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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
21403
World Ranking
4336
National Ranking
2112

Overview

Mark R. Chance is affiliated with Case Western Reserve University in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with notable contributions in Molecular Biology, Spectroscopy, Physiology, Immunology, and Materials Chemistry.

The scientist's work spans a variety of topics, including:

  • Advanced Proteomics Techniques and Applications
  • Bioinformatics and Genomic Networks
  • Mass Spectrometry Techniques and Applications
  • Alzheimer's Disease Research and Treatments
  • Metabolomics and Mass Spectrometry Studies
  • Redox Biology and Oxidative Stress
  • Enzyme Structure and Function

Mark R. Chance has collaborated frequently with several colleagues, including Mehmet Koyutürk, Janna Kiselar, Daniela Schlatzer, Marzieh Ayati, and Serhan Yılmaz.

The scientist has contributed to various publication venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular & Cellular Proteomics
  • Journal of the American Society for Mass Spectrometry
  • Analytical Chemistry

Recent papers authored or co-authored by Mark R. Chance include:

  • Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution, 2020, Journal of Molecular Biology
  • GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis, 2021, Science Advances
  • Robust inference of kinase activity using functional networks, 2021, Nature Communications
  • Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism, 2020, Molecular & Cellular Proteomics
  • Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer's disease, 2020, Annals of Clinical and Translational Neurology

Best Publications

  • Protein production and purification.

    S Gräslund

  • Hydroxyl radical-mediated modification of proteins as probes for structural proteomics.

    Guozhong Xu;Mark R. Chance

  • Structural genomics: beyond the human genome project.

    Stephen K. Burley;Stephen K. Burley;Steven C. Almo;Jeffrey B. Bonanno;Jeffrey B. Bonanno;Malcolm Capel

  • RNA folding at millisecond intervals by synchrotron hydroxyl radical footprinting

    Bianca Sclavi;Michael Sullivan;Mark R. Chance;Michael Brenowitz

  • C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression.

    Jérôme Reboul;Philippe Vaglio;Jean François Rual;Jean François Rual;Philippe Lamesch;Philippe Lamesch

  • Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1.

    M F Summers;L E Henderson;M R Chance;J W Bess

  • Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

    Jinbo Yang;Jing Huang;Maupali Dasgupta;Nathan Sears

  • Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy

    Xin Chen;Zhengzhong Shao;Nebojsa S. Marinkovic;Lisa M. Miller

  • Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65

    Tao Lu;Mark W Jackson;Benlian Wang;Maojing Yang

  • Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

    Yongyou Zhang;Amar Desai;Sung Yeun Yang;Sung Yeun Yang;Ki Beom Bae;Ki Beom Bae

  • Radiolytic protein footprinting with mass spectrometry to probe the structure of macromolecular complexes.

    Keiji Takamoto;Mark R. Chance

  • In situ analysis of mineral content and crystallinity in bone using infrared micro-spectroscopy of the ν4 PO43− vibration

    Lisa M. Miller;Vidyasagar Vairavamurthy;Mark R. Chance;Richard Mendelsohn

  • Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

    Thomas E. Angel;Mark R. Chance;Krzysztof Palczewski

  • Millisecond radiolytic modification of peptides by synchrotron X-rays identified by mass spectrometry.

    Simin D. Maleknia;Michael Brenowitz;Mark R. Chance

  • Structural waters define a functional channel mediating activation of the GPCR, rhodopsin

    Thomas E. Angel;Sayan Gupta;Beata Elzbieta Jastrzebska;Krzysztof Palczewski

  • The KSEA App: a web-based tool for kinase activity inference from quantitative phosphoproteomics.

    Danica D Wiredja;Mehmet Koyutürk;Mark R Chance

  • Structural genomics: A pipeline for providing structures for the biologist

    Mark R. Chance;Anne R. Bresnick;Stephen K. Burley;Stephen K. Burley;Jian Sheng Jiang

  • The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

    Katarzyna Bulek;Caini Liu;Shadi Swaidani;Liwen Wang

  • Time-resolved synchrotron X-ray "footprinting", a new approach to the study of nucleic acid structure and function: application to protein-DNA interactions and RNA folding.

    Bianca Sclavi;Sarah Woodson;Michael Sullivan;Mark R. Chance

  • Assembly of a GPCR-G Protein Complex

    Yang Du;Nguyen Minh Duc;Søren G.F. Rasmussen;Daniel Hilger

Frequent Co-Authors

Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Michael Brenowitz
Michael Brenowitz Albert Einstein College of Medicine
Jill S. Barnholtz-Sloan
Jill S. Barnholtz-Sloan Case Western Reserve University
Stephen K. Burley
Stephen K. Burley Rutgers, The State University of New Jersey
Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Goutham Narla
Goutham Narla University of Michigan–Ann Arbor
Andrej Sali
Andrej Sali University of California, San Francisco
Lisa M. Miller
Lisa M. Miller Brookhaven National Laboratory
Irit Sagi
Irit Sagi Weizmann Institute of Science
James B. Leverenz
James B. Leverenz Cleveland Clinic

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