What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
Tsuyoshi Yokoi mainly investigates Molecular biology, Biochemistry, CYP2A6, Pharmacology and Allele.
His Molecular biology research is multidisciplinary, incorporating elements of Luciferase, Messenger RNA, microRNA, Regulation of gene expression and Isozyme.
His work in CYP2A6 addresses subjects such as Nicotine, which are connected to disciplines such as Endocrinology.
His Pharmacology research is multidisciplinary, relying on both In vitro and Physiology.
His work is dedicated to discovering how Allele, Genotype are connected with Polymerase, 5' flanking region, Polymerase chain reaction and Intron and other disciplines.
His studies deal with areas such as Metabolite, Microsome and In vivo as well as Cytochrome P450.
His most cited work include:
- Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs (441 citations)
- Cytochrome P450-mediated metabolism of estrogens and its regulation in human (407 citations)
- Role of human cytochrome P4502A6 in C-oxidation of nicotine. (374 citations)
What are the main themes of his work throughout his whole career to date?
Tsuyoshi Yokoi focuses on Pharmacology, Molecular biology, Biochemistry, Internal medicine and Cytochrome P450.
His Pharmacology study frequently draws connections between adjacent fields such as In vivo.
His work carried out in the field of Molecular biology brings together such families of science as CYP2A6, Luciferase and Messenger RNA, Gene, Allele.
His Allele study combines topics in areas such as Genotype and Cotinine, Nicotine.
His Internal medicine study combines topics from a wide range of disciplines, such as Endocrinology, Antibody and Cardiology.
His Microsome research includes themes of Metabolite, Carboxylesterase and Hydroxylation.
He most often published in these fields:
- Pharmacology (37.98%)
- Molecular biology (24.55%)
- Biochemistry (24.29%)
What were the highlights of his more recent work (between 2015-2021)?
- Liver injury (17.83%)
- Internal medicine (21.45%)
- Pharmacology (37.98%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Liver injury, Internal medicine, Pharmacology, Cardiology and microRNA.
His research on Liver injury also deals with topics like
- Oxidative stress which is related to area like Cytochrome P450,
- Immune system together with Cell culture,
- Metabolite which intersects with area such as CYP3A4.
His research on Internal medicine often connects related topics like Endocrinology.
Tsuyoshi Yokoi has included themes like Receptor and Kupffer cell in his Endocrinology study.
His work on Drug as part of general Pharmacology research is often related to Lovastatin, thus linking different fields of science.
Tsuyoshi Yokoi combines subjects such as Carcinogenesis and Cancer research with his study of microRNA.
Between 2015 and 2021, his most popular works were:
- Toxicological potential of acyl glucuronides and its assessment. (25 citations)
- Structure and Protein-Protein Interactions of Human UDP-Glucuronosyltransferases. (24 citations)
- Late-Onset Fulminant Myocarditis With Immune Checkpoint Inhibitor Nivolumab (20 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
His main research concerns Liver injury, Pharmacology, Toxicity, Endocrinology and Internal medicine.
The concepts of his Liver injury study are interwoven with issues in Glutathione, Metabolite, Biomarker, Alanine transaminase and In vivo.
In his work, Oxidative stress is strongly intertwined with CYP3A4, which is a subfield of In vivo.
His study in Pharmacology is interdisciplinary in nature, drawing from both Acute kidney injury and Skeletal muscle.
His research in Toxicity intersects with topics in Viability assay, Glucuronidation and Drug development, Drug.
His Endocrinology study also includes
- Receptor that intertwine with fields like Ischemic preconditioning,
- Immune system which is related to area like Kinase and MAPK/ERK pathway.
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