What is he best known for?
The fields of study he is best known for:
Avigdor Shafferman mainly focuses on Stereochemistry, Acetylcholinesterase, Active center, Virology and Bacillus anthracis.
His Stereochemistry research incorporates elements of Amino acid, Hydrolase, Enzyme, Catalytic triad and Oxyanion hole.
His Acetylcholinesterase study is focused on Biochemistry in general.
His work deals with themes such as Paraoxon, Active site, Substrate, Allosteric regulation and Binding site, which intersect with Active center.
In general Virology study, his work on Virus, Vaccination and Antibody titer often relates to the realm of Population, thereby connecting several areas of interest.
His research in Bacillus anthracis intersects with topics in Plasmid, Microbiology and Virulence.
His most cited work include:
- Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II (264 citations)
- Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket. (241 citations)
- A Phase I Evaluation of the Safety and Immunogenicity of Vaccination with Recombinant gp160 in Patients with Early Human Immunodeficiency Virus Infection (211 citations)
What are the main themes of his work throughout his whole career to date?
Avigdor Shafferman mainly investigates Acetylcholinesterase, Virology, Microbiology, Stereochemistry and Biochemistry.
His Acetylcholinesterase study is concerned with the field of Enzyme as a whole.
His Virology study incorporates themes from Epitope, Antigen and Immune system.
His Microbiology research is multidisciplinary, incorporating elements of Francisella tularensis, Attenuated vaccine, Yersinia pestis, Virulence and Bacillus anthracis.
His study in Bacillus anthracis is interdisciplinary in nature, drawing from both Plasmid, In vivo and Toxin.
Avigdor Shafferman interconnects Transition state analog, Catalytic triad, Active site, Active center and Binding site in the investigation of issues within Stereochemistry.
He most often published in these fields:
- Acetylcholinesterase (28.87%)
- Virology (27.32%)
- Microbiology (23.71%)
What were the highlights of his more recent work (between 2006-2020)?
- Microbiology (23.71%)
- Virology (27.32%)
- Virulence (13.92%)
In recent papers he was focusing on the following fields of study:
Avigdor Shafferman spends much of his time researching Microbiology, Virology, Virulence, Bacillus anthracis and Immune system.
The study incorporates disciplines such as Francisella tularensis, Bacteria, Attenuated vaccine, Antibody and Yersinia pestis in addition to Microbiology.
His work on Vaccination as part of general Virology study is frequently connected to Mycobacterium tuberculosis, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Virulence study combines topics from a wide range of disciplines, such as Phenotype, Secretion, Mutant and Plasmid.
His study on Mutant is covered under Biochemistry.
The concepts of his Acetylcholinesterase study are interwoven with issues in Structure–activity relationship and Binding site.
Between 2006 and 2020, his most popular works were:
- Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses (106 citations)
- Identification of In Vivo-Expressed Immunogenic Proteins by Serological Proteome Analysis of the Bacillus anthracis Secretome (99 citations)
- Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection. (67 citations)
In his most recent research, the most cited papers focused on:
Avigdor Shafferman spends much of his time researching Microbiology, Virology, Virulence, Bacillus anthracis and Immunology.
His Microbiology study combines topics in areas such as Antibody, Yersinia pestis, Immune system and Antigen.
His Virology research includes elements of Genome and Gene.
His Virulence research includes themes of Secretion and Mutant.
The Bacillus anthracis study combines topics in areas such as Toxin, Plasmid and In vivo.
In his study, Intracellular is inextricably linked to Acetylcholinesterase, which falls within the broad field of Molecular biology.
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