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Claudio O. Gualerzi

Claudio O. Gualerzi

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
14515
World Ranking
1336
National Ranking
23

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Claudio O. Gualerzi is affiliated with the University of Camerino in Italy and primarily works within the field of Biochemistry, Genetics and Molecular Biology. Their research output focuses prominently on Molecular Biology, Genetics, Atomic and Molecular Physics and Optics, Microbiology, and Immunology.

The scientist's main topics of research include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Bacterial Genetics and Biotechnology
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • Invertebrate Immune Response Mechanisms
  • RNA Research and Splicing

Gualerzi's recent publications highlight ongoing work in these areas. Notable recent papers include:

  • "The Ribosome as a Switchboard for Bacterial Stress Response," 2021, published in Frontiers in Microbiology
  • "Disparate Phenotypes Resulting from Mutations of a Single Histidine in Switch II of Geobacillus stearothermophilus Translation Initiation Factor IF2," 2020, published in International Journal of Molecular Sciences
  • "Prokaryotic Expression and Functional Verification of Antimicrobial Peptide LRGG," 2024, published both in Preprints.org and International Journal of Molecular Sciences
  • "A binding site for the antibiotic GE81112 in the ribosomal mRNA channel," 2024, published in bioRxiv (Cold Spring Harbor Laboratory)

These publications reflect a focus on molecular mechanisms in bacterial systems, antimicrobial peptides, and ribosomal function.

Frequent coauthors in Gualerzi's body of work include:

  • Chengguang He
  • Anna Maria Giuliodori
  • Attilio Fabbretti
  • Hongxia Ma
  • Andreas Schedlbauer

The scientist's research has appeared repeatedly in several venues, with multiple articles in the International Journal of Molecular Sciences, as well as publications in bioRxiv, Frontiers in Microbiology, Preprints.org, and SciPost Physics.

Claudio Gualerzi holds membership in the European Molecular Biology Organization (EMBO), reflecting recognition within the scientific community.

Best Publications

  • Initiation of mRNA translation in prokaryotes.

    Claudio O. Gualerzi;Cynthia L. Pon

  • Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature‐dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H‐NS

    Maurizio Falconi;Bianca Colonna;Gianni Prosseda;Gioacchino Micheli

  • Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS

    A. La Teana;Anna Brandi;Maurizio Falconi;Roberto Spurio

  • Translational control of prokaryotic gene expression

    John E.G. McCarthy;Claudio Gualerzi

  • Transcriptional and post-transcriptional control of cold-shock genes

    Claudio O Gualerzi;Anna Maria Giuliodori;Cynthia L Pon

  • High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes

    Benjamin Lang;Nicolas Blot;Emeline Bouffartigues;Malcolm Buckle

  • The cspA mRNA Is a Thermosensor that Modulates Translation of the Cold-Shock Protein CspA

    Anna Maria Giuliodori;Fabio Di Pietro;Stefano Marzi;Benoit Masquida

  • Leaderless mRNAs in bacteria: surprises in ribosomal recruitment and translational control.

    Isabella Moll;Sonja Grill;Claudio O Gualerzi;Udo Bläsi

  • Structure of the 30S translation initiation complex

    Angelita Simonetti;Stefano Marzi;Alexander G. Myasnikov;Attilio Fabbretti

  • POST-TRANSCRIPTIONAL REGULATION OF CSPA EXPRESSION IN ESCHERICHIA COLI

    Anna Brandi;Paola Pietroni;Claudio O. Gualerzi;Cynthia L. Pon

  • Specific protection of 16 S rRNA by translationalinitiation factors

    Danesh Moazed;Raymond R. Samaha;Claudio Gualerzi;Harry F. Noller

  • The oligomeric structure of nucleoid protein H-NS is necessary for recognition of intrinsically curved DNA and for DNA bending

    Roberto Spurio;Maurizio Falconi;Anna Brandi;Cynthia L. Pon

  • Selection of the mRNA translation initiation region by Escherichia coli ribosomes.

    Raffaele A. Calogero;Cynthia L. Pon;Maria A. Canonaco;Claudio O. Gualerzi

  • Lethal overproduction of the Escherichia coli nucleoid protein H-NS: ultramicroscopic and molecular autopsy.

    Roberto Spurio;M. Dürrenberger;Maurizio Falconi;A. La Teana

  • The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor.

    P Milon;E Tischenko;Jerneja Tomsic;E Caserta

  • The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif

    M. Sette;P. van Tilborg;Roberto Spurio;R. Kaptein

  • The virF promoter in Shigella: more than just a curved DNA stretch.

    Gianni Prosseda;Maurizio Falconi;Mara Giangrossi;Claudio O. Gualerzi

  • Massive presence of the Escherichia coli 'major cold-shock protein' CspA under non-stress conditions.

    Anna Brandi;Roberto Spurio;Claudio O. Gualerzi;Cynthia L. Pon

  • Initiation of mRNA translation in bacteria: structural and dynamic aspects

    Claudio O. Gualerzi;Cynthia L. Pon

  • Conformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome.

    Alexander G Myasnikov;Stefano Marzi;Stefano Marzi;Angelita Simonetti;Anna Maria Giuliodori

Frequent Co-Authors

Cynthia L. Pon
Cynthia L. Pon University of Camerino
Rolf Boelens
Rolf Boelens Utrecht University
Raffaele A. Calogero
Raffaele A. Calogero University of Turin
Stefano Donadio
Stefano Donadio University of Wisconsin–Madison
Marina V. Rodnina
Marina V. Rodnina Max Planck Society
Udo Bläsi
Udo Bläsi University of Vienna
Albert E. Dahlberg
Albert E. Dahlberg Brown University
Wolfgang Wintermeyer
Wolfgang Wintermeyer Max Planck Society
Thomas A. Steitz
Thomas A. Steitz Yale University
Linda K. Medlin
Linda K. Medlin Alfred Wegener Institute for Polar and Marine Research

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