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Immunology

D-Index
132
Citations
56218
World Ranking
220
National Ranking
144

Medicine

D-Index
132
Citations
56220
World Ranking
2333
National Ranking
1318

Research.com Recognitions

  • 1995 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jay A. Berzofsky is affiliated with the National Institutes of Health in the United States. Their research spans several fields, primarily focusing on immunology, microbiology, medicine, and biochemistry, genetics, and molecular biology.

The main subfields where they have contributed include immunology, oncology, molecular biology, infectious diseases, and epidemiology. Their work centers on topics such as immunotherapy and immune responses, immune cell function and interaction, cancer immunotherapy and biomarkers, SARS-CoV-2 and COVID-19 research, vaccines and immunoinformatics approaches, COVID-19 clinical research studies, and CAR-T cell therapy research.

Among the recent publications, the following papers highlight the scope and focus of their research:

  • Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD (2022, Cancer Cell)
  • Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank (2020, Neuro-Oncology)
  • Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques (2021, JCI Insight)
  • Potential SARS-CoV-2 Immune Correlates of Protection in Infection and Vaccine Immunization (2021, Pathogens)
  • SARS-CoV-2 Spike Protein Suppresses ACE2 and Type I Interferon Expression in Primary Cells From Macaque Lung Bronchoalveolar Lavage (2021, Frontiers in Immunology)

The frequent co-authors collaborating with Jay A. Berzofsky include:

  • Purevdorj B. Olkhanud
  • Yongjun Sui
  • Hoyoung Maeng
  • Jianping Li
  • Tanya Hoang

Their work is often published in venues such as The Journal of Immunology, Frontiers in Immunology, Regular and Young Investigator Award Abstracts, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, and JCI Insight, reflecting a broad engagement across immunology and related fields.

Jay A. Berzofsky has received recognition through awards such as the Fellow of the American Association for the Advancement of Science (AAAS) in 1995 and membership in the Association of American Physicians.

Best Publications

  • Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

    Chi Ma;Miaojun Han;Bernd Heinrich;Qiong Fu

  • Human retroviruses and AIDS, 1991. [CONTAINS GLOSSARY]

    G. Myers;B. Korber;J.A. Berzofsky;G.N. Pavlakis

  • THE ANTIGENIC STRUCTURE OF PROTEINS: A REAPPRAISAL

    D C Benjamin;J A Berzofsky;I J East;F R Gurd

  • Human retroviruses and AIDS 1996. A compilation and analysis of nucleic acid and amino acid sequences

    G. Myers;B. Foley;B. Korber

  • NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

    Masaki Terabe;So Matsui;Nancy Noben-Trauth;Hangjiong Chen

  • Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

    Rong Zeng;Rosanne Spolski;Steven E. Finkelstein;Sang Kon Oh

  • Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

    James L. Cornette;Kemp B. Cease;Hanah Margalit;John L. Spouge

  • Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance Abrogation Prevents Tumor Recurrence

    Masaki Terabe;So Matsui;Jong-Myun Park;Mizuko Mamura

  • T-cell antigenic sites tend to be amphipathic structures.

    Charles Delisi;Jay A. Berzofsky

  • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy

    Martha A. Alexander-Miller;Graham R. Leggatt;Jay A. Berzofsky

  • Intrinsic and Extrinsic Factors in Protein Antigenic Structure

    Jay A. Berzofsky

  • Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs.

    H Takahashi;T Takeshita;B Morein;S Putney

  • Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.

    Alan Sher;Ricardo T. Gazzinelli;Isabelle P. Oswald;Mario Clerici

  • Prediction of immunodominant helper T cell antigenic sites from the primary sequence.

    H Margalit;J L Spouge;J L Cornette;K B Cease

  • An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

    Hidemi Takahashi;Joseph Cohen;Anne Hosmalin;Kemp B. Cease

  • Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

    Jason A. Hall;Jason A. Hall;Nicolas Bouladoux;Cheng Ming Sun;Elizabeth A. Wohlfert

  • Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma

    John C. Morris;Antoinette R. Tan;Thomas E. Olencki;Geoffrey I. Shapiro

  • Cell-Mediated Immune Response to Human Immunodeficiency Virus (HIV) Type 1 in Seronegative Homosexual Men with Recent Sexual Exposure to HIV-1

    Mario Clerici;Janis V. Giorgi;Janis V. Giorgi;Janis V. Giorgi;Chen Cheng Chou;Vaheideh K. Gudeman;Vaheideh K. Gudeman;Vaheideh K. Gudeman

  • Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

    Mario Clerici;Daniel R. Lucey;Jay A. Berzofsky;Ligia A. Pinto

  • Strategies for designing and optimizing new generation vaccines

    Jay A. Berzofsky;Jeffrey D. Ahlers;Igor M. Belyakov

Frequent Co-Authors

Masaki Terabe
Masaki Terabe National Institutes of Health
Igor M. Belyakov
Igor M. Belyakov University of Michigan–Ann Arbor
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Mario Clerici
Mario Clerici University of Milan
Charles DeLisi
Charles DeLisi Boston University
David H. Margulies
David H. Margulies National Institutes of Health
Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
Bernard Moss
Bernard Moss National Institutes of Health
John C. Morris
John C. Morris Washington University in St. Louis
Hanah Margalit
Hanah Margalit Hebrew University of Jerusalem

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