themes like Receptor, Toll-like receptor, Molecular biology and T-cell receptor in his Cell biology study. His study in Antigen extends to T-cell receptor with its themes. David H. Margulies combines subjects such as Biophysics, Peptide binding and Peptide sequence with his study of Peptide.
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The biochemistry and cell biology of antigen processing and presentation
R N Germain;D H Margulies.
Annual Review of Immunology (1993)
A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells.
Malcolm L. Gefter;David H. Margulies;Matthew D. Scharff.
Somatic Cell and Molecular Genetics (1977)
T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity
Maripat Corr;Alfred E. Slanetz;Lisa F. Boyd;Marie T. Jelonek.
Structure and Function of Natural Killer Cell Receptors: Multiple Molecular Solutions to Self, Nonself Discrimination*
Kannan Natarajan;Nazzareno Dimasi;Jian Wang;Roy A. Mariuzza.
Annual Review of Immunology (2002)
Enhanced Antigen-Specific Antitumor Immunity with Altered Peptide Ligands that Stabilize the MHC-Peptide-TCR Complex
Jill E Slansky;Frédérique M Rattis;Lisa F Boyd;Tarek Fahmy.
Crystal Structure of a Lectin-Like Natural Killer Cell Receptor Bound to its Mhc Class I Ligand
José Tormo;Kannan Natarajan;David H. Margulies;Roy A. Mariuzza.
Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues.
Weisan Chen;Sergei Khilko;John Fecondo;David H. Margulies.
Journal of Experimental Medicine (1994)
Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens
Glen A. Evans;David H. Margulies;Benjamin Shykind;J. G. Seidman.
The TLR3 signaling complex forms by cooperative receptor dimerization
Joshua N. Leonard;Rodolfo Ghirlando;Janine Askins;Jessica K. Bell.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld
G A Evans;D H Margulies;R D Camerini-Otero;K Ozato.
Proceedings of the National Academy of Sciences of the United States of America (1982)
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