Yoshihiko Funae

Overview

Best Publications

• Role of human cytochrome P4502A6 in C-oxidation of nicotine.

  M. Nakajima;T. Yamamoto;K.-I. Nunoya;T. Yokoi

  591
  Citations

• cDNA cloning and structure of mouse putative Ah receptor

  M. Ema;K. Sogawa;N. Watanabe;Y. Chujoh

  529
  Citations

• Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.

  M. Nakajima;T. Yamamoto;K.-I. Nunoya;T. Yokoi

  399
  Citations

• Dopamine Formation from Tyramine by CYP2D6

  Toyoko Hiroi;Susumu Imaoka;Yoshihiko Funae

  311
  Citations

• Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat.

  Susumu Imaoka;Takao Yamada;Toyoko Hiroi;Koji Hayashi

  290
  Citations

• Changes in amounts of cytochrome P450 isozymes and levels of catalytic activities in hepatic and renal microsomes of rats with streptozocin-induced diabetes

  N Shimojo;T Ishizaki;S Imaoka;Y Funae

  238
  Citations

• Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography

  Yoshihiko Funae;Susumu Imaoka

  224
  Citations

• Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.

  Takanori Hashizume;Susumu Imaoka;Masashi Mise;Yoshiaki Terauchi

  219
  Citations

• A COMPARISON OF HEPATIC CYTOCHROME P450 PROTEIN EXPRESSION BETWEEN INFANCY AND POSTINFANCY

  Tomonori Tateishi;Hironori Nakura;Masako Asoh;Minoru Watanabe

  209
  Citations

• Lidocaine metabolism by human cytochrome P-450s purified from hepatic microsomes: comparison of those with rat hepatic cytochrome P-450s.

  S Imaoka;K Enomoto;Y Oda;A Asada

  201
  Citations

• Irreversible Inhibition of Cytochrome P450 by Nitric Oxide

  Yukiko Minamiyama;Shigekazu Takemura;Susumu Imaoka;Yoshihiko Funae

  198
  Citations

• Role of phospholipids in reconstituted cytochrome P 450 3A form and mechanism of their activation of catalytic activity

  Susumu Imaoka;Yoshio Imai;Tsutomu Shimada;Yoshihiko Funae

  180
  Citations

• Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation

  Susumu Imaoka;Yoshitake Terano;Yoshihiko Funae

  176
  Citations

• Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes

  Toshipumi Shiraga;Hiroji Matsuda;Kazuko Nagase;Kazuhide Iwasaki

  173
  Citations

• Apigenin suppresses the expression of VEGF, an important factor for angiogenesis, in endothelial cells via degradation of HIF-1α protein

  Mayuko Osada;Susumu Imaoka;Yoshihiko Funae

  163
  Citations

• Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats.

  Yoshihiko Funae;Susumu Imaoka

  157
  Citations

• A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)- cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)

  Ken ichi Nunoya;Tsuyoshi Yokoi;Kanzo Kimura;Kazuaki Inoue

  156
  Citations

• Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha.

  T Aoyama;J P Hardwick;S Imaoka;Y Funae

  155
  Citations

• Age-dependent expression of cytochrome P-450s in rat liver.

  Susumu Imaoka;Shoichi Fujita;Yoshihiko Funae

  149
  Citations

• Sterol 14-Demethylase P450 (P45014DM*) Is One of the Most Ancient and Conserved P450 Species

  Yuri Aoyama;Mitsuhide Noshiro;Osamu Gotoh;Susumu Imaoka

  143
  Citations