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Biology and Biochemistry

D-Index
76
Citations
14905
World Ranking
5168
National Ranking
2458

Overview

Howard Robinson is affiliated with Brookhaven National Laboratory in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Chemistry, reflecting a research focus that integrates molecular and chemical perspectives.

Their subfields of study include Molecular Biology, Organic Chemistry, Cancer Research, Genetics, and Nutrition and Dietetics. These areas contribute to the broader understanding of biochemical and chemical processes at the molecular level and their applications.

The main topics of Howard Robinson's research encompass:

  • Phosphodiesterase function and regulation
  • Chemical synthesis and alkaloids
  • Synthesis and Catalytic Reactions
  • Bacterial biofilms and quorum sensing
  • Genomics and Phylogenetic Studies
  • Synthesis and Biological Activity
  • Bacterial Genetics and Biotechnology

Howard Robinson has contributed to scientific literature in several publication venues, with a notable frequency in:

  • UNC Libraries
  • New Blackfriars
  • Journal of Biological Chemistry
  • Inorganic Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers by Howard Robinson include:

  • PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation, 2020, Journal of Biological Chemistry
  • Multiple Conformations of Phosphodiesterase-5: IMPLICATIONS FOR ENZYME FUNCTION AND DRUG DEVELOPMENT, 2021, UNC Libraries
  • Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain, 2020, UNC Libraries
  • Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin, 2023, Inorganic Chemistry
  • Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis, 2020, UNC Libraries

Throughout their career, Howard Robinson has collaborated frequently with a number of researchers, including Hengming Ke, Huanchen Wang, Robert Op, Richard Op, and Simon Op. These collaborations reflect a network of scholarly interaction, particularly in areas related to phosphodiesterase research and related biochemical studies.

Best Publications

  • The Fas–FADD death domain complex structure unravels signalling by receptor clustering

    Fiona L. Scott;Boguslaw Stec;Cristina Pop;Małgorzata K. Dobaczewska

  • Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding

    Robert D. Fisher;Hyo Young Chung;Qianting Zhai;Howard Robinson

  • Rationally tuning the reduction potential of a single cupredoxin beyond the natural range.

    Nicholas M. Marshall;Dewain K. Garner;Tiffany D. Wilson;Yi Gui Gao

  • The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.

    Andreas Förster;Eugene I. Masters;Frank G. Whitby;Howard Robinson

  • Rational design of a structural and functional nitric oxide reductase

    Natasha Yeung;Ying Wu Lin;Yi Gui Gao;Xuan Zhao

  • Structure and ubiquitin binding of the ubiquitin interacting motif

    Robert D. Fisher;Bin Wang;Steven L. Alam;Daniel S. Higginson

  • The hyperthermophile chromosomal protein Sac7d sharply kinks DNA

    Howard Robinson;Yi-Gui Gao;Bradford S. McCrary;Stephen P. Edmondson

  • Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme

    Hui Wei;Zidong Wang;Jiong Zhang;Stephen House

  • An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

    John C. Whitney;Dennis Quentin;Shin Sawai;Michele LeRoux

  • Structure of the mid-region of tropomyosin: bending and binding sites for actin.

    Jerry H. Brown;Zhaocai Zhou;Ludmilla Reshetnikova;Howard Robinson

  • Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation

    Yonghui Zhang;Rong Cao;Fenglin Yin;Michael P. Hudock

  • The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA

    Yi-Gui Gao;Shao-Yu Su;Howard Robinson;Savita Padmanabhan

  • Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development

    Huanchen Wang;Yudong Liu;Qing Huai;Jiwen Cai;Jiwen Cai

  • Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein.

    Brian N. Kelly;Sampson Kyere;Isaac Kinde;Chun Tang

  • Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening

    Kianoush Sadre-Bazzaz;Frank G. Whitby;Howard Robinson;Tim Formosa

  • Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.

    Jae Sung Woo;Jae Hong Lim;Ho Chul Shin;Min Kang Suh

  • Crystal structure of DJ-1/RS and implication on familial Parkinson's disease

    Qing Huai;Yingjie Sun;Huanchen Wang;Lih Shen Chin

  • Neomycin, Spermine and Hexaamminecobalt(III) Share Common Structural Motifs in Converting B- to A-DNA

    Howard Robinson;Andrew H.-J. Wang

  • Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa.

    James F. Parsons;Bryan T. Greenhagen;Katherine Shi;Kelly Calabrese

  • Structural insight into substrate specificity of phosphodiesterase 10.

    Huanchen Wang;Yudong Liu;Jing Hou;Jing Hou;Meiyan Zheng

Frequent Co-Authors

P. Lynne Howell
P. Lynne Howell University of Toronto
Christopher P. Hill
Christopher P. Hill University of Utah
Hengming Ke
Hengming Ke University of North Carolina at Chapel Hill
Yi Lu
Yi Lu University of Illinois at Urbana-Champaign
David H. Margulies
David H. Margulies National Institutes of Health
Eric Oldfield
Eric Oldfield University of Illinois at Urbana-Champaign
Wesley I. Sundquist
Wesley I. Sundquist University of Utah
Mark R. Chance
Mark R. Chance Case Western Reserve University
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Donald C. Sheppard
Donald C. Sheppard McGill University

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