D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 12,468 357 World Ranking 6021 National Ranking 424

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Yasushi Yamazoe focuses on Biochemistry, Microsome, Molecular biology, Cytochrome P450 and Internal medicine. His Biochemistry study is mostly concerned with Cytochrome, Enzyme, Amino acid, Carcinogen and Aryl sulfotransferase. His Microsome research includes elements of Furanocoumarin, Stereochemistry, Arachidonic acid and Hydroxylation.

His Molecular biology study combines topics from a wide range of disciplines, such as Nucleic acid sequence and Complementary DNA, cDNA library, Peptide sequence, Messenger RNA. His Cytochrome P450 research incorporates elements of Cysteamine, Alloxan, Isozyme and Grapefruit juice. His biological study spans a wide range of topics, including Endocrinology and Farnesoid X receptor.

His most cited work include:

  • Sex difference of cytochrome P-450 in the rat: purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats. (223 citations)
  • Role of Furanocoumarin Derivatives on Grapefruit Juice-Mediated Inhibition of Human CYP3A Activity (220 citations)
  • Inhibition Selectivity of Grapefruit Juice Components on Human Cytochromes P450 (197 citations)

What are the main themes of his work throughout his whole career to date?

Yasushi Yamazoe mainly investigates Biochemistry, Endocrinology, Internal medicine, Molecular biology and Microsome. His study in Enzyme, Cytochrome, Sulfotransferase, Carcinogen and Amino acid is carried out as part of his Biochemistry studies. His research integrates issues of Metabolite, Reductase and Indole test in his study of Cytochrome.

The study incorporates disciplines such as Complementary DNA, Nucleic acid sequence, Messenger RNA, Gene and Pregnane X receptor in addition to Molecular biology. His Microsome research integrates issues from Cytochrome P450 and Hydroxylation. His work carried out in the field of Cytochrome P450 brings together such families of science as Phenobarbital, Pharmacology and Isozyme.

He most often published in these fields:

  • Biochemistry (42.86%)
  • Endocrinology (21.01%)
  • Internal medicine (21.01%)

What were the highlights of his more recent work (between 2008-2021)?

  • Endocrinology (21.01%)
  • Internal medicine (21.01%)
  • Pharmacology (15.69%)

In recent papers he was focusing on the following fields of study:

Yasushi Yamazoe mainly focuses on Endocrinology, Internal medicine, Pharmacology, Molecular biology and Biochemistry. The various areas that he examines in his Endocrinology study include Receptor and Fatty acid. His Internal medicine research is multidisciplinary, incorporating perspectives in Messenger RNA, Signal transduction and Hepatocyte.

The Pharmacology study combines topics in areas such as Testicular toxicity, In vitro, Sulfation, Rat liver and CYP3A4. Yasushi Yamazoe has researched Molecular biology in several fields, including Pregnane X receptor, Nuclear receptor, Retinoid X receptor, Transactivation and Sterol regulatory element-binding protein 2. His work on Sulfotransferase, Enzyme, Cytochrome P450 and Hepatic bile is typically connected to Antibacterial drug as part of general Biochemistry study, connecting several disciplines of science.

Between 2008 and 2021, his most popular works were:

  • Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5'-flanking region. (63 citations)
  • Administration of Ampicillin Elevates Hepatic Primary Bile Acid Synthesis through Suppression of Ileal Fibroblast Growth Factor 15 Expression (55 citations)
  • Fibroblast Growth Factor 19 Treatment Ameliorates Disruption of Hepatic Lipid Metabolism in Farnesoid X Receptor (Fxr)-Null Mice (50 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Molecular biology, Pregnane X receptor, Endocrinology, Internal medicine and Nuclear receptor. Yasushi Yamazoe interconnects Sterol regulatory element-binding protein 2, Transcription factor, Transactivation and Immunoprecipitation in the investigation of issues within Molecular biology. His Pregnane X receptor study is concerned with the field of Biochemistry as a whole.

His work in Endocrinology addresses subjects such as Farnesoid X receptor, which are connected to disciplines such as Cholesterol 7 alpha-hydroxylase and Oxidative phosphorylation. His work deals with themes such as Microsome and Glutathione, which intersect with Internal medicine. His studies deal with areas such as Electrophoretic mobility shift assay and Cell biology as well as Nuclear receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Sex difference of cytochrome P-450 in the rat: purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats.

Tetsuya Kamataki;Kaori Maeda;Yasushi Yamazoe;Tsuneji Nagai.
Archives of Biochemistry and Biophysics (1983)

334 Citations

Role of Furanocoumarin Derivatives on Grapefruit Juice-Mediated Inhibition of Human CYP3A Activity

Lian-Qing Guo;Katsuyuki Fukuda;Tomihisa Ohta;Yasushi Yamazoe.
Drug Metabolism and Disposition (2000)

333 Citations

Inhibition Selectivity of Grapefruit Juice Components on Human Cytochromes P450

Wichittra Tassaneeyakul;Lian-Qing Guo;Katsuyuki Fukuda;Tomihisa Ohta.
Archives of Biochemistry and Biophysics (2000)

298 Citations

Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction

Katsuyuki Fukuda;Tomihisa Ohta;Yoshiteru Oshima;Noriko Ohashi.
Pharmacogenetics (1997)

263 Citations

Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone.

Y Yamazoe;M Shimada;N Murayama;R Kato.
Journal of Biological Chemistry (1987)

229 Citations

Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates.

Ryuichi Kato;Yasushi Yamazoe.
Japanese Journal of Cancer Research (1987)

212 Citations

Sex-specific cytochrome P450 as a cause of sex- and species-related differences in drug toxicity.

R. Kato;Y. Yamazoe.
Toxicology Letters (1992)

207 Citations

Structural similarity and diversity of sulfotransferases

Yasushi Yamazoe;Kiyoshi Nagata;Shogo Ozawa;Ryuichi Kato.
Chemico-Biological Interactions (1994)

189 Citations

Role of Human Hepatocyte Nuclear Factor 4α in the Expression of Drug-Metabolizing Enzymes and Transporters in Human Hepatocytes Assessed by Use of Small Interfering RNA

Yoshiteru Kamiyama;Yoshiteru Kamiyama;Tsutomu Matsubara;Kouichi Yoshinari;Kiyoshi Nagata;Kiyoshi Nagata.
Drug Metabolism and Pharmacokinetics (2007)

172 Citations

Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2-acetylaminofluorene.

Kiyoshi Nagata;Shogo Ozawa;Masaaki Miyata;Miki Shimada.
Journal of Biological Chemistry (1993)

168 Citations

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