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Cathal Seoighe

Cathal Seoighe

D-Index & Metrics

Molecular Biology

D-Index
43
Citations
10454
World Ranking
2956
National Ranking
4

Overview

Cathal Seoighe is a researcher affiliated with the National University of Ireland, Galway, specializing in biochemistry, genetics, and molecular biology. Their work encompasses a broad range of topics within these fields, with a particular focus on molecular biology, genetics, cancer research, immunology, and oncology.

Their recent publications reflect a focus on genetic and genomic research, with notable papers including:

  • Perspectives on Allele-Specific Expression, 2021, Annual Review of Biomedical Data Science
  • ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition, 2020, Cell Reports
  • Bias and inconsistency in the estimation of tumour mutation burden, 2022, BMC Cancer
  • Somatic mutations inferred from RNA-seq data highlight the contribution of replication timing to mutation rate variation in a model plant, 2023, Genetics
  • Controlling for background genetic effects using polygenic scores improves the power of genome-wide association studies, 2021, Scientific Reports

Their research covers several main topics, including:

  • Cancer Genomics and Diagnostics
  • Genetic Associations and Epidemiology
  • Genetic Mapping and Diversity in Plants and Animals
  • Bioinformatics and Genomic Networks
  • Gene expression and cancer classification
  • Pancreatic and Hepatic Oncology Research
  • Genomics and Phylogenetic Studies

Seoighe frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Research Square, European Neuropsychopharmacology, HRB Open Research, and SSRN Electronic Journal. Their work has appeared most often in bioRxiv with eight publications.

Collaboration is a significant aspect of their research, with frequent coauthors including Dónal O'Shea, Declan Bennett, Derek W. Morris, Siobhán Cleary, and Mohammad A. Makrooni. These collaborations contribute to studies across molecular biology, genetics, and cancer research areas.

Best Publications

  • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

    Brandon F. Keele;Elena E. Giorgi;Elena E. Giorgi;Jesus F. Salazar-Gonzalez;Julie M. Decker

  • Quantitating the Multiplicity of Infection with Human Immunodeficiency Virus Type 1 Subtype C Reveals a Non-Poisson Distribution of Transmitted Variants

    M. R. Abrahams;J. A. Anderson;E. E. Giorgi;E. E. Giorgi;C. Seoighe

  • Genome duplication led to highly selective expansion of the Arabidopsis thaliana proteome.

    Cathal Seoighe;Cathal Seoighe;Chris Gehring

  • Genome-wide analysis of the structure of the South African Coloured Population in the Western Cape

    Erika de Wit;Wayne Delport;Wayne Delport;Chimusa E. Rugamika;Ayton Meintjes

  • Robust inference of positive selection from recombining coding sequences

    Konrad Scheffler;Darren P. Martin;Cathal Seoighe

  • Yeast genome evolution in the post-genome era.

    Cathal Seoighe;Kenneth H Wolfe

  • CellMix: a comprehensive toolbox for gene expression deconvolution

    Renaud Gaujoux;Cathal Seoighe

  • HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.

    Natasha Wood;Tanmoy Bhattacharya;Tanmoy Bhattacharya;Brandon F. Keele;Elena Giorgi;Elena Giorgi

  • Prevalence of small inversions in yeast gene order evolution

    Cathal Seoighe;Nancy Federspiel;Ted Jones;Nancy Hansen

  • Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage

    Denis R. Chopera;Zenda Woodman;Koleka Mlisana;Mandla Mlotshwa

  • Extent of genomic rearrangement after genome duplication in yeast.

    Cathal Seoighe;Kenneth H. Wolfe

  • RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships

    Julie Nadel;Rodoniki Athanasiadou;Rodoniki Athanasiadou;Christophe Lemetre;Christophe Lemetre;N. Ari Wijetunga

  • Comparison of Viral Env Proteins from Acute and Chronic Infections with Subtype C Human Immunodeficiency Virus Type 1 Identifies Differences in Glycosylation and CCR5 Utilization and Suggests a New Strategy for Immunogen Design

    Li Hua Ping;Sarah B. Joseph;Jeffrey A. Anderson;Jeffrey A. Anderson;Melissa Rose Abrahams

  • Semi-supervised Nonnegative Matrix Factorization for gene expression deconvolution: A case study

    Renaud Gaujoux;Cathal Seoighe

  • Updated map of duplicated regions in the yeast genome.

    Cathal Seoighe;Kenneth H. Wolfe

  • Gene-Set Analysis is Severely Biased When Applied to Genome-wide Methylation Data

    Paul Geeleher;Lori Hartnett;Laurance J. Egan;Aaron Golden

  • The shared genomic architecture of human nucleolar organizer regions

    Ioanna Floutsakou;Saumya Agrawal;Thong T. Nguyen;Cathal Seoighe

  • Evolution of gene order and chromosome number in Saccharomyces, Kluyveromyces and related fungi.

    Robert S. Keogh;Cathal Seoighe;Kenneth H. Wolfe

  • Gametophytic selection in Arabidopsis thaliana supports the selective model of intron length reduction.

    Cathal Seoighe;Chris Gehring;Laurence D Hurst

  • Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants (Journal of Virology (2009) 83, 8, (3556-3567))

    M. R. Abrahams;J. A. Anderson;E. E. Giorgi;C. Seoighe

Frequent Co-Authors

Bette T. Korber
Bette T. Korber Los Alamos National Laboratory
Carolyn Williamson
Carolyn Williamson University of Cape Town
Kenneth H. Wolfe
Kenneth H. Wolfe University College Dublin
Winston Hide
Winston Hide Harvard Medical School
John M. Greally
John M. Greally Albert Einstein College of Medicine
George M. Shaw
George M. Shaw University of Pennsylvania
Salim S. Abdool Karim
Salim S. Abdool Karim Centre for the AIDS Programme of Research in South Africa
Lynn Morris
Lynn Morris University of the Witwatersrand
Koleka Mlisana
Koleka Mlisana National Health Laboratory Service
Beatrice H. Hahn
Beatrice H. Hahn University of Pennsylvania

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