Shogo Ozawa

Overview

Best Publications

• Functional Analysis of SNPs Variants of BCRP/ABCG2

  Chihiro Kondo;Hiroshi Suzuki;Masaya Itoda;Shogo Ozawa

  370
  Citations

• Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

  Hironobu Minami;Kimie Sai;Mayumi Saeki;Yoshiro Saito

  333
  Citations

• UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.

  Kimie Sai;Mayumi Saeki;Yoshiro Saito;Shogo Ozawa

  291
  Citations

• Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

  Hiromi Fukushima-Uesaka;Yoshiro Saito;Hidemi Watanabe;Kisho Shiseki

  245
  Citations

• Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

  Emiko Sugiyama;Nahoko Kaniwa;Su-Ryang Kim;Ruri Kikura-Hanajiri

  224
  Citations

• Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1

  Shogo Ozawa;Akiko Soyama;Mayumi Saeki;Hiromi Fukushima-Uesaka

  206
  Citations

• Structural similarity and diversity of sulfotransferases

  Yasushi Yamazoe;Kiyoshi Nagata;Shogo Ozawa;Ryuichi Kato

  188
  Citations

• Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin

  N Hanioka;S Ozawa;H Jinno;M Ando

  187
  Citations

• Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

  Kimie Sai;Nahoko Kaniwa;Masaya Itoda;Yoshiro Saito

  173
  Citations

• Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2-acetylaminofluorene.

  Kiyoshi Nagata;Shogo Ozawa;Masaaki Miyata;Miki Shimada

  165
  Citations

• Decreased Expression of Cytochromes P450 1A2, 2E1, and 3A4 and Drug Transporters Na+-Taurocholate-Cotransporting Polypeptide, Organic Cation Transporter 1, and Organic Anion-Transporting Peptide-C Correlates with the Progression of Liver Fibrosis in Chronic Hepatitis C Patients

  Kenya Nakai;Hiromasa Tanaka;Kazuhiko Hanada;Hiroyasu Ogata

  159
  Citations

• Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

  Masakazu Hirouchi;Hiroshi Suzuki;Masaya Itoda;Shogo Ozawa

  155
  Citations

• Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism.

  Akiko Soyama;Yoshiro Saito;Nobumitsu Hanioka;Norie Murayama

  144
  Citations

• Cloning and sequence analysis of a rat liver cDNA encoding hydroxysteroid sulfotransferase

  Kenichiro Ogura;Jiro Kajita;Hiroyuki Narihata;Tadashi Watabe

  143
  Citations

• Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines.

  Shogo Ozawa;Yong Ming Tang;Yasushi Yamazoe;Ryuichi Kato

  139
  Citations

• Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals : an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28

  Masaya Itoda;Yoshiro Saito;Akiko Soyama;Mayumi Saeki

  133
  Citations

• cDNA cloning of the hydroxysteroid sulfotransferase STa sharing a strong homology in amino acid sequence with the senescence marker protein SMP-2 in rat livers.

  Kenichiro Ogura;Jiro Kajita;Hiroyuki Narihata;Tadashi Watabe

  133
  Citations

• Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.

  Satoru Koyano;Kouichi Kurose;Yoshiro Saito;Shogo Ozawa

  132
  Citations

• Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol.

  Susan Nowell;Christine B. Ambrosone;Shogo Ozawa;Stewart L. Macleod

  125
  Citations

• Severe Drug Toxicity Associated with a Single-Nucleotide Polymorphism of the Cytidine Deaminase Gene in a Japanese Cancer Patient Treated with Gemcitabine plus Cisplatin

  Kan Yonemori;Hideki Ueno;Takuji Okusaka;Noboru Yamamoto

  124
  Citations