World's Best Scientists 2026 revealed!

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Chemistry

D-Index
55
Citations
7843
World Ranking
12418
National Ranking
3310

Biology and Biochemistry

D-Index
57
Citations
8579
World Ranking
14101
National Ranking
5946

Overview

Michael Brenowitz is affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology as a subfield.

The scientist's work covers several main topics including:

  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • Epigenetics and DNA Methylation
  • RNA Modifications and Cancer
  • Mass Spectrometry Techniques and Applications
  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms

Michael Brenowitz has published articles in a range of venues, frequently appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Analytical Chemistry
  • UNC Libraries
  • ACS Omega
  • Journal of Pharmaceutical Sciences

Notable recent papers include:

  • "Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis" (2020), published in ACS Omega
  • "Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Best Practices for Aggregate Quantitation of Antibody Therapeutics by Sedimentation Velocity Analytical Ultracentrifugation" (2022), published in Journal of Pharmaceutical Sciences
  • "INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication" (2021), published in Nature Communications
  • "High throughput and low bias DNA methylation and hydroxymethylation analysis by direct injection mass spectrometry" (2021), published in Analytica Chimica Acta

Frequent co-authors working with Michael Brenowitz include:

  • David Hayes
  • S. Garforth
  • Steven C. Almo
  • Yan Sun
  • Simone Sidoli

Best Publications

  • Quantitative DNase footprint titration: a method for studying protein-DNA interactions.

    Michael D. Brenowitz;Donald F. Senear;Madeline A. Shea;Gary K. Ackers

  • RNA folding at millisecond intervals by synchrotron hydroxyl radical footprinting

    Bianca Sclavi;Michael Sullivan;Mark R. Chance;Michael Brenowitz

  • Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging.

    Daria M. Shcherbakova;Mikhail Baloban;Alexander V. Emelyanov;Michael Brenowitz

  • A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding.

    Nina Pastor;Harel Weinstein;Elizabeth Jamison;Michael Brenowitz

  • Millisecond radiolytic modification of peptides by synchrotron X-rays identified by mass spectrometry.

    Simin D. Maleknia;Michael Brenowitz;Mark R. Chance

  • Time-resolved synchrotron X-ray "footprinting", a new approach to the study of nucleic acid structure and function: application to protein-DNA interactions and RNA folding.

    Bianca Sclavi;Sarah Woodson;Michael Sullivan;Mark R. Chance

  • Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control

    Vivek L. Patel;Somdeb Mitra;Richard Harris;Adina R. Buxbaum

  • Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations.

    Keiji Takamoto;Rhiju Das;Qin He;Sebastian Doniach

  • Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity

    Meng Chiao Ho;Meng Chiao Ho;Carola Wilczek;Jeffrey B. Bonanno;Li Xing

  • Quaternary solution structures of galectins-1, -3, and -7

    Stephanie Morris;Nisar Ahmad;Sabine Andre;Herbert Kaltner

  • The Oct-2 protein binds cooperatively to adjacent octamer sites.

    Jonathan H. LeBowitz;Roger G. Clerc;Michael Brenowitz;Phillip A. Sharp

  • Thermodynamic and kinetic characterization of the binding of the TATA binding protein to the adenovirus E4 promoter.

    Victoria Petri;Mark Hsieh;Michael Brenowitz

  • Probing the structural dynamics of nucleic acids by quantitative time-resolved and equilibrium hydroxyl radical "footprinting".

    Michael Brenowitz;Mark R. Chance;Gauri Dhavan;Keiji Takamoto

  • Determination of Macromolecular Folding and Structure by Synchrotron X-Ray Radiolysis Techniques

    Simin D. Maleknia;Corie Y. Ralston;Michael D. Brenowitz;Kevin M. Downard

  • 'Footprinting' proteins on DNA with peroxonitrous acid.

    Peter A. King;Elizabeth Jamison;Daniel Strahs;Vernon E. Anderson

  • High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis

    Somdeb Mitra;Inna V. Shcherbakova;Russ B. Altman;Michael Brenowitz

  • Fast Fenton footprinting: a laboratory-based method for the time-resolved analysis of DNA, RNA and proteins

    Inna Shcherbakova;Somdeb Mitra;Robert H. Beer;Michael Brenowitz

  • Concerted binding and bending of DNA by Eschericia coli integration host factor

    Gauri M Dhavan;Donald M Crothers;Mark R Chance;Michael Brenowitz

  • Monovalent cations mediate formation of native tertiary structure of the Tetrahymena thermophila ribozyme.

    Keiji Takamoto;Qin He;Stephanie Morris;Mark R. Chance

  • Productive folding to the native state by a group II intron ribozyme.

    Jennifer F Swisher;Linhui J Su;Michael Brenowitz;Vernon E Anderson

  • DNA structure and flexibility in the sequence-specific binding of papillomavirus E2 proteins

    Christina S. Hines;Colin Meghoo;Sanjay Shetty;Markus Biburger

Frequent Co-Authors

Mark R. Chance
Mark R. Chance Case Western Reserve University
Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Anna Marie Pyle
Anna Marie Pyle Yale University
Sarah A. Woodson
Sarah A. Woodson Johns Hopkins University
David Cowburn
David Cowburn Albert Einstein College of Medicine
Celia Bonaventura
Celia Bonaventura Duke University
Russ B. Altman
Russ B. Altman Stanford University
Kartik Chandran
Kartik Chandran Albert Einstein College of Medicine
John M. Greally
John M. Greally Albert Einstein College of Medicine
Matt Law
Matt Law University of California, Irvine

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