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Genetics

D-Index
76
Citations
19705
World Ranking
1834
National Ranking
843

Overview

John M. Greally is affiliated with the Albert Einstein College of Medicine in the United States. Their research spans fields primarily within Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. Their scholarly output includes over 130 publications related to these domains.

The subfields of study in which John M. Greally has contributed most extensively include:

  • Molecular Biology
  • Genetics
  • Pediatrics, Perinatology and Child Health
  • Public Health, Environmental and Occupational Health
  • Pathology and Forensic Medicine

The main topics of John M. Greally's research cover diverse and specialized areas such as:

  • Genomics and Rare Diseases
  • BRCA gene mutations in cancer
  • Epigenetics and DNA Methylation
  • Genomic variations and chromosomal abnormalities
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Ethics in Clinical Research

John M. Greally has frequently published in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine
  • Genetics in Medicine Open
  • The American Journal of Human Genetics
  • PLoS Genetics

Recent published papers attributed to John M. Greally include:

  • Recommendations for clinical interpretation of variants found in non-coding regions of the genome (2022), Genome Medicine
  • Variant Classification Concordance using the ACMG-AMP Variant Interpretation Guidelines across Nine Genomic Implementation Research Studies (2020), The American Journal of Human Genetics
  • The SEQC2 epigenomics quality control (EpiQC) study (2021), Genome Biology
  • The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data (2020), BMC Bioinformatics
  • Spliceosome malfunction causes neurodevelopmental disorders with overlapping features (2023), Journal of Clinical Investigation

Collaboration is a prominent aspect of John M. Greally's career. They have frequently co-authored work with researchers such as:

  • Bruce D. Gelb
  • Eimear E. Kenny
  • Melissa Wasserstein
  • Noura S. Abul-Husn
  • Sabrina A. Suckiel

Best Publications

  • Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

    Aaron D. Goldberg;Laura A. Banaszynski;Kyung Min Noh;Peter W. Lewis

  • DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

    Maria E. Figueroa;Sanne Lugthart;Yushan Li;Claudia Erpelinck-Verschueren

  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

    Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Matthew J. Wakefield;Bronwen Aken;Chris T. Amemiya

  • Comparative isoschizomer profiling of cytosine methylation: The HELP assay

    Batbayar Khulan;Reid F. Thompson;Kenny Ye;Melissa J. Fazzari

  • EPIGENOMICS: BEYOND CpG ISLANDS

    Melissa J. Fazzari;John M. Greally

  • Recommendations for the design and analysis of epigenome-wide association studies

    Karin B Michels;Alexandra M Binder;Sarah Dedeurwaerder;Charles B Epstein

  • MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

    Maria E. Figueroa;Lucy Skrabanek;Yushan Li;Anchalee Jiemjit

  • LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

    Jennifer C. Chow;Constance Ciaudo;Melissa J. Fazzari;Nathan Mise;Nathan Mise

  • Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR

    Stella Maris Ranuncolo;Jose M Polo;Jamil Dierov;Michael Singer

  • Identification of Four Highly Conserved Genes between Breakpoint Hotspots BP1 and BP2 of the Prader-Willi/Angelman Syndromes Deletion Region That Have Undergone Evolutionary Transposition Mediated by Flanking Duplicons

    J. H. Chai;D. P. Locke;J. M. Greally;J. H.M. Knoll

  • Associating cellular epigenetic models with human phenotypes

    Tuuli Lappalainen;John M. Greally

  • Epigenome-wide Association Studies and the Interpretation of Disease -Omics.

    Ewan Birney;George Davey Smith;John M. Greally

  • Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

    James P Reddington;Sara M Perricone;Colm E Nestor;Colm E Nestor;Judith Reichmann

  • Hypomethylation of Noncoding DNA Regions and Overexpression of the Long Noncoding RNA, AFAP1-AS1, in Barrett’s Esophagus and Esophageal Adenocarcinoma

    Wenjing Wu;Wenjing Wu;Tushar D. Bhagat;Xue Yang;Jee Hoon Song

  • Genetic recombination is targeted towards gene promoter regions in dogs.

    Adam Auton;Ying Rui Li;Jeffrey Kidd;Kyle Oliveira

  • Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

    Britta Will;Li Zhou;Thomas O. Vogler;Susanna Ben-Neriah

  • Tissue-specific dysregulation of DNA methylation in aging

    Reid F. Thompson;Gil Atzmon;Ciprian Gheorghe;Hong Qian Liang

  • Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

    Yi-An Ko;Davoud Mohtat;Masako Suzuki;Ae Seo Deok Park

  • A stain upon the silence: genes escaping X inactivation

    Carolyn J. Brown;John M. Greally

  • Epigenetics, cellular memory and gene regulation.

    Steven Henikoff;John M. Greally

Frequent Co-Authors

Amit Verma
Amit Verma Albert Einstein College of Medicine
Ari Melnick
Ari Melnick Cornell University
Ulrich Steidl
Ulrich Steidl Albert Einstein College of Medicine
Maria E. Figueroa
Maria E. Figueroa University of Miami
Amittha Wickrema
Amittha Wickrema University of Chicago
Cathal Seoighe
Cathal Seoighe University of Galway
Robert D. Nicholls
Robert D. Nicholls University of Pittsburgh
Deyou Zheng
Deyou Zheng Albert Einstein College of Medicine
Eimear E. Kenny
Eimear E. Kenny Icahn School of Medicine at Mount Sinai
Jeffrey A. Sosman
Jeffrey A. Sosman Northwestern University

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